ECMDB: Protein mpaA (P0ACV6)

Identification

Name:

Protein mpaA

Synonyms:

Not Available

Gene Name:

mpaA

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in metallocarboxypeptidase activity

Specific Function:

Specific function unknown

Cellular Location:

Cytoplasmic

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

EcoCyc Reactions:

1.0

→

1.0

1.0meso-diaminopimelate

1.0L-Ala-gamma-D-Glu-Dap + 1.0Water → 1.0L-Ala-gamma-D-Glu + 1.0meso-diaminopimelate
ReactionCard

Complex Reactions:

1.0

→

1.0

1.0L-alanine-D-glutamate-meso-2,6-diaminoheptanedioate + 1.0Water → 1.0Diaminopimelic acid + 1.0L-Alanyl-D-glutamate
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB01370	Diaminopimelic acid	MetaboCard
ECMDB20574	L-Ala-gamma-D-Glu	MetaboCard
ECMDB20575	L-Ala-gamma-D-Glu-Dap	MetaboCard
ECMDB21240	L-alanine-D-glutamate-meso-2,6-diaminoheptanedioate	MetaboCard
ECMDB21241	L-Alanyl-D-glutamate	MetaboCard
ECMDB00494	Water	MetaboCard

GO Classification:

Function
binding
carboxypeptidase activity
catalytic activity
cation binding
exopeptidase activity
hydrolase activity
ion binding
metal ion binding
metallocarboxypeptidase activity
peptidase activity
peptidase activity, acting on L-amino acid peptides
transition metal ion binding
zinc ion binding
Process
macromolecule metabolic process
metabolic process
protein metabolic process
proteolysis

Gene Properties

Blattner:

b1326

Gene Orientation

Counterclockwise

Centisome Percentage:

29.91

Left Sequence End

1387894

Right Sequence End

1388622

Gene Sequence:

>729 bp
GTGAATGTTATGAACACTATCGTATTTGTGGAAGATGATGCGGAAGTCGGTTCACTGATT
GCCGCGTACCTGGCAAAACATGATATGCAGGTTACCGTAGAGCCGCGCGGCGACCAGGCC
GAAGAAACCATTTTGCGAGAAAATCCGGATTTGGTGTTACTCGACATCATGCTACCAGGC
AAGGACGGCATGACCATTTGTCGTGATTTACGCGCAAAGTGGTCTGGACCGATTGTTCTT
CTAACCTCTCTCGATAGCGATATGAACCACATCCTGGCACTGGAAATGGGTGCCTGCGAC
TATATTCTCAAAACGACGCCCCCTGCTGTTTTGCTAGCGCGTTTACGTTTGCATTTGCGT
CAGAATGAGCAAGCCACACTGACCAAAGGTCTTCAGGAAACGTCTCTGACTCCCTACAAA
GCCCTGCATTTCGGCACGTTGACCATCGATCCCATCAACCGCGTAGTCACCCTGGCTAAC
ACTGAAATCTCGCTCTCGACAGCTGATTTCGAATTATTGTGGGAATTAGCTACCCATGCC
GGGCAAATCATGGACCGCGATGCATTGCTGAAAAATTTACGCGGCGTCAGTTATGACGGA
CTGGATCGTAGCGTGGACGTGGCTATTTCGCGGTTAAGAAAAAAACTGCTCGATAACGCC
GCAGAACCTTATCGCATTAAAACTGTGCGTAACAAAGGCTATCTTTTTGCGCCTCATGCA
TGGGAATAA

Protein Properties

Pfam Domain Function:

Peptidase_M14 (PF00246 )

Protein Residues:

242

Protein Molecular Weight:

26558

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

None

Protein Sequence:

>Protein mpaA
MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLS
CALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAE
ERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPLACIEDPRHSELGEWLAQAFE
LPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
PS

References

External Links:

Resource	Link
Uniprot ID:	P0ACV6
Uniprot Name:	MPAA_ECOLI
GenBank Gene ID:	AP009048
Genebank Protein ID:	1742647
Ecogene ID:	EG13906
Ecocyc:	EG13906
ColiBase:	b1326
Kegg Gene:	b1326
EchoBASE ID:	EB3665
CCDB:	MPAA_ECOLI
BacMap:	226524711

General Reference:

Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kasai, H., Kashimoto, K., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Horiuchi, T., et, a. l. .. (1996). "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." DNA Res 3:363-377. Pubmed: 9097039
Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
Cha, M. K., Kim, H. K., Kim, I. H. (1995). "Thioredoxin-linked "thiol peroxidase" from periplasmic space of Escherichia coli." J Biol Chem 270:28635-28641. Pubmed: 7499381
Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553