Identification
Name:RNA polymerase sigma factor RpoD
Synonyms:Not Available
Gene Name:rpoD
Enzyme Class:Not Available
Biological Properties
General Function:transcription initiation from bacterial-type RNA polymerase promoter
Specific Function:Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Preferentially transcribes genes associated with fast growth, such as ribosomal operons, other protein-synthesis related genes, rRNA- and tRNA-encoding genes and prfB.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA binding
response to heat
sequence-specific DNA binding transcription factor activity
sigma factor activity
transcription initiation from bacterial-type RNA polymerase promoter
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1842
atggagcaaaacccgcagtcacagctgaaacttcttgtcacccgtggtaaggagcaaggc
tatctgacctatgccgaggtcaatgaccatctgccggaagatatcgtcgattcagatcag
atcgaagacatcatccaaatgatcaacgacatgggcattcaggtgatggaagaagcaccg
gatgccgatgatctgatgctggctgaaaacaccgcggacgaagatgctgccgaagccgcc
gcgcaggtgctttccagcgtggaatctgaaatcgggcgcacgactgacccggtacgcatg
tacatgcgtgaaatgggcaccgttgaactgttgacccgcgaaggcgaaattgacatcgct
aagcgtattgaagacgggatcaaccaggttcaatgctccgttgctgaatatccggaagcg
atcacctatctgctggaacagtacgatcgtgttgaagcagaagaagcgcgtctgtccgat
ctgatcaccggctttgttgacccgaacgcagaagaagatctggcacctaccgccactcac
gtcggttctgagctttcccaggaagatctggacgatgacgaagatgaagacgaagaagat
ggcgatgacgacagcgccgatgatgacaacagcatcgacccggaactggctcgcgaaaaa
tttgcggaactacgcgctcagtacgttgtaacgcgtgacaccatcaaagcgaaaggtcgc
agtcacgctaccgctcaggaagagatcctgaaactgtctgaagtattcaaacagttccgc
ctggtgccgaagcagtttgactacctggtcaacagcatgcgcgtcatgatggaccgcgtt
cgtacgcaagaacgtctgatcatgaagctctgcgttgagcagtgcaaaatgccgaagaaa
aacttcattaccctgtttaccggcaacgaaaccagcgatacctggttcaacgcggcaatt
gcgatgaacaagccgtggtcggaaaaactgcacgatgtctctgaagaagtgcatcgcgcc
ctgcaaaaactgcagcagattgaagaagaaaccggcctgaccatcgagcaggttaaagat
atcaaccgtcgtatgtccatcggtgaagcgaaagcccgccgtgcgaagaaagagatggtt
gaagcgaacttacgtctggttatttctatcgctaagaaatacaccaaccgtggcttgcag
ttccttgacctgattcaggaaggcaacatcggtctgatgaaagcggttgataaattcgaa
taccgccgtggttacaagttctccacctacgcaacctggtggatccgtcaggcgatcacc
cgctctatcgcggatcaggcgcgcaccatccgtattccggtgcatatgattgagaccatc
aacaagctcaaccgtatttctcgccagatgctgcaagagatgggccgtgaaccgacgccg
gaagaactggctgaacgtatgctgatgccggaagacaagatccgcaaagtgctgaagatc
gccaaagagccaatctccatggaaacgccgatcggtgatgatgaagattcgcatctgggg
gatttcatcgaggataccaccctcgagctgccgctggattctgcgaccaccgaaagcctg
cgtgcggcaacgcacgacgtgctggctggcctgaccgcgcgtgaagcaaaagttctgcgt
atgcgtttcggtatcgatatgaacaccgactacacgctggaagaagtgggtaaacagttc
gacgttacccgcgaacgtatccgtcagatcgaagcgaaggcgctgcgcaaactgcgtcac
ccgagccgttctgaagtgctgcgtagcttcctggacgattaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:613
Protein Molecular Weight:70262
Protein Theoretical pI:Not Available
PDB File:1SIG
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>RNA polymerase sigma factor RpoD
MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVMEEAP
DADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIA
KRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLITGFVDPNAEEDLAPTATH
VGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAREKFAELRAQYVVTRDTIKAKGR
SHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKK
NFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKD
INRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFE
YRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTP
EELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESL
RAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRH
PSRSEVLRSFLDD
References
External Links:
ResourceLink
Uniprot ID:P00579
Uniprot Name:RPOD_ECOLI
PDB ID:1SIG
CCDB:RPOD_ECOLI
General Reference:Not Available