Citrate carrier (P0AE75)

Identification
Name:Citrate carrier
Synonyms:
  • Citrate transporter
  • Citrate/succinate antiporter
Gene Name:citT
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transporter activity
Specific Function:Responsible for the uptake of citrate in exchange to the efflux of succinate. Has a relatively broad specificity for C(4)- dicarboxylates and tricarboxylates
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Component
cell part
membrane
Function
transporter activity
Process
cation transport
establishment of localization
ion transport
monovalent inorganic cation transport
sodium ion transport
transmembrane transport
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1463 bp
ATGTCTTTAGCAAAAGATAATATATGGAAACTATTGGCCCCACTGGTGGTGATGGGTGTC
ATGTTTCTTATCCCTGTCCCCGACGGTATGCCGCCGCAGGCATGGCATTACTTCGCTGTG
TTTGTGGCAATGATTGTCGGCATGATCCTCGAGCCAATTCCGGCAACAGCGATCAGTTTT
ATTGCGGTTACTATTTGCGTTATTGGCAGTAATTACCTGCTCTTTGATGCCAAAGAATTA
GCTGACCCAGCGTTTAATGCGCAAAAACAGGCGCTGAAATGGGGCCTGGCTGGTTTTTCC
AGCACTACGGTATGGCTGGTATTTGGCGCATTTATTTTTGCATTAGGGTATGAAGTTTCC
GGGTTAGGTCGTCGCATTGCCCTTTTCCTGGTGAAATTCATGGGCAAACGCACGCTGACG
TTGGGTTATGCGATTGTCATTATCGACATTCTGCTGGCACCGTTTACACCGTCCAACACC
GCGCGTACCGGGGGTACGGTTTTTCCGGTCATTAAAAACCTGCCGCCGTTGTTTAAATCA
TTCCCGAACGATCCGTCCGCGCGTCGTATTGGCGGCTATTTGATGTGGATGATGGTCATT
AGTACCAGTCTGAGTTCGTCCATGTTTGTCACCGGTGCGGCACCAAACGTGCTGGGTCTG
GAGTTCGTCAGCAAAATTGCCGGTATCCAGATTAGCTGGTTGCAGTGGTTCCTCTGCTTC
CTGCCGGTTGGGGTTATCTTGCTTATCATTGCGCCGTGGCTTTCCTACGTGCTGTACAAA
CCGGAAATCACACACAGTGAAGAAGTGGCAACCTGGGCGGGTGATGAACTAAAAACCATG
GGTGCGCTGACACGCAGAGAGTGGACGCTGATTGGCCTTGTATTGCTCAGCTTAGGTTTG
TGGGTATTTGGCAGTGAAGTCATTAATGCTACTGCGGTTGGTCTGCTGGCAGTTTCGCTA
ATGCTGGCTCTGCACGTTGTGCCGTGGAAAGACATTACCCGCTATAACAGCGCATGGAAC
ACGCTGGTCAACCTGGCAACTCTGGTTGTGATGGCTAACGGCCTGACTCGTTCTGGTTTT
ATTGACTGGTTCGCCGGTACCATGAGTACGCACCTGGAAGGATTCTCACCAAACGCAACG
GTGATTGTACTGGTTCTGGTGTTCTACTTTGCACACTACCTGTTTGCCAGCCTGTCTGCG
CACACCGCAACCATGCTGCCGGTTATTCTGGCCGTCGGTAAAGTATTCCGGGCGTACCAA
TGGAACAACTGTGTATCCTGCTGGTGCTGTCTATCGGTATCATGGGCTGTCTGACGCCGT
ATGCAACCGGTCCTGGGGTGATTATTTACGGCTGTGGCTATGTGAAATCAAAAGATTACT
GGCGTCTTGGCGCAATCTTCGGGGTGATTTACATCTCTATGTTGCTGTTGGTTGGCTGGC
CGATTCTCGCCATGTGGAACTAA
Protein Properties
Pfam Domain Function:
Protein Residues:487
Protein Molecular Weight:53092
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • 11-31
  • 60-80
  • 95-115
  • 138-158
  • 190-210
  • 214-234
  • 237-257
  • 288-308
  • 309-329
  • 345-365
  • 379-399
  • 401-421
  • 424-444
  • 463-483
Protein Sequence:
>Citrate carrier
MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAMIVGMILEPIPATAISF
IAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSSTTVWLVFGAFIFALGYEVS
GLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGTVFPVIKNLPPLFKS
FPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVSKIAGIQISWLQWFLCF
LPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDELKTMGALTRREWTLIGLVLLSLGL
WVFGSEVINATAVGLLAVSLMLALHVVPWKDITRYNSAWNTLVNLATLVVMANGLTRSGF
IDWFAGTMSTHLEGFSPNATVIVLVLVFYFAHYLFASLSAHTATMLPVILAVGKGIPGVP
MEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSKDYWRLGAIFGVIYISMLLLVGW
PILAMWN
References
External Links:
ResourceLink
Uniprot ID:P0AE75
Uniprot Name:CITT_ECO57
GenBank Gene ID:AE005174
Genebank Protein ID:12513511
EchoBASE ID:EB3308
CCDB:CITT_ECO57
General Reference:
  • Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
  • Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551