ECMDB

Identification

Name:

Transcriptional regulatory protein CusR

Synonyms:

Not Available

Gene Name:

cusR

Enzyme Class:

Not Available

Biological Properties

General Function:

transcription, DNA-templated

Specific Function:

Member of the two-component regulatory system CusS/CusR. Activates the expression of cusCFBA and plasmid pRJ1004 gene pcoE in response to increasing levels of copper ions, and probably silver ions. Can also increase the basal-level expression of copper resistance gene operon pcoABCD.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Two-component system ec02020

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
core promoter sequence-specific DNA binding
cytoplasm
DNA binding
identical protein binding
phosphorelay signal transduction system
positive regulation of gene expression
protein-DNA complex
regulation of transcription, DNA-templated
response to copper ion
transcription, DNA-templated

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>684
atgaaactgttgattgtcgaagatgaaaagaaaaccggagaatacttgaccaaagggtta
accgaagccggttttgtggtcgatttggccgacaacgggctgaatggctaccatctggcg
atgaccggtgattatgatctgataatcctcgatattatgctgccggacgtgaacggctgg
gatatcgtgcgcatgttacgctccgccaataaagggatgccgattctgttgcttaccgcg
cttggcaccattgaacatcgcgtcaaggggctggagttgggggcagatgactacctggtg
aagccattcgcttttgctgaactgctggcgcgggtgcgcacattactgcggcgcggggcg
gcggtgattatcgaaagtcagtttcaggttgccgatttgatggtcgatctcgtcagccgc
aaagtcacccgcagcggcacgcgcatcactttgaccagtaaagagtttactctgctggag
ttcttccttcgccatcagggcgaagtgctgccccgctcgcttatcgcctcgcaggtatgg
gacatgaattttgacagcgataccaatgctattgatgtggcggtgaagcggctgcgcggc
aaaatcgacaacgactttgagccgaagctaattcagaccgtgcgcggcgtgggttacatg
cttgaggtgccggatggtcagtaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

227

Protein Molecular Weight:

25394

Protein Theoretical pI:

Not Available

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Transcriptional regulatory protein CusR
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGW
DIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGA
AVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLEFFLRHQGEVLPRSLIASQVW
DMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ

References

External Links:

Resource	Link
Uniprot ID:	P0ACZ8
Uniprot Name:	CUSR_ECOLI
CCDB:	CUSR_ECOLI

General Reference:

Not Available

Transcriptional regulatory protein CusR (P0ACZ8)