Identification
Name:Ferric uptake regulation protein
Synonyms:Not Available
Gene Name:fur
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA binding
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
zinc ion binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>447
atgactgataacaataccgccctaaagaaagctggcctgaaagtaacgcttcctcgttta
aaaatcctggaagttcttcaggagccggacaaccatcacgtcagtgcggaagatttatac
aaacgtctgatcgatatgggtgaagaaattggtctggctacggtatatcgcgtactgaac
cagtttgacgacgctggtatcgtcacccgccacaattttgaaggcggtaaatccgtattt
gaactgacacagcaacatcaccacgatcacctgatctgcctcgactgcggcaaggttatc
gaatttagtgatgattccatcgaagcgcgtcagcgtgaaattgccgcaaaacatggcatt
cgcctgactaaccacagtctctatctttacggtcactgtgccgaaggcgattgccgcgaa
gatgaacatgcgcacgaaggcaaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:148
Protein Molecular Weight:16794
Protein Theoretical pI:Not Available
PDB File:2FU4
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Ferric uptake regulation protein
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLN
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGI
RLTNHSLYLYGHCAEGDCREDEHAHEGK
References
External Links:
ResourceLink
Uniprot ID:P0A9A9
Uniprot Name:FUR_ECOLI
PDB ID:2FU4
CCDB:FUR_ECOLI
General Reference:Not Available