| Identification |
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| Name: | Methionine aminopeptidase |
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| Synonyms: | Not Available |
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| Gene Name: | map |
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| Enzyme Class: | |
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| Biological Properties |
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| General Function: | protein initiator methionine removal |
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| Specific Function: | Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| cytosol | | ferrous iron binding | | metalloaminopeptidase activity | | protein initiator methionine removal |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >795
atggctatctcaatcaagaccccagaagatatcgaaaaaatgcgcgtcgctggccgactg
gctgccgaagtgctggagatgatcgaaccgtatgttaaaccgggcgtcagcaccggcgag
ctggatcgcatctgtaatgattacattgttaatgaacaacacgcggtttctgcctgcctc
ggctatcacggctatccgaaatccgtttgcatctctattaatgaagtggtgtgccacggt
atcccggacgatgctaagctgctgaaagatggcgatatcgttaacattgatgtcaccgta
atcaaagatggtttccacggcgatacctcgaaaatgtttatcgtcggtaagccgaccatc
atgggcgaacgtctgtgccgcatcacgcaagaaagcctgtacctggcgctacgcatggta
aaaccaggcattaatctgcgcgaaatcggtgcggcgattcagaaatttgtcgaagcagaa
ggcttctccgtcgttcgtgaatattgcggacacggtattggtcgcggcttccatgaagaa
ccgcaggtgctgcactatgactcccgtgaaaccaacgtcgtactgaaacctgggatgacg
ttcaccatcgagccaatggtcaacgcgggtaaaaaagagatccgcaccatgaaagatggc
tggacggtaaaaaccaaagatcgcagcttgtctgcacaatatgagcatactattgtggtg
actgataacggctgcgaaattctgacgctacgcaaggatgacaccatcccggcgataatc
tcgcacgacgaataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 264 |
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| Protein Molecular Weight: | 29330 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1C21 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Methionine aminopeptidase
MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACL
GYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTI
MGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEE
PQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVV
TDNGCEILTLRKDDTIPAIISHDE |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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