ECMDB: Putative GTP cyclohydrolase 1 type 2 (P0AFP6)

Identification

Name:

Putative GTP cyclohydrolase 1 type 2

Synonyms:

Not Available

Gene Name:

ybgI

Enzyme Class:

3.5.4.16

Biological Properties

General Function:

7,8-dihydroneopterin 3'-triphosphate biosynthetic process

Specific Function:

Converts GTP to dihydroneopterin triphosphate.

Cellular Location:

Not Available

SMPDB Pathways:

Folate biosynthesis PW000908

KEGG Pathways:

Folate biosynthesis ec00790
Metabolic pathways eco01100

KEGG Reactions:

1.0

↔

1.0

1.0Guanosine triphosphate + 1.0Water ↔ 1.0Formic acid + 1.0Dihydroneopterin triphosphate
ReactionCard

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
7,8-dihydroneopterin 3'-triphosphate biosynthetic process
cytoplasm
GTP binding
GTP cyclohydrolase I activity
metal ion binding

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>744
atgaaaaacaccgaactggaacaactgattaacgaaaaactgaacagcgcggcgattagt
gattacgcgccgaatggtttgcaggtggaaggcaaagagacggtgcaaaaaattgttacc
ggtgtcaccgccagccaggctttgctcgatgaggcagtgcgtctgggcgcggatgcggtc
attgtgcatcatggctacttctggaaaggagagtctccggtcattcgcggaatgaagcgt
aaccgtttaaaaacgttgctggcgaatgatatcaacctgtatggctggcatttgccgctt
gacgcacatcctgagctgggcaataacgcacagctggcggcgttactggggatcacggtc
atgggcgaaattgagccgttggtgccgtggggcgaactgaccatgcctgtgccgggactg
gagctggcttcctggattgaagcgcgtctgggacgtaagccgttatggtgtggcgatacc
ggacctgaggtggtccagcgcgtcgcctggtgcacgggcggcgggcaaagttttatcgat
agcgccgcgcgttttggcgtggatgcttttattactggcgaagtttctgaacagaccatt
cattcagcccgcgagcagggattgcatttttatgctgcaggtcaccatgccactgaacgt
ggtggtattcgcgcattgagcgagtggctgaatgaaaataccgatcttgatgtgaccttt
attgatattcctaatcctgcataa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

247

Protein Molecular Weight:

26892

Protein Theoretical pI:

Not Available

PDB File:

1NMO

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Putative GTP cyclohydrolase 1 type 2
MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAV
IVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITV
MGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGGQSFID
SAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTDLDVTF
IDIPNPA

References

External Links:

Resource	Link
Uniprot ID:	P0AFP6
Uniprot Name:	GTPC1_ECOLI
PDB ID:	1NMO
CCDB:	GTPC1_ECOLI

General Reference:

Not Available