Identification
Name:Lipoprotein NlpE
Synonyms:Not Available
Gene Name:nlpE
Enzyme Class:Not Available
Biological Properties
General Function:regulation of cell-substrate adhesion
Specific Function:Involved in copper homeostasis. Could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes. When overproduced induces degP through the activation of the two-component system CpxA/CpxR.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
  • Cationic antimicrobial peptide (CAMP) resistance eco01503
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell outer membrane
regulation of cell-substrate adhesion
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>711
atggtgaaaaaagcgatagtgacagcgatggctgtaatcagcctctttactctgatggga
tgtaataatcgggccgaagtcgatacgctttctccggcgcaggctgccgaactgaaaccg
atgccgcaaagttggcgcggcgtgctgccgtgtgccgattgcgaaggaatcgaaacctct
ctgttcctcgaaaaagacggaacatgggtgatgaatgagcgttatctcggtgctcgtgaa
gaaccttcctccttcgcttcctacggtacatgggcgcgaaccgctgacaagctggtatta
accgacagcaaaggtgaaaagtcatattatcgggcgaaaggcgatgcgctggagatgctc
gatcgtgaaggcaatccgattgaatcgcagttcaactatacgctggaagcggcacaatcc
agtttacctatgacgccgatgaccctgcggggcatgtatttttatatggctgatgcggcg
accttcactgattgcgcgaccggaaaacgtttcatggtagcgaataacgcagagctggag
cgtagctacctggctgcgcgcggtcacagtgaaaaaccggtgttactgtcagtagaaggt
cactttacgcttgagggtaatccggataccggtgcgccgactaaagtattggcacccgat
acggcagggaaattttaccccaaccaggattgcagtagtttggggcagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:236
Protein Molecular Weight:25844
Protein Theoretical pI:Not Available
PDB File:2Z4H
Signaling Regions:
  • 1-20
Transmembrane Regions:Not Available
Protein Sequence:
>Lipoprotein NlpE
MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQSWRGVLPCADCEGIETS
LFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTDSKGEKSYYRAKGDALEML
DREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAATFTDCATGKRFMVANNAELE
RSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLAPDTAGKFYPNQDCSSLGQ
References
External Links:
ResourceLink
Uniprot ID:P40710
Uniprot Name:NLPE_ECOLI
PDB ID:2Z4H
CCDB:NLPE_ECOLI
General Reference:Not Available