| Identification |
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| Name: | Leucine-responsive regulatory protein |
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| Synonyms: | Not Available |
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| Gene Name: | lrp |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | transcription, DNA-templated |
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| Specific Function: | Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | - Operon: acetolactate synthase III activation PW001881
- Operon: acetolactate synthase III inactivation PW001882
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| identical protein binding | | intracellular | | leucine biosynthetic process | | regulation of transcription, DNA-templated | | response to leucine | | sequence-specific DNA binding | | sequence-specific DNA binding transcription factor activity | | transcription, DNA-templated |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >495
atggtagatagcaagaagcgccctggcaaagatctcgaccgtatcgatcgtaacattctt
aatgagttgcaaaaggatgggcgtatttctaacgtcgagctttctaaacgtgtgggactt
tccccaacgccgtgccttgagcgtgtgcgtcggctggaaagacaagggtttattcagggc
tatacggcgctgcttaacccccattatctggatgcatcacttctggtattcgttgagatt
actctgaatcgtggcgcaccggatgtgtttgaacaattcaataccgctgtacaaaaactt
gaagaaattcaggagtgtcatttagtatccggtgatttcgactacctgttgaaaacacgc
gtgccggatatgtcagcctaccgtaagttgctgggggaaaccctgctgcgtctgcctggc
gtcaatgacacacggacatacgttgttatggaagaagtcaagcagagtaatcgtctggtt
attaagacgcgctaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 164 |
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| Protein Molecular Weight: | 18886 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 2GQQ |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Leucine-responsive regulatory protein
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQG
YTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTR
VPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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