ECMDB: Putative arsenate reductase (P0CF87)

Identification

Name:

Putative arsenate reductase

Synonyms:

Arsenical pump modifier

Gene Name:

yfjU

Enzyme Class:

1.20.4.1

Biological Properties

General Function:

Inorganic ion transport and metabolism

Specific Function:

Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Complex Reactions:

1.0

1.0glutaredoxin

→

1.0

1.0glutaredoxin disulfide

1.0

1.0Arsenate + 1.0glutaredoxin → 1.0Arsenite + 1.0glutaredoxin disulfide + 1.0Water
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB21394	Arsenate	MetaboCard
ECMDB21309	Arsenite	MetaboCard
ECMDB00494	Water	MetaboCard

GO Classification:

Not Available

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

Not Available

Protein Properties

Pfam Domain Function:

ArsC (PF03960 )

Protein Residues:

104

Protein Molecular Weight:

11823

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

None

Protein Sequence:

>Putative arsenate reductase
MSNITIYHNPACGTSRNTLEMLHNNGNEPTIINYLDMPPTRDELIKLISDIFSDKIIECI
REQCHLMPALSLNVIGHVDIRSIHSYLFNFNEKVSPSHGFIKNG

References

External Links:

Resource	Link
Uniprot ID:	P0CF87
Uniprot Name:	ARSCL_ECOLI
CCDB:	ARSCL_ECOLI

General Reference:

Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837