Fe2+ (ECMDB23899) (M2MDB005697)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes (3)XML
Proteins (792)
Record Information
Version2.0
Creation Date2015-06-11 11:43:40 -0600
Update Date2015-07-23 12:07:31 -0600
Secondary Accession Numbers
  • ECMDB23899
Identification
Name:Fe2+
Description
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms:
  • Fe(II)
  • Ferrous ion
  • Iron(2+)
Chemical Formula:Fe
Weight:Average: 55.845
Monoisotopic: 55.934942133
InChI Key:CWYNVVGOOAEACU-UHFFFAOYSA-N
InChI:InChI=1S/Fe/q+2
CAS number:Not Available
IUPAC Name:lambda2-iron(2+) ion
Traditional IUPAC Name:lambda2-iron(2+) ion
SMILES:[Fe++]
Chemical Taxonomy
Description belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous transition metal compounds
Sub ClassNot Available
Direct ParentHomogeneous transition metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous transition metal
Molecular FrameworkNot Available
External Descriptors
Physical Properties
State:Not Available
Charge:2
Melting point:Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
logP-0.77ChemAxon
pKa (Strongest Acidic)4.58ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability1.78 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations:Cytoplasm
Reactions:
Oxygen + 4 Fe2+ + 4 Hydrogen ion + 4 Fe2+ <>4 Fe3+ +2 Water
Protoporphyrin IX + Fe2+ <> Heme +2 Hydrogen ion + Fe2+
Oxygen + 4 Fe2+ + 4 Hydrogen ion <>4 Fe3+ +2 Water
Protoporphyrin IX + Fe2+ <> Heme +2 Hydrogen ion
Oxygen + 4 Fe2+ + 4 Hydrogen ion <>4 Fe3+ +2 Water
SMPDB Pathways:Not Available
KEGG Pathways:
EcoCyc Pathways:Not Available
Concentrations
Not Available
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0a4i-9000000000-af3e7aec4f5bd9668683View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0a4i-9000000000-af3e7aec4f5bd9668683View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0a4i-9000000000-af3e7aec4f5bd9668683View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0udi-9000000000-3335fec4c3184739b75eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udi-9000000000-3335fec4c3184739b75eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udi-9000000000-3335fec4c3184739b75eView in MoNA
References
References:Not Available
Synthesis Reference:Not Available
Material Safety Data Sheet (MSDS)Not Available
External Links:
ResourceLink
CHEBI ID29033
HMDB IDHMDB0015531
Pubchem Compound ID27284
Kegg IDC14818
ChemSpider ID25394
Wikipedia IDIron
BioCyc IDNot Available

Enzymes

Protein Details
1. Siroheme synthase
General function:
Involved in methyltransferase activity
Specific function:
Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme
Gene Name:
cysG
Uniprot ID:
P0AEA8
Molecular weight:
49951
Reactions
S-adenosyl-L-methionine + uroporphyrinogen III = S-adenosyl-L-homocysteine + precorrin-1.
S-adenosyl-L-methionine + precorrin-1 = S-adenosyl-L-homocysteine + precorrin-2.
Precorrin-2 + NAD(+) = sirohydrochlorin + NADH.
Siroheme + 2 H(+) = sirohydrochlorin + Fe(2+).
Protein Details
2. Ferrochelatase
General function:
Involved in ferrochelatase activity
Specific function:
Catalyzes the ferrous insertion into protoporphyrin IX
Gene Name:
hemH
Uniprot ID:
P23871
Molecular weight:
35884
Reactions
Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
Protein Details
3. Bacterioferritin
General function:
Inorganic ion transport and metabolism
Specific function:
May perform analogous functions in iron detoxification and storage to that of animal ferritins
Gene Name:
bfr
Uniprot ID:
P0ABD3
Molecular weight:
18495
Reactions
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.