ECMDB

Identification

Name:

Ferric uptake regulation protein

Synonyms:

Not Available

Gene Name:

fur

Enzyme Class:

Not Available

Biological Properties

General Function:

transcription, DNA-templated

Specific Function:

Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cytoplasm
DNA binding
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
zinc ion binding

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>447
atgactgataacaataccgccctaaagaaagctggcctgaaagtaacgcttcctcgttta
aaaatcctggaagttcttcaggagccggacaaccatcacgtcagtgcggaagatttatac
aaacgtctgatcgatatgggtgaagaaattggtctggctacggtatatcgcgtactgaac
cagtttgacgacgctggtatcgtcacccgccacaattttgaaggcggtaaatccgtattt
gaactgacacagcaacatcaccacgatcacctgatctgcctcgactgcggcaaggttatc
gaatttagtgatgattccatcgaagcgcgtcagcgtgaaattgccgcaaaacatggcatt
cgcctgactaaccacagtctctatctttacggtcactgtgccgaaggcgattgccgcgaa
gatgaacatgcgcacgaaggcaaataa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

148

Protein Molecular Weight:

16794

Protein Theoretical pI:

Not Available

PDB File:

2FU4

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Ferric uptake regulation protein
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLN
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGI
RLTNHSLYLYGHCAEGDCREDEHAHEGK

References

External Links:

Resource	Link
Uniprot ID:	P0A9A9
Uniprot Name:	FUR_ECOLI
PDB ID:	2FU4
CCDB:	FUR_ECOLI

General Reference:

Not Available

Ferric uptake regulation protein (P0A9A9)