Identification
Name:Aerobic respiration control protein ArcA
Synonyms:Not Available
Gene Name:arcA
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. Controls the resistance of E.coli to dyes; required for expression of the alkaline phosphatase and sex factor F genes; It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA binding
identical protein binding
negative regulation of transcription, DNA-templated
phosphorelay response regulator activity
phosphorelay signal transduction system
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>717
atgcagaccccgcacattcttatcgttgaagacgagttggtaacacgcaacacgttgaaa
agtattttcgaagcggaaggctatgatgttttcgaagcgacagatggcgcggaaatgcat
cagatcctctctgaatatgacatcaacctggtgatcatggatatcaatctgccgggtaag
aacggtcttctgttagcgcgtgaactgcgcgagcaggcgaatgttgcgttgatgttcctg
actggccgtgacaacgaagtcgataaaattctcggcctcgaaatcggtgcagatgactac
atcaccaaaccgttcaacccgcgtgaactgacgattcgtgcacgcaacctactgtcccgt
accatgaatctgggtactgtcagcgaagaacgtcgtagcgttgaaagctacaagttcaat
ggttgggaactggacatcaacagccgttcgttgatcggccctgatggcgagcagtacaag
ctgccgcgcagcgagttccgcgccatgcttcacttctgtgaaaacccaggcaaaattcag
tcccgtgctgaactgctgaagaaaatgaccggccgtgagctgaaaccgcacgaccgtact
gtagacgtgacgatccgccgtattcgtaaacatttcgaatctacgccggatacgccggaa
atcatcgccaccattcacggtgaaggttatcgcttctgcggtgatctggaagattaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:238
Protein Molecular Weight:27291
Protein Theoretical pI:Not Available
PDB File:1XHE
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Aerobic respiration control protein ArcA
MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK
NGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLSR
TMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYKLPRSEFRAMLHFCENPGKIQ
SRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDTPEIIATIHGEGYRFCGDLED
References
External Links:
ResourceLink
Uniprot ID:P0A9Q1
Uniprot Name:ARCA_ECOLI
PDB ID:1XHE
CCDB:ARCA_ECOLI
General Reference:Not Available