Identification
Name:Probable galactarate transporter
Synonyms:
  • D-galactarate permease
Gene Name:garP
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transporter activity
Specific Function:Uptake of D-galactarate
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:
  • superpathway of D-glucarate and D-galactarate degradation PW000795
KEGG Pathways:Not Available
Transports:
Transport References:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Function
transporter activity
Process
establishment of localization
transmembrane transport
transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1335 bp
ATGTCGGATATGAAAAGCGGAAACATATCGATGAAAGCGATCTTGATCCCATTTTTATCT
CTTCTGATTCCGTTAACCCCGCAATCTGCATTCGCTCAGAGTGAGCCGGAGCCGGAGCTG
AAGCTGGAAAGTGTGGTGATTGTCAGTCGTCATGGTGTGCGTGCCCCAACCAAGGCCACG
CAACTGATGCAGGATGTCACCCCAGACGCATGGCCAAACTGGCCGGTAAAACTGGGTTGG
CTGACACCGCGCGGTGGTGAGCTAATCGCTTATCTCGGACATTACCAACGCCAGCGTCTG
GTAGCCGACGGATTGCTGACGAAAAAGGGCTGCCCGCAGCCTGGTCAGGTCGCGATTATT
GCTGATGTCGACGAGCGTACCCGTAAAACAGGCGAAGCCTTCGCCGCCGGGCTGGCACCT
GACTGTGCAATAACCGTACATACCCAGGCAGATACGTCCAGTCCCGATCCGTTATTTAAT
CCTCTAAAAACTGGCGTTTGCCAACTGGATAACGCGAACGTGACTGACGCGATCCTCAGC
AGGGCAGGAGGGTCAATTGCTGACTTTACCGGGCATCGGCAAACGGCGTTTCGCGAACTG
GAACGGGTGCTTAATTTTCCGCAATCAAACTTGTGCCTTAACCGTGAGAAACAGGACGAA
AGCTGTTCATTAACGCAGGCATTACCATCGGAACTCAAGGTGAGCGCCGACAATGTCTCA
TTAACCGGTGCGGTAAGCCTCGCATCAATGCTGACGGAAATATTTCTCCTGCAACAGGCA
CAGGGAATGCCGGAGCCGGGGTGGGGAAGGATCACTGATTCACACCAGTGGAACACGTTG
CTAAGTTTGCATAACGCGCAATTTTATTTACTACAACGCACGCCAGAGGTTGCCCGCAGC
CGCGCCACCCCGTTGTTGGATTTGATCATGATAGCGTTGACTCCCCATCCACCGCAAAAA
CAGGCGTATGGTGTGACATTACCCACTTCAGTGCTGTTTATCGCCGGACACGATACTAAT
CTGGCAAATCTCGGCGGCGCACTGGAGCTCAACTGGACGCTTCCAGGTCAGCCGGATAAC
ACGCCGCCAGGTGGTGAACTGGTGTTTGAACGCTGGCGTCGGCTAAGCGATAACAGCCAG
TGGATTCAGGTTTCGCTGGTCTTCCAGACTTTACAGCAGATGCGTGATAAAACTCCGCTG
TCATTAAATACGCCGCCCGGAGAGGTGAAACTGACCCTGGCAGGATGTGAAGAGCGAAAT
GCGCAGGGCATGTGTTCGTTGGCCGGTTTTACGCAAATCGTGAATGAAGCACGCATACCG
GCGTGCAGTTTGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:444
Protein Molecular Weight:49009
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • 12-32
  • 57-77
  • 90-110
  • 111-131
  • 158-178
  • 179-199
  • 253-273
  • 289-309
  • 320-340
  • 351-371
  • 386-406
  • 414-434
Protein Sequence:
>Probable galactarate transporter
MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFS
AFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRF
MLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHV
FTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKL
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF
AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFG
KGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVG
CSALMAMVCYLFVVGDIKRMELQK
References
External Links:
ResourceLink
Uniprot ID:P0AA81
Uniprot Name:GARP_ECO57
GenBank Gene ID:AE005174
Genebank Protein ID:12514245
EchoBASE ID:EB2613
CCDB:GARP_ECO57
General Reference:
  • Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
  • Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551