| Identification |
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| Name: | UvrABC system protein A |
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| Synonyms: | Not Available |
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| Gene Name: | uvrA |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | SOS response |
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| Specific Function: | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP binding | | ATPase activity | | cytoplasm | | DNA binding | | DNA repair | | excinuclease ABC activity | | excinuclease repair complex | | nucleotide-excision repair | | SOS response | | zinc ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >2823
atggataagatcgaagttcggggcgcccgcacccataatctcaaaaacatcaacctcgtt
atcccccgcgacaagctcattgtcgtgaccgggctttcgggttctggcaaatcctcgctc
gctttcgacaccttatatgccgaagggcagcgccgttacgttgaatccctttccgcctac
gcgcggcagtttctgtcactgatggaaaagccggacgtcgatcatattgaggggctttct
cctgccatctcaattgagcagaaatcgacgtctcataacccgcgttctacggtggggaca
atcaccgaaatccacgactatttgcgtttgttattcgcccgcgttggcgagccgcgctgt
ccggaccacgacgtcccgctggcggcgcaaaccgtcagccagatggtggataacgtgctg
tcgcagccggaaggcaagcgtctgatgctactcgcgccaatcattaaagagcgcaaaggc
gaacacaccaaaacgctggagaacctggcaagccagggctacatccgtgctcgtattgat
ggcgaagtctgcgatctttccgatccgccaaaactggaactgcaaaagaaacataccatt
gaagtggtggttgatcgcttcaaggtgcgtgacgatcttacccaacgtcttgccgagtca
tttgaaaccgcgctggagctttccggtggtaccgcggtagtggcggatatggacgacccg
aaagcggaagagctgctgttctccgccaacttcgcctgcccaatttgcggctacagtatg
cgtgaactggagccgcgactgttttcgtttaacaacccggcgggggcctgcccgacctgc
gacggccttggcgtacagcaatatttcgatcctgatcgagtgatccagaatccggaactg
tcgctggctggtggtgcgatccgtggctgggatcgccgcaacttctattatttccagatg
ctgaaatcgctggcagatcactataagttcgacgtcgaagcgccgtggggcagcctgagc
gcgaacgtgcataaagtggtgttgtacggttctggcaaagaaaacattgaattcaaatac
atgaacgatcgtggcgatacctccattcgtcgtcatccgttcgaaggcgtgctgcataat
atggagcgccgctataaagagacggaatccagcgcggtacgcgaagaattagccaagttt
atcagtaatcgtccgtgcgccagctgcgaagggacgcgtctgcgtcgggaagcgcgccac
gtgtatgtcgagaatacgccgctgcctgctatctccgacatgagcattggtcatgcgatg
gaattcttcaacaatctcaaactcgcaggtcagcgggcgaagattgcagaaaaaatcctt
aaagagatcggcgatcgtctgaaattcctcgttaacgtcggcctgaattacctgacgctt
tcccgctcggcagaaacgctttctggcggtgaagcacagcgtatccgtctggcgagccag
attggtgcgggcctggttggcgttatgtacgtgctggacgagccgtctatcggcctgcac
cagcgtgataacgagcgcctgttgggtacgcttatccatctgcgcgatctcggtaatacc
gtgattgtggtggagcacgacgaagacgcaattcgcgccgctgaccatgtgatcgacatt
ggcccgggcgcaggtgttcacggcggtgaagtggtcgcagaaggtccgctggaagcgatt
atggcggtgccggagtcgttgaccgggcagtacatgagcggcaaacgcaagattgaagtg
ccgaagaaacgcgttccggcgaatccggaaaaagtgctgaagctgacaggcgcacgcggc
aacaacctgaaggacgtgacgctgacgctgccggtgggtctgtttacctgcatcaccggg
gtttcaggttccggtaaatcgacgctgattaacgacacactgttcccgattgcccaacgc
cagttgaatggggcgaccatcgccgaaccagcaccgtatcgcgatattcaggggctggag
catttcgataaagtgatcgatatcgaccaaagcccaattggtcgtactccacgttctaac
ccggcgacctataccggcgtgtttacgcctgtgcgcgaactgtttgcgggcgtaccggaa
tcccgtgcgcgcggctatacgccgggacgtttcagctttaacgttcgtggcggacgctgc
gaggcctgtcagggcgatggcgtgatcaaagtggagatgcacttcctgccggatatctac
gtgccgtgcgaccagtgcaaaggtaaacgctataaccgtgaaacgctggagattaagtac
aaaggcaaaaccatccacgaagtgctggatatgaccatcgaagaggcgcgtgagttcttt
gatgccgtacctgcactggcgcgtaagctgcaaacgttgatggacgttggcctgacgtac
attcgactggggcagtccgcaaccaccctttcaggcggtgaagcccagcgcgtgaagctg
gcgcgtgaactgtcaaaacgcggcaccgggcagacgctgtatattctcgacgagccgacc
accggtctgcacttcgccgatattcagcaactgctcgacgtactgcataaactgcgcgat
cagggcaacaccattgtggtgattgagcacaatctcgacgtgatcaaaaccgctgactgg
attgtcgacctgggaccagaaggcggcagtggtggcggcgagatcctcgtctccggtacg
ccagaaaccgtcgcggagtgcgaagcatcacacacggcacgcttccttaagccgatgctg
taa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 940 |
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| Protein Molecular Weight: | 103866 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 4DFC |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >UvrABC system protein A
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAY
ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRC
PDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARID
GEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPEL
SLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKY
MNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLRREARH
VYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNT
VIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEV
PKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQR
QLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKY
KGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKL
ARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADW
IVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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