2.0 2015-09-08 19:02:15 -0600 2015-12-09 14:08:43 -0700 ECMDB24339 M2MDB006456 DG(17:0/16:1(9Z)/0:0) DG(17:0/16:1(9Z)/0:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. DG(17:0/16:1(9Z)/0:0) is also a substrate of diacylglycerol kinase. It is involved in the phospholipid metabolic pathway. C36H68O5 580.935 580.50667529 (2S)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl heptadecanoate (2S)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl heptadecanoate [H][C@](O)(COC(=O)CCCCCCCCCCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCC InChI=1S/C36H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(39)41-33-34(37)32-40-35(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h14,16,34,37H,3-13,15,17-33H2,1-2H3/b16-14-/t34-/m1/s1 WBGKIWKQHNNYRR-CVBYVTFXSA-N logp 10.00 ALOGPS logs -7.49 ALOGPS solubility 1.88e-05 g/l ALOGPS logp 12.09 ChemAxon pka_strongest_acidic 13.63 ChemAxon pka_strongest_basic -3.4 ChemAxon iupac (2S)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl heptadecanoate ChemAxon average_mass 580.935 ChemAxon mono_mass 580.50667529 ChemAxon smiles [H][C@](O)(COC(=O)CCCCCCCCCCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCC ChemAxon formula C36H68O5 ChemAxon inchi InChI=1S/C36H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(39)41-33-34(37)32-40-35(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h14,16,34,37H,3-13,15,17-33H2,1-2H3/b16-14-/t34-/m1/s1 ChemAxon inchikey WBGKIWKQHNNYRR-CVBYVTFXSA-N ChemAxon polar_surface_area 72.83 ChemAxon refractivity 173.42 ChemAxon polarizability 76.65 ChemAxon rotatable_bond_count 34 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon phospholipid biosynthesis (CL(17:0/16:1(9Z)/14:0/14:0)) Phospholipids are membrane components in E. coli. The major phospholipids of E. coli are phosphatidylethanolamine, phosphatidylglycerol and cardiolipin. All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions. The reaction starts from a glycerone phosphate (dihydroxyacetone phosphate) produced in glycolysis. The glycerone phosphate is transformed to a sn-glycerol 3-phosphate (glycerol 3 phosphate) by NADPH driven glycerol-3-phosphate dehydrogenase. Sn-glycerol 3-phosphate is transformed to a 1-acyl-sn-glycerol 3-phosphate(1-oleyl-2-lyso-phosphatidate , 1-palmitoylglycerol 3-phosphate , 1-stearoyl-sn-glycerol 3-phosphate). This can be achieve by a sn-glycerol-3-phosphate 1-0-acyltransferase that interacts either with a long-chain acyl-CoA or with an acyl-[acp]. The 1-acyl-sn-glycerol 3-phosphate is transformed into a 1,2-diacyl-sn-glycerol 3-phosphate through a 1-acylglycerol-3-phosphate O-acyltransferase. This compound is then converted into a CPD-diacylglycerol through a CTP (phosphatidate cytididyltransferase. CPD-diacylglycerol can be transformed either to a L-1-phosphatidylserine or a L-1-phosphatidylglycerol-phosphate through a phosphatidylserine synthase or a phosphatidylglycerophosphate synthase respectively. The L-1-phosphatidylserine transforms into L-1-phosphatidylethanolamine through a phosphatidylserine decarboxylase, o the other hand L-1-phosphatidylglycerol-phosphate gets transformed into a L-1-phosphatidyl-glycerol through a phosphatidylglycerophosphatase. These 2 products combines produce a cardiolipin and a ethanolamine. The L-1 phosphatidyl-glycerol can also interact with cardiolipin synthase resulting in a glycerol and a cardiolipin. PW001963 Metabolic phospholipid biosynthesis (CL(17:0/16:1(9Z)/16:0/16:0)) Phospholipids are membrane components in E. coli. The major phospholipids of E. coli are phosphatidylethanolamine, phosphatidylglycerol and cardiolipin. All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions. The reaction starts from a glycerone phosphate (dihydroxyacetone phosphate) produced in glycolysis. The glycerone phosphate is transformed to a sn-glycerol 3-phosphate (glycerol 3 phosphate) by NADPH driven glycerol-3-phosphate dehydrogenase. Sn-glycerol 3-phosphate is transformed to a 1-acyl-sn-glycerol 3-phosphate(1-oleyl-2-lyso-phosphatidate , 1-palmitoylglycerol 3-phosphate , 1-stearoyl-sn-glycerol 3-phosphate). This can be achieve by a sn-glycerol-3-phosphate 1-0-acyltransferase that interacts either with a long-chain acyl-CoA or with an acyl-[acp]. The 1-acyl-sn-glycerol 3-phosphate is transformed into a 1,2-diacyl-sn-glycerol 3-phosphate through a 1-acylglycerol-3-phosphate O-acyltransferase. This compound is then converted into a CPD-diacylglycerol through a CTP (phosphatidate cytididyltransferase. CPD-diacylglycerol can be transformed either to a L-1-phosphatidylserine or a L-1-phosphatidylglycerol-phosphate through a phosphatidylserine synthase or a phosphatidylglycerophosphate synthase respectively. The L-1-phosphatidylserine transforms into L-1-phosphatidylethanolamine through a phosphatidylserine decarboxylase, o the other hand L-1-phosphatidylglycerol-phosphate gets transformed into a L-1-phosphatidyl-glycerol through a phosphatidylglycerophosphatase. These 2 products combines produce a cardiolipin and a ethanolamine. The L-1 phosphatidyl-glycerol can also interact with cardiolipin synthase resulting in a glycerol and a cardiolipin. PW001964 Metabolic Specdb::CMs 1087394 Specdb::NmrOneD 332318 Specdb::NmrOneD 332319 Specdb::NmrOneD 332320 Specdb::NmrOneD 332321 Specdb::NmrOneD 332322 Specdb::NmrOneD 332323 Specdb::NmrOneD 332324 Specdb::NmrOneD 332325 Specdb::NmrOneD 332326 Specdb::NmrOneD 332327 Specdb::NmrOneD 332328 Specdb::NmrOneD 332329 Specdb::NmrOneD 332330 Specdb::NmrOneD 332331 Specdb::NmrOneD 332332 Specdb::NmrOneD 332333 Specdb::NmrOneD 332334 Specdb::NmrOneD 332335 Specdb::NmrOneD 332336 Specdb::NmrOneD 332337 Specdb::MsMs 1328785 Specdb::MsMs 1328786 Specdb::MsMs 1328787 Specdb::MsMs 1443115 Specdb::MsMs 1443116 Specdb::MsMs 1443117 Yurtsever D. (2007). Fatty acid methyl ester profiling of Enterococcus and Esherichia coli for microbial source tracking. M.sc. Thesis. Villanova University: U.S.A Phosphatidate cytidylyltransferase P0ABG1 CDSA_ECOLI cdsA http://ecmdb.ca/proteins/P0ABG1.xml DG(17:0/16:1(9Z)/0:0) + Cytidine triphosphate + Hydrogen ion > CDP-DG(17:0/16:1(9Z)) + Pyrophosphate PW_R005519