Record Information |
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Version | 2.0 |
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Creation Date | 2012-08-09 09:25:05 -0600 |
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Update Date | 2015-06-03 17:21:36 -0600 |
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Secondary Accession Numbers | |
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Identification |
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Name: | 2,3-Dihydroxyisovaleric acid |
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Description | 2,3-dihydroxyisovaleric acid (or 2,3-Dihydroxy-3-methylbutanoate) is invovled in branched chain amino acid biosynthesis. It is a substrate for Ketol-acid reductoisomerase (ilvC). This enzyme catalyzes the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH. |
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Structure | |
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Synonyms: | - 2,3-Dihydroxy-3-methylbutanoate
- 2,3-Dihydroxy-3-methylbutanoic acid
- 2,3-Dihydroxy-isovalerate
- 2,3-Dihydroxy-isovaleric acid
- 2,3-Dihydroxyisovalerate
- 2,3-DIV
- a,b-Dihydroxyisovalerate
- a,b-Dihydroxyisovaleric acid
- Alpha,beta-Dihydroxyisovalerate
- Alpha,beta-Dihydroxyisovaleric acid
- α,β-Dihydroxyisovalerate
- α,β-Dihydroxyisovaleric acid
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Chemical Formula: | C5H10O4 |
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Weight: | Average: 134.1305 Monoisotopic: 134.057908808 |
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InChI Key: | JTEYKUFKXGDTEU-UHFFFAOYSA-N |
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InChI: | InChI=1S/C5H10O4/c1-5(2,9)3(6)4(7)8/h3,6,9H,1-2H3,(H,7,8) |
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CAS number: | 1756-18-9 |
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IUPAC Name: | 2,3-dihydroxy-3-methylbutanoic acid |
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Traditional IUPAC Name: | 2,3-dihydroxyisovaleric acid |
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SMILES: | CC(C)(O)C(O)C(O)=O |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as hydroxy fatty acids. These are fatty acids in which the chain bears a hydroxyl group. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Fatty Acyls |
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Sub Class | Fatty acids and conjugates |
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Direct Parent | Hydroxy fatty acids |
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Alternative Parents | |
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Substituents | - Branched fatty acid
- Methyl-branched fatty acid
- Short-chain hydroxy acid
- Hydroxy fatty acid
- Alpha-hydroxy acid
- Hydroxy acid
- Monosaccharide
- Tertiary alcohol
- 1,2-diol
- Secondary alcohol
- Carboxylic acid derivative
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Organic oxygen compound
- Carbonyl group
- Hydrocarbon derivative
- Organic oxide
- Alcohol
- Organooxygen compound
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State: | Not Available |
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Charge: | -1 |
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Melting point: | Not Available |
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Experimental Properties: | |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations: | Cytoplasm |
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Reactions: | |
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SMPDB Pathways: | Pantothenate and CoA biosynthesis | PW000828 |    |
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KEGG Pathways: | - Metabolic pathways eco01100
- Pantothenate and CoA biosynthesis ec00770
- Valine, leucine and isoleucine biosynthesis ec00290
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EcoCyc Pathways: | Not Available |
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Concentrations |
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| Not Available |
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Spectra |
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Spectra: | |
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References |
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References: | - Winder, C. L., Dunn, W. B., Schuler, S., Broadhurst, D., Jarvis, R., Stephens, G. M., Goodacre, R. (2008). "Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites." Anal Chem 80:2939-2948. Pubmed: 18331064
- Yurtsever D. (2007). Fatty acid methyl ester profiling of Enterococcus and Esherichia coli for microbial source tracking. M.sc. Thesis. Villanova University: U.S.A
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Synthesis Reference: | Not Available |
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Material Safety Data Sheet (MSDS) | Not Available |
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Links |
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External Links: | Resource | Link |
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CHEBI ID | 15689 | HMDB ID | Not Available | Pubchem Compound ID | 677 | Kegg ID | C04039 | ChemSpider ID | 657 | Wikipedia ID | Not Available | BioCyc ID | Not Available |
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