Identification
Name:Flagellar protein FliT
Synonyms:Not Available
Gene Name:fliT
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
bacterial-type flagellum organization
cytosol
negative regulation of bacterial-type flagellum assembly
protein folding
regulation of transcription, DNA-templated
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>366
atgaaccatgcaccgcatttatatttcgcctggcaacaactcgtcgaaaaaagccagctc
atgttacgcctggcaacggaagaacaatgggacgaactcatcgccagcgaaatggcgtat
gtgaatgcggtgcaggagattgcacatttgactgaagaggttgacccgtccaccacgatg
caggagcagctccgcccgatgctgcgcctgattctcgacaacgaaagcaaggtaaagcag
ttattacagattcggatggatgaactggcgaaactggtcggtcagtcatcggtgcaaaaa
tcggtgttaagtgcctatggcgatcagggcggctttgtgctggctccgcaggataacctc
ttttga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:121
Protein Molecular Weight:13828
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Flagellar protein FliT
MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTM
QEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNL
F
References
External Links:
ResourceLink
Uniprot ID:P0ABY2
Uniprot Name:FLIT_ECOLI
CCDB:FLIT_ECOLI
General Reference:Not Available