| Identification |
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| Name: | DNA-3-methyladenine glycosylase 2 |
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| Synonyms: | Not Available |
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| Gene Name: | alkA |
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| Enzyme Class: | |
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| Biological Properties |
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| General Function: | DNA repair |
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| Specific Function: | Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2-methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| alkylbase DNA N-glycosylase activity | | base-excision repair | | cellular response to DNA damage stimulus | | cytoplasm | | DNA dealkylation involved in DNA repair | | DNA repair | | DNA-3-methyladenine glycosylase activity | | DNA-3-methylguanine glycosylase activity | | DNA-7-methyladenine glycosylase activity | | DNA-7-methylguanine glycosylase activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >849
atgtataccctgaactggcagccgccgtatgactggtcgtggatgttgggatttctcgcc
gcccgtgcggtgagcagtgtggaaacggtcgcggacagttattatgcccgtagtctggcg
gtgggcgaatatcgcggcgtggtgactgctattccggatatagcccgccatactctgcac
ataaatttaagtgcaggtttagaacctgttgccgcagagtgtctggcgaaaatgagccgc
ctgtttgatctgcaatgtaacccacaaattgttaacggtgcgttgggcaggttaggcgcg
gcgcggcccggattgcgtttacccggctgtgttgatgcttttgagcagggcgtgcgggcg
attttaggccaactggtgagcgtggcgatggcggcaaaattgaccgccagagtggcacag
ctttatggcgaacggctggatgattttccggagtatatctgcttcccgacgcctcagcgg
ctggcagcagcagacccgcaggcattaaaagcgttaggtatgccgttgaaacgggcagag
gcgctgattcatctggcaaatgcggcgctggagggcaccttaccaatgacaataccgggc
gatgtggagcaggcgatgaaaacgctgcaaacttttccgggtatcgggcgctggacggcg
aattattttgctttgcgtggctggcaggcgaaagatgttttcctgccggatgattatctg
attaaacagcgatttccgggaatgacaccggcgcaaatccgccgttatgccgagcgctgg
aagccctggcgttcttatgcgctgttgcatatctggtatacggaaggctggcaaccagac
gaagcatga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 282 |
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| Protein Molecular Weight: | 31392 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1DIZ |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >DNA-3-methyladenine glycosylase 2
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLH
INLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRA
ILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAE
ALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYL
IKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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