2.0 2012-10-10 13:28:15 -0600 2015-12-09 14:08:31 -0700 ECMDB23292 M2MDB003682 DG(16:1(9Z)/18:0/0:0) DG(16:1(9Z)/18:0/0:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. DG(16:1(9Z)/18:0/0:0) is also a substrate of diacylglycerol kinase. It is involved in the phospholipid metabolic pathway. 1-(9Z-hexadecenoyl)-2-octadecanoyl-sn-glycerol 1-palmitoleoyl-2-stearoyl-sn-glycerol DAG(16:1/18:0) DAG(16:1n7/18:0) DAG(16:1w7/18:0) DAG(34:1) DG(16:1/18:0) DG(16:1n7/18:0) DG(16:1w7/18:0) DG(34:1) Diacylglycerol Diacylglycerol(16:1/18:0) Diacylglycerol(16:1n7/18:0) Diacylglycerol(16:1w7/18:0) Diacylglycerol(34:1) Diglyceride C37H70O5 594.962 594.522325354 (2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl octadecanoate (2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl octadecanoate [H][C@@](O)(COC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCC InChI=1S/C37H70O5/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(40)42-34-35(38)33-41-36(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h14,16,35,38H,3-13,15,17-34H2,1-2H3/b16-14-/t35-/m0/s1 PRTSHZSSLZAYMU-BSNNDZOISA-N Membrane logp 10.13 ALOGPS logs -7.54 ALOGPS solubility 1.70e-05 g/l ALOGPS logp 12.53 ChemAxon pka_strongest_acidic 13.63 ChemAxon pka_strongest_basic -3.4 ChemAxon iupac (2R)-3-[(9Z)-hexadec-9-enoyloxy]-2-hydroxypropyl octadecanoate ChemAxon average_mass 594.962 ChemAxon mono_mass 594.522325354 ChemAxon smiles [H][C@@](O)(COC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCC ChemAxon formula C37H70O5 ChemAxon inchi InChI=1S/C37H70O5/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(40)42-34-35(38)33-41-36(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h14,16,35,38H,3-13,15,17-34H2,1-2H3/b16-14-/t35-/m0/s1 ChemAxon inchikey PRTSHZSSLZAYMU-BSNNDZOISA-N ChemAxon polar_surface_area 72.83 ChemAxon refractivity 178.02 ChemAxon polarizability 78.78 ChemAxon rotatable_bond_count 35 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon phospholipid biosynthesis (PE(16:1(9Z)/18:0)) Phospholipids are membrane components in E. coli. The major phospholipids of E. coli are phosphatidylethanolamine, phosphatidylglycerol and cardiolipin. All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions. The reaction starts from a glycerone phosphate (dihydroxyacetone phosphate) produced in glycolysis. The glycerone phosphate is transformed to a sn-glycerol 3-phosphate (glycerol 3 phosphate) by NADPH driven glycerol-3-phosphate dehydrogenase. Sn-glycerol 3-phosphate is transformed to a 1-acyl-sn-glycerol 3-phosphate(1-oleyl-2-lyso-phosphatidate , 1-palmitoylglycerol 3-phosphate , 1-stearoyl-sn-glycerol 3-phosphate). This can be achieve by a sn-glycerol-3-phosphate 1-0-acyltransferase that interacts either with a long-chain acyl-CoA or with an acyl-[acp]. The 1-acyl-sn-glycerol 3-phosphate is transformed into a 1,2-diacyl-sn-glycerol 3-phosphate through a 1-acylglycerol-3-phosphate O-acyltransferase. This compound is then converted into a CPD-diacylglycerol through a CTP (phosphatidate cytididyltransferase. CPD-diacylglycerol can be transformed either to a L-1-phosphatidylserine or a L-1-phosphatidylglycerol-phosphate through a phosphatidylserine synthase or a phosphatidylglycerophosphate synthase respectively. The L-1-phosphatidylserine transforms into L-1-phosphatidylethanolamine through a phosphatidylserine decarboxylase, o the other hand L-1-phosphatidylglycerol-phosphate gets transformed into a L-1-phosphatidyl-glycerol through a phosphatidylglycerophosphatase. These 2 products combines produce a cardiolipin and a ethanolamine. The L-1 phosphatidyl-glycerol can also interact with cardiolipin synthase resulting in a glycerol and a cardiolipin. PW001758 Metabolic Specdb::CMs 1087935 Specdb::MsMs 1325941 Specdb::MsMs 1325942 Specdb::MsMs 1325943 Specdb::MsMs 1440289 Specdb::MsMs 1440290 Specdb::MsMs 1440291 HMDB07129 Yurtsever D. (2007). Fatty acid methyl ester profiling of Enterococcus and Esherichia coli for microbial source tracking. M.sc. Thesis. Villanova University: U.S.A Phosphatidylglycerophosphatase B P0A924 PGPB_ECOLI pgpB http://ecmdb.ca/proteins/P0A924.xml Phosphatidate cytidylyltransferase P0ABG1 CDSA_ECOLI cdsA http://ecmdb.ca/proteins/P0ABG1.xml Diacylglycerol kinase P0ABN1 KDGL_ECOLI dgkA http://ecmdb.ca/proteins/P0ABN1.xml DG(16:1(9Z)/18:0/0:0) + Hydrogen ion + Cytidine triphosphate + DG(16:1(9Z)/18:0/0:0) > CDP-DG(16:1(9Z)/18:0) + Pyrophosphate PW_R004708