ECMDB

Identification

Name:

DNA mismatch repair protein MutH

Synonyms:

Not Available

Gene Name:

mutH

Enzyme Class:

Not Available

Biological Properties

General Function:

regulation of DNA recombination

Specific Function:

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Mismatch repair eco03430

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
cytoplasm
DNA binding
DNA modification
endonuclease activity
mismatch repair
mismatch repair complex
nucleic acid phosphodiester bond hydrolysis
regulation of DNA recombination
T/G mismatch-specific endonuclease activity

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>690
atgtcccaacctcgcccactgctctctcctcccgaaactgaagaacagttgttagcgcaa
gcacagcaactttctggttatacattgggagaactggcggcacttgtcgggctggttacg
ccagagaatttaaaacgcgataaaggctggattggcgtgttactggagatctggctaggt
gccagcgcagggagtaaacctgagcaagattttgctgctctgggcgtggaacttaaaact
atccctgtggatagtcttggtcgtccgctggaaacaacattcgtttgtgttgccccgtta
acgggcaatagcggggtgacctgggaaaccagccacgtgcgccacaaactcaaacgcgta
ctgtggataccggttgaaggcgagcgcagcatcccgctggcgcagcgtcgcgttggatca
ccgttgctgtggagcccgaatgaagaggaagaccggcagctacgcgaagactgggaagaa
ttaatggatatgattgttctcggtcaggttgagcggattaccgctcgtcacggggagtat
ttacagatacgaccgaaagcagcgaatgcgaaagcgcttaccgaagccattggtgcccgg
ggcgaacggattctgacgctgccacgcggcttttatttgaagaagaatttcaccagtgca
ctactggcccgtcattttctgatccagtag

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

229

Protein Molecular Weight:

25527

Protein Theoretical pI:

Not Available

PDB File:

1AZO

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>DNA mismatch repair protein MutH
MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALVGLVTPENLKRDKGWIGVLLEIWLG
ASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRV
LWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQVERITARHGEY
LQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ

References

External Links:

Resource	Link
Uniprot ID:	P06722
Uniprot Name:	MUTH_ECOLI
PDB ID:	1AZO
CCDB:	MUTH_ECOLI

General Reference:

Not Available

DNA mismatch repair protein MutH (P06722)