Identification
Name:Transcriptional regulator LsrR
Synonyms:Not Available
Gene Name:lsrR
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
carbohydrate binding
cytoplasm
DNA binding
regulation of transcription, DNA-templated
response to heat
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>954
atgacaatcaacgattcggcaatttcagaacagggaatgtgtgaagaagaacaggtcgcg
cggatcgcgtggttttactatcacgacgggctgacccagagcgagatcagcgatcgtctc
ggcctgacacgtttgaaagtgtcgcgattgctggagaaagggcatcagtccggcattatt
cgcgtacagattaattctcgctttgaaggctgtctggaatatgaaactcaattacgtcgt
cagttttcgctgcaacatgtccgggtgatccctgggcttgcggatgctgatgtcggtggg
cgactggggataggcgcggcgcatatgttgatgagtttacttcaaccacaacagatgctg
gcgattggttttggcgaggcaaccatgaatacgctgcaacgcttaagtggttttatttcg
tcacagcaaattcgcctggtcacgctctccggtggcgtcggttcttatatgacgggaatc
gggcagcttaacgcggcgtgcagtgtgaatattattccggctccgttgcgggcatcctcc
gctgacattgcccgtacgctaaaaaatgaaaattgcgtcaaagatgttctgttagccgcg
caagcagcggatgtggcgattgtcggcattggtgctgtgagtcaacaggacgatgcgaca
atcattcgctccggttatatcagccagggcgaacagttaatgattggccgaaaaggggcg
gttggcgacattttaggctacttttttgatgcaaaaggtgacgttgtcacgaatatcaaa
atacataacgaactgattggcttacctttaagcgcgctgaagaccatacccgtccgggtt
ggcgtggcagggggagaaaataaagccgaagcaattgccgctgcaatgaaaggcggttat
atcaacgcactggttaccgatcaggacacagcagcggcgattttacgtagttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:317
Protein Molecular Weight:33796
Protein Theoretical pI:Not Available
PDB File:4GO1
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Transcriptional regulator LsrR
MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGII
RVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQML
AIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASS
ADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGY
INALVTDQDTAAAILRS
References
External Links:
ResourceLink
Uniprot ID:P76141
Uniprot Name:LSRR_ECOLI
PDB ID:4GO1
CCDB:LSRR_ECOLI
General Reference:Not Available