Identification
Name:HTH-type transcriptional regulator AppY
Synonyms:Not Available
Gene Name:appY
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cellular response to phosphate starvation
positive regulation of transcription, DNA-templated
sequence-specific DNA binding
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>750
atggattatgtttgctccgtagttttcatctgtcaatcatttgatttaattataaacagg
agagttatctcgttcaaaaaaaattcattgtttattgtaagcgacaaaattagaagggag
ttaccagtatgcccctctaaactaagaattgttgatatagataagaaaacatgtttatcc
ttttttatcgacgtgaataatgagctgcctggcaaatttactcttgataagaatggctat
attgctgaagaggaacctccattatcgcttgttttttctctgtttgaagggattaaaata
gcagactcacactccctttggttaaaagaaagactatgtatatccttacttgccatgttc
aaaaaacgcgaaagtgtaaattcatttatactaacaaatataaatacatttacctgtaaa
attactggaataatcagttttaatattgagcggcaatggcatttaaaagatattgcggaa
ttgatttatacgagtgaaagtttaataaaaaaaagattaagggatgaaggaacgtcattt
actgaaatattgagagatactaggatgaggtatgcaaaaaaactcataacttcaaactct
tattctatcaatgtcgtagcccagaaatgtggctataacagtacttcatatttcatatgt
gcatttaaagattattatggtgtcacgccatctcattattttgagaaaataatcggcgtc
acagatggaataaacaaaacaattgactga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:249
Protein Molecular Weight:28763
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>HTH-type transcriptional regulator AppY
MDYVCSVVFICQSFDLIINRRVISFKKNSLFIVSDKIRRELPVCPSKLRIVDIDKKTCLS
FFIDVNNELPGKFTLDKNGYIAEEEPPLSLVFSLFEGIKIADSHSLWLKERLCISLLAMF
KKRESVNSFILTNINTFTCKITGIISFNIERQWHLKDIAELIYTSESLIKKRLRDEGTSF
TEILRDTRMRYAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFEKIIGV
TDGINKTID
References
External Links:
ResourceLink
Uniprot ID:P05052
Uniprot Name:APPY_ECOLI
CCDB:APPY_ECOLI
General Reference:Not Available