Identification
Name:30S ribosomal protein S19
Synonyms:Not Available
Gene Name:rpsS
Enzyme Class:Not Available
Biological Properties
General Function:translation
Specific Function:In the E.coli 70S ribosome in the initiation state (PubMed:12809609) it has been modeled to contact the 23S rRNA of the 50S subunit forming part of bridge B1a; this bridge is broken in the model with bound EF-G. The 23S rRNA contact site in bridge B1a is modeled to differ in different ribosomal states (PubMed:12859903), contacting alternately S13 or S19. In the 3.5 angstroms resolved ribosome structures (PubMed:16272117) the contacts between L5, S13 and S19 bridge B1b are different, confirming the dynamic nature of this interaction. Bridge B1a is not visible in the crystallized ribosomes due to 23S rRNA disorder.Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. Contacts the A site tRNA.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytosolic small ribosomal subunit
poly(A) RNA binding
ribosomal small subunit assembly
rRNA binding
structural constituent of ribosome
translation
tRNA binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>279
atgccacgttctctcaagaaaggtccttttattgacctgcacttgctgaagaaggtagag
aaagcggtggaaagcggagacaagaagcccctgcgcacttggtcccgtcgttcaacgatc
tttcctaacatgatcggtttgaccatcgctgtccataatggtcgtcagcacgttccggta
tttgtaaccgacgaaatggttggtcacaaactgggtgaattcgcaccgactcgtacttat
cgcggccacgctgctgataaaaaagcgaagaagaaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:92
Protein Molecular Weight:10430
Protein Theoretical pI:Not Available
PDB File:1M5G
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>30S ribosomal protein S19
MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPV
FVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
References
External Links:
ResourceLink
Uniprot ID:P0A7U3
Uniprot Name:RS19_ECOLI
PDB ID:1M5G
CCDB:RS19_ECOLI
General Reference:Not Available