| Identification |
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| Name: | Chaperone protein DnaK |
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| Synonyms: | Not Available |
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| Gene Name: | dnaK |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | response to heat |
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| Specific Function: | Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ADP binding | | ATP binding | | cellular response to unfolded protein | | chaperone cofactor-dependent protein refolding | | chaperone mediated protein folding requiring cofactor | | cytoplasm | | DNA replication | | membrane | | plasma membrane | | protein binding involved in protein folding | | protein complex assembly | | protein complex disassembly | | protein unfolding | | response to heat | | unfolded protein binding | | zinc ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1917
atgggtaaaataattggtatcgacctgggtactaccaactcttgtgtagcgattatggat
ggcaccactcctcgcgtgctggagaacgccgaaggcgatcgcaccacgccttctatcatt
gcctatacccaggatggtgaaactctagttggtcagccggctaaacgtcaggcagtgacg
aacccgcaaaacactctgtttgcgattaaacgcctgattggtcgccgcttccaggacgaa
gaagtacagcgtgatgtttccatcatgccgttcaaaattattgctgctgataacggcgac
gcatgggtcgaagttaaaggccagaaaatggcaccgccgcagatttctgctgaagtgctg
aaaaaaatgaagaaaaccgctgaagattacctgggtgaaccggtaactgaagctgttatc
accgtaccggcatactttaacgatgctcagcgtcaggcaaccaaagacgcaggccgtatc
gctggtctggaagtaaaacgtatcatcaacgaaccgaccgcagctgcgctggcttacggt
ctggacaaaggcactggcaaccgtactatcgcggtttatgacctgggtggtggtactttc
gatatttctattatcgaaatcgacgaagttgacggcgaaaaaaccttcgaagttctggca
accaacggtgatacccacctggggggtgaagacttcgacagccgtctgatcaactatctg
gttgaagaattcaagaaagatcagggcattgacctgcgcaacgatccgctggcaatgcag
cgcctgaaagaagcggcagaaaaagcgaaaatcgaactgtcttccgctcagcagaccgac
gttaacctgccatacatcactgcagacgcgaccggtccgaaacacatgaacatcaaagtg
actcgtgcgaaactggaaagcctggttgaagatctggtaaaccgttccattgagccgctg
aaagttgcactgcaggacgctggcctgtccgtatctgatatcgacgacgttatcctcgtt
ggtggtcagactcgtatgccaatggttcagaagaaagttgctgagttctttggtaaagag
ccgcgtaaagacgttaacccggacgaagctgtagcaatcggtgctgctgttcagggtggt
gttctgactggtgacgtaaaagacgtactgctgctggacgttaccccgctgtctctgggt
atcgaaaccatgggcggtgtgatgacgacgctgatcgcgaaaaacaccactatcccgacc
aagcacagccaggtgttctctaccgctgaagacaaccagtctgcggtaaccatccatgtg
ctgcagggtgaacgtaaacgtgcggctgataacaaatctctgggtcagttcaacctagat
ggtatcaacccggcaccgcgcggcatgccgcagatcgaagttaccttcgatatcgatgct
gacggtatcctgcacgtttccgcgaaagataaaaacagcggtaaagagcagaagatcacc
atcaaggcttcttctggtctgaacgaagatgaaatccagaaaatggtacgcgacgcagaa
gctaacgccgaagctgaccgtaagtttgaagagctggtacagactcgcaaccagggcgac
catctgctgcacagcacccgtaagcaggttgaagaagcaggcgacaaactgccggctgac
gacaaaactgctatcgagtctgcgctgactgcactggaaactgctctgaaaggtgaagac
aaagccgctatcgaagcgaaaatgcaggaactggcacaggtttcccagaaactgatggaa
atcgcccagcagcaacatgcccagcagcagactgccggtgctgatgcttctgcaaacaac
gcgaaagatgacgatgttgtcgacgctgaatttgaagaagtcaaagacaaaaaataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 638 |
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| Protein Molecular Weight: | 69114 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1BPR |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Chaperone protein DnaK
MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVT
NPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVL
KKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYG
LDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYL
VEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKV
TRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKE
PRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPT
KHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDA
DGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGD
HLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLME
IAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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