Identification
Name:Low-affinity inorganic phosphate transporter 1
Synonyms:Not Available
Gene Name:pitA
Enzyme Class:Not Available
Biological Properties
General Function:Involved in inorganic phosphate transmembrane transporter activity
Specific Function:Low-affinity inorganic phosphate transport. Can also transport arsenate
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Component
cell part
membrane
Function
anion transmembrane transporter activity
inorganic anion transmembrane transporter activity
inorganic phosphate transmembrane transporter activity
ion transmembrane transporter activity
phosphate transmembrane transporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
anion transport
establishment of localization
inorganic anion transport
ion transport
phosphate transport
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1500 bp
ATGCTACATTTGTTTGCTGGCCTGGATTTGCATACCGGGCTGTTATTATTGCTTGCACTG
GCTTTTGTGCTGTTCTACGAAGCCATCAATGGTTTCCATGACACAGCCAACGCCGTGGCA
ACCGTTATCTATACCCGCGCGATGCGTTCTCAGCTCGCCGTGGTTATGGCAGCGGTGTTC
AACTTTTTGGGTGTTTTGCTGGGTGGTCTGAGTGTTGCCTATGCCATTGTGCATATGCTG
CCGACGGATCTGCTGCTTAATATGGGATCGTCTCATGGCCTTGCCATGGTGTTCTCTATG
TTGCTGGCGGCGATTATCTGGAACCTGGGTACCTGGTACTTTGGTTTGCCTGCATCCAGC
TCTCATACGCTGATTGGCGCGATCATCGGGATTGGTTTAACCAATGCGTTGATGACCGGG
ACGTCAGTGGTGGATGCACTCAATATCCCGAAAGTATTAAGTATTTTCGGTTCTCTGATC
GTTTCCCCTATTGTCGGCCTGGTGTTTGCTGGCGGTCTGATTTTCTTGCTGCGTCGCTAC
TGGAGCGGCACCAAGAAACGCGCCCGTATCCACCTGACCCCAGCGGAGCGTGAAAAGAAA
GACGGCAAGAAAAAGCCGCCGTTCTGGACGCGTATCGCGCTGATCCTTTCCGCTATCGGC
GTGGCGTTTTCGCACGGCGCAAACGATGGTCAGAAAGGCATTGGTCTGGTTATGTTGGTA
TTGATTGGTGTCGCACCAGCAGGCTTCGTGGTGAACATGAATGCCACTGGCTACGAAATC
ACCCGTACCCGTGATGCCATCAACAACGTCGAAGCTTACTTTGAGCAGCATCCTGCGCTG
CTGAAACAAGCTACTGGTGCTGATCAGTTAGTACCGGCTCCGGAAGCTGGCGCAACGCAA
CCTGCGGAGTTCCACTGCCATCCGTCGAATACCATTAACGCGCTCAACCGCCTGAAAGGT
ATGTTGACCACCGATGTGGAAAGCTACGACAAGCTGTCGCTTGATCAACGTAGCCAGATG
CGCCGCATTATGCTGTGCGTTTCTGACACTATCGACAAAGTGGTGAAGATGCCTGGCGTG
AGTGCTGACGATCAGCGCCTGTTGAAGAAACTGAAGTCCGACATGCTTAGCACCATCGAG
TATGCACCGGTGTGGATCATCATGGCGGTCGCGCTGGCGTTAGGTATCGGTACGATGATT
GGCTGGCGTCGTGTGGCAACGACTATCGGTGAGAAAATCGGTAAGAAAGGCATGACCTAC
GCTCAGGGGATGTCTGCCCAGATGACTGCGGCAGTGTCTATCGGCCTGGCGAGTTATACC
GGGATGCCGGTTTCCACTACTCACGTWCTCTCCTCTTCTGTCGCGGGGACGATGGTGGTA
GATGGTGGCGGCTTACAGCGTAAAACCGTGACCAGCATTCTGATGGCCTGGGTGTTTACC
CTTCCGGCTGCGGTACTGCTTTCCGGCGGGCTTTACTGGCTCTCCTTGCAGTTCCTGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:499
Protein Molecular Weight:53389
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • 5-25
  • 52-72
  • 94-114
  • 124-144
  • 155-175
  • 207-227
  • 233-253
  • 382-402
  • 430-450
  • 473-493
Protein Sequence:
>Low-affinity inorganic phosphate transporter 1
MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIYTRAMRSQLAVVMAAVF
NFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLLAAIIWNLGTWYFGLPASS
SHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLIVSPIVGLVFAGGLIFLLRRY
WSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSAIGVAFSHGANDGQKGIGLVMLV
LIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQHPALLKQATGADQLVPAPEAGATQ
PAEFHCHPSNTINALNRLKGMLTTDVESYDKLSLDQRSQMRRIMLCVSDTIDKVVKMPGV
SADDQRLLKKLKSDMLSTIEYAPVWIIMAVALALGIGTMIGWRRVATTIGEKIGKKGMTY
AQGMSAQMTAAVSIGLASYTGMPVSTTHVLSSSVAGTMVVDGGGLQRKTVTSILMAWVFT
LPAAVLLSGGLYWLSLQFL
References
External Links:
ResourceLink
Uniprot ID:P0AFJ9
Uniprot Name:PITA_ECO57
GenBank Gene ID:AE005174
Genebank Protein ID:12518187
EchoBASE ID:EB2142
CCDB:PITA_ECO57
General Reference:
  • Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
  • Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551