ECMDB: Anaerobic C4-dicarboxylate transporter dcuA (P0ABN7)

Identification

Name:

Anaerobic C4-dicarboxylate transporter dcuA

Synonyms:

Not Available

Gene Name:

dcuA

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in C4-dicarboxylate transmembrane transporter activity

Specific Function:

Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane

Cellular Location:

Cell inner membrane; Multi-pass membrane protein

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Function
C4-dicarboxylate transmembrane transporter activity
carboxylic acid transmembrane transporter activity
dicarboxylic acid transmembrane transporter activity
organic acid transmembrane transporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
C4-dicarboxylate transport
carboxylic acid transport
dicarboxylic acid transport
establishment of localization
organic acid transport
transport

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>1302 bp
ATGAAAAAACTGTTTATCCAGTTTTACCTGTTATTGTTTGTCTGCTTCCTTGTGATGTCT
CTGCTGGTTGGGTTGGTGTACAAATTTACCGCCGAACGCGCGGGCAAACAGTCGCTGGAT
GATTTGATGAACAGTTCGCTGTATCTGATGCGCAGCGAATTGCGTGAGATCCCCCCACAT
GACTGGGGTAAGACGCTGAAAGAGATGGATTTAAATCTCTCTTTCGATCTGCGAGTCGAG
CCACTGAGTAAATACCATCTTGATGATATTTCCATGCACCGGCTGCGTGGCGGCGAAATT
GTCGCCCTGGACGATCAGTACACTTTTTTGCAGCGTATCCCGCGCAGCCACTACGTGCTG
GCAGTTGGTCCTGTTCCTTATCTTTATTATCTCCATCAGATGCGATTGCTGGATATCGCC
CTGATCGCTTTTATTGCTATTTCCCTCGCCTTTCCGGTGTTTATCTGGATGCGTCCGCAC
TGGCAGGATATGTTAAAACTGGAAGCAGCGGCGCAACGATTTGGCGATGGGCATCTCAAT
GAACGTATCCACTTTGATGAGGGTTCGAGCTTTGAACGACTTGGTATCGCATTTAACCAG
ATGGCGGACAATATCAACGCCTTGATTGCCAGCAAAAAACAGCTTATTGACGGTATCGCT
CACGAACTGCGAACACCGTTAGTGCGCCTGCGTTATCGACTGGAGATGAGCGATAACCTG
AGCGCCGCCGAATCCCAGGCGTTGAATCGTGATATCAGTCAACTTGAAGCTTTAATTGAA
GAGCTGCTGACTTATGCCCGACTCGATCGCCCACAAAACGAGCTTCATCTTAGCGAACCA
GACCTGCCGTTGTGGCTGTCAACGCATCTGGCAGATATTCAGGCAGTAACGCCCGATAAA
ACGGTACGGATAAAAACGCTCATGCAAGGCCATTATGCGGCGTTGGATATGCGCTTAATG
GAGCGCGTGCTGGATAATTTGCTCAATAATGCCCTGCGCTACTGCCATTCAACGGTTGAA
ACCAGCCTGCTACTGTCGGGGAATAGAGCGACATTAATTGTTGAGGATGATGGCCCAGGG
ATTGCCCCAGAAAACCGCGAACATATCTTTGAACCTTTTGTTCGCCTCGATCCCAGCCGG
GATCGCTCAACCGGCGGCTGCGGGCTGGGGCTGGCAATTGTCCACTCTATAGCACTGGCA
ATGGGCGGTACGGTTAATTGTGACACCAGCGAACTGGGTGGTGCCCGCTTCTCGTTTAGC
TGGCCGTTATGGCATAACATCCCGCAATTTACCTCTGCTTGA

Protein Properties

Pfam Domain Function:

DcuA_DcuB (PF03605 )

Protein Residues:

433

Protein Molecular Weight:

45750

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

1-18
20-37
54-71
86-103
133-147
229-246
265-282
293-310
333-350
356-373

Protein Sequence:

>Anaerobic C4-dicarboxylate transporter dcuA
MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI
SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK
EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL
VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY
AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI
LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA
LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL
AVCFGFVLGSFML

References

External Links:

Resource	Link
Uniprot ID:	P0ABN7
Uniprot Name:	DCUA_ECO57
GenBank Gene ID:	AE005174
Genebank Protein ID:	12515590
EchoBASE ID:	EB1207
CCDB:	DCUA_ECO57

General Reference:

Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551