Identification
Name:Methyl-accepting chemotaxis protein I
Synonyms:Not Available
Gene Name:tsr
Enzyme Class:Not Available
Biological Properties
General Function:signal transduction
Specific Function:Receptor for the attractant L-serine and related amino acids. Is also responsible for chemotaxis away from a wide range of repellents, including leucine, indole, and weak acids.Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell motility
chemotaxis
integral component of plasma membrane
protein histidine kinase binding
response to amino acid
signal transduction
transmembrane signaling receptor activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1656
atgttaaaacgtatcaaaattgtgaccagcttactgctggttttggccgtttttggcctt
ttacaactgacatcaggcggtctgttctttaatgccttaaagaatgacaaagaaaatttc
actgttttacaaaccattcgccagcagcaatccacgctgaatggcagctgggtcgcgttg
ttgcagacgcgtaacaccctcaaccgcgcgggtatccgctacatgatggatcagaataat
attggtagcggttcaaccgttgctgagctgatggagagtgccagtatttcgctgaaacag
gcggaaaaaaactgggcggattacgaagcgttgccgcgtgacccgcgtcagagcaccgcc
gcagcggcagagatcaaacgtaattacgatatttatcacaatgcgctggcggagctgatc
caactgttaggtgcaggcaaaatcaacgagttctttgatcagccgacccagggatatcag
gacggtttcgagaagcagtatgtggcttacatggagcaaaacgatcggctccatgatatc
gccgtcagcgataacaatgcctcctacagccaggcgatgtggattctggtgggcgtgatg
atcgtcgtactggcggtcatcttcgccgtctggttcggtattaaagcctcgctggtagcg
ccaatgaatcgcctgattgacagcattcgtcatattgcaggcggcgatctggtgaaaccg
attgaggtggatggctctaatgagatggggcaactggcagagagtttgcgccatatgcag
ggagagctgatgcgtaccgtcggtgatgtgcgcaacggggccaatgccatctatagcggt
gccagcgaaatcgccaccggcaataacgatctctcttcgcgcaccgagcaacaggccgct
tcgctggaagagacggcagccagcatggagcaactgaccgcaacggtgaagcagaacgcc
gaaaatgcgcgccaggccagccatctggcgttaagtgcttctgaaacggcgcaacgcggc
ggtaaagtggtagataacgtggtgcagactatgcgcgatatctccaccagttcgcagaaa
atcgccgatattatcagcgtaattgacggcattgccttccagaccaatattctggctttg
aacgcggcggttgaggctgcgcgtgcgggtgagcaagggcgcggttttgcggtggtcgcg
ggagaagtgcgtaatctggcccagcgcagcgcccaggcggctcgtgaaattaaaagcctg
attgaagactcggtggggaaagtggatgttggctctacgctggtcgaaagcgccggggaa
acaatggcggagattgtcagcgccgtgacccgcgtgacggacattatgggcgaaattgct
tctgcttctgatgagcagagccgtggtatcgatcaggttggcttagcggttgctgagatg
gaccgggtaactcaacagaacgccgcgctggtggaagagtctgccgctgccgccgccgcg
ctggaagagcaggccagtcgcctgaccgaagcagtggcagtgttccggattcagcaacag
cagcgtgaaacatcggctgtggtaaaaaccgtgacgccagctgcgccgcgtaaaatggcc
gtggcagatagcgaggagaactgggaaacattttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:551
Protein Molecular Weight:59442
Protein Theoretical pI:Not Available
PDB File:1QU7
Signaling Regions:Not Available
Transmembrane Regions:
  • 7-30
  • 191-210
Protein Sequence:
>Methyl-accepting chemotaxis protein I
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQSTLNGSWVAL
LQTRNTLNRAGIRYMMDQNNIGSGSTVAELMESASISLKQAEKNWADYEALPRDPRQSTA
AAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLHDI
AVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAA
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSL
IEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQRETSAVVKTVTPAAPRKMA
VADSEENWETF
References
External Links:
ResourceLink
Uniprot ID:P02942
Uniprot Name:MCP1_ECOLI
PDB ID:1QU7
CCDB:MCP1_ECOLI
General Reference:Not Available