Identification
Name:Transcription termination factor Rho
Synonyms:Not Available
Gene Name:rho
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
ATP binding
DNA-templated transcription, termination
helicase activity
identical protein binding
membrane
regulation of transcription, DNA-templated
RNA binding
RNA-dependent ATPase activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1260
atgaatcttaccgaattaaagaatacgccggtttctgagctgatcactctcggcgaaaat
atggggctggaaaacctggctcgtatgcgtaagcaggacattatttttgccatcctgaag
cagcacgcaaagagtggcgaagatatctttggtgatggcgtactggagatattgcaggat
ggatttggtttcctccgttccgcagacagctcctacctcgccggtcctgatgacatctac
gtttcccctagccaaatccgccgtttcaacctccgcactggtgataccatctctggtaag
attcgcccgccgaaagaaggtgaacgctattttgcgctgctgaaagttaacgaagttaac
ttcgacaaacctgaaaacgcccgcaacaaaatcctctttgagaacttaaccccgctgcac
gcaaactctcgtctgcgtatggaacgtggtaacggttctactgaagatttaactgctcgc
gtactggatctggcatcacctatcggtcgtggtcagcgtggtctgattgtggcaccgccg
aaagccggtaaaaccatgctgctgcagaacattgctcagagcattgcttacaaccacccg
gattgtgtgctgatggttctgctgatcgacgaacgtccggaagaagtaaccgagatgcag
cgtctggtaaaaggtgaagttgttgcttctacctttgacgaacccgcatctcgccacgtt
caggttgcggaaatggtgatcgagaaggccaaacgcctggttgagcacaagaaagacgtt
atcattctgctcgactccatcactcgtctggcgcgcgcttacaacaccgttgttccggcg
tcaggtaaagtgttgaccggtggtgtggatgccaacgccctgcatcgtccgaaacgcttc
tttggtgcggcgcgtaacgtggaagagggcggcagcctgaccattatcgcgacggcgctt
atcgataccggttctaaaatggacgaagttatctacgaagagtttaaaggtacaggcaac
atggaactgcacctctctcgtaagatcgctgaaaaacgcgtcttcccggctatcgactac
aaccgttctggtacccgtaaagaagagctgctcacgactcaggaagaactgcagaaaatg
tggatcctgcgcaaaatcattcacccgatgggcgaaatcgatgcaatggaattcctcatt
aataaactggcaatgaccaagaccaatgacgatttcttcgaaatgatgaaacgctcataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:419
Protein Molecular Weight:47003
Protein Theoretical pI:Not Available
PDB File:1A62
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Transcription termination factor Rho
MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQD
GFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVN
FDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPP
KAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV
QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRF
FGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY
NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMMKRS
References
External Links:
ResourceLink
Uniprot ID:P0AG30
Uniprot Name:RHO_ECOLI
PDB ID:1A62
CCDB:RHO_ECOLI
General Reference:Not Available