ECMDB: Probable phospholipid ABC transporter permease protein mlaE (P64608)

Identification

Name:

Probable phospholipid ABC transporter permease protein mlaE

Synonyms:

Not Available

Gene Name:

mlaE

Enzyme Class:

Not Available

Biological Properties

General Function:

Secondary metabolites biosynthesis, transport and catabolism

Specific Function:

Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane

Cellular Location:

Cell inner membrane; Multi-pass membrane protein

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Not Available

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>783 bp
ATGKCTGGMGCATTTKCCGGTGCCTTTGCCACCGGACACCTGATTTCACTGGCTGATGAG
TGGAGTTCCGTGAATGMCCGTCTGAAACAGGCGTMGCAGTCATCTGATGAATTTTCGTCA
KCACAGAAAGTGCTGATGGATATCAGTCAGCGGACAGGKWCCGCTTTTTCGGATAATSCG
GCCCTGTTTGYCCGCTCGGCAGCCTCAATGCGTGAATATGGTTACAGTGCTGATGATGTG
CTGAAGGTGACGGAGGCCATTTCCACGGGGCTGAAAATCTCCGGTGCCAGTACGGCTGAG
GCGGGTTCGGTGATCACCCAGTTCAGCCAGGCGCTGGCACAGGGTGTGTTGCGCGGTGAG
GAATTTAATTCGGTCAATGAAAGTGGTGACCGGATCGTACGTGCACTGGCTGCGGGTATG
GGCGTGGCCCGTAAAGATCTGAAGGCGATGGCGGACGATGGTCAACTGACGGCGGATAAA
GTCGTTCCTGCGTTAATCAGCCAGCTGGAGGTATTGCGTGATGAATACGCGGCCATGCCG
GAAACGGTCTCTGACGGGATCACAAAGGTGGAAAACGCCTTTATGGCCTGGGTGGGTGGT
GCGAATGAGGCCAGCGGGGTGACGAAAACGCTCTCCGGCGTGCTGAACGGTGTTGCCGGA
CAGATTGATAATGTGGCAACAGCCCGTGGGGGCACTGGTTGCCGTCGGGGTTGCCCGGTA
CTTTGGCAATATGGCCTCCGGAGCGATGTCTGCCACGGCAGGACTTGTGACGGCTGCACG
TAA

Protein Properties

Pfam Domain Function:

DUF140 (PF02405 )

Protein Residues:

260

Protein Molecular Weight:

27863

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

51-71
89-109
148-168
199-219
239-259

Protein Sequence:

>Probable phospholipid ABC transporter permease protein mlaE
MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLLVRQLYNVGVLSMLIIV
VSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEI
GLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTVIFVAVGIWGGSLVGVSWKGI
DSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISLFNGYDAIPTSAGISRATTRTVV
HSSLAVLGLDFVLTALMFGN

References

External Links:

Resource	Link
Uniprot ID:	P64608
Uniprot Name:	MLAE_ECO57
GenBank Gene ID:	AE005174
Genebank Protein ID:	12514217
EchoBASE ID:	EB2652
CCDB:	MLAE_ECO57

General Reference:

Hayashi, T., Makino, K., Ohnishi, M., Kurokawa, K., Ishii, K., Yokoyama, K., Han, C. G., Ohtsubo, E., Nakayama, K., Murata, T., Tanaka, M., Tobe, T., Iida, T., Takami, H., Honda, T., Sasakawa, C., Ogasawara, N., Yasunaga, T., Kuhara, S., Shiba, T., Hattori, M., Shinagawa, H. (2001). "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." DNA Res 8:11-22. Pubmed: 11258796
Perna, N. T., Plunkett, G. 3rd, Burland, V., Mau, B., Glasner, J. D., Rose, D. J., Mayhew, G. F., Evans, P. S., Gregor, J., Kirkpatrick, H. A., Posfai, G., Hackett, J., Klink, S., Boutin, A., Shao, Y., Miller, L., Grotbeck, E. J., Davis, N. W., Lim, A., Dimalanta, E. T., Potamousis, K. D., Apodaca, J., Anantharaman, T. S., Lin, J., Yen, G., Schwartz, D. C., Welch, R. A., Blattner, F. R. (2001). "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Nature 409:529-533. Pubmed: 11206551