Molybdate (ECMDB21246) (M2MDB001654)
| Record Information | |||||||||||||||||||||||||||||||||||||||||||||||||
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| Version | 2.0 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Creation Date | 2012-07-30 14:55:06 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Update Date | 2015-06-03 17:21:00 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Secondary Accession Numbers |
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| Identification | |||||||||||||||||||||||||||||||||||||||||||||||||
| Name: | Molybdate | ||||||||||||||||||||||||||||||||||||||||||||||||
| Description | Molybdate is a compound containing an oxoanion with molybdenum in its highest oxidation state of 6. Molybdenum can form a very large range of such oxoanions which can be discrete structures or polymeric extended structures, although the latter are only found in the solid state.The larger oxoanions are members of group of compounds termed polyoxometalates, and because they contain only one type of metal atom are often called isopolymetalates. The discrete molybdenum oxoanions range in size from the simplest MoO42_, found in potassium molybdate up to extremely large structures found in isopoly-molybdenum blues that contain for example 154 Mo atoms. The behaviour of molybdenum is different from the other elements in group 6. Molybdate is involved in the molybdenum cofactor biosynthesis pathway. Molybdate reacts with molybdopterin-AMP to produce molybdenum cofactor, AMP, and H2O. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Structure |  | ||||||||||||||||||||||||||||||||||||||||||||||||
| Synonyms: |
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| Chemical Formula: | H2MoO4 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Weight: | Average: 161.95 Monoisotopic: 163.900716398 | ||||||||||||||||||||||||||||||||||||||||||||||||
| InChI Key: | VLAPMBHFAWRUQP-UHFFFAOYSA-L | ||||||||||||||||||||||||||||||||||||||||||||||||
| InChI: | InChI=1S/Mo.2H2O.2O/h;2*1H2;;/q+2;;;;/p-2 | ||||||||||||||||||||||||||||||||||||||||||||||||
| CAS number: | 14259-85-9 | ||||||||||||||||||||||||||||||||||||||||||||||||
| IUPAC Name: | dihydroxydioxomolybdenumbis(ylium) | ||||||||||||||||||||||||||||||||||||||||||||||||
| Traditional IUPAC Name: | dihydroxydioxomolybdenumbis(ylium) | ||||||||||||||||||||||||||||||||||||||||||||||||
| SMILES: | O[Mo](O)(=O)=O | ||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Taxonomy | |||||||||||||||||||||||||||||||||||||||||||||||||
| Description | belongs to the class of inorganic compounds known as miscellaneous molybdates. These are inorganic compounds in which the largest metallic oxoanion is molybdate, to which either no atom or a non metal atom is bonded. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Kingdom | Inorganic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
| Super Class | Mixed metal/non-metal compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
| Class | Miscellaneous mixed metal/non-metals | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sub Class | Miscellaneous metallic oxoanionic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
| Direct Parent | Miscellaneous molybdates | ||||||||||||||||||||||||||||||||||||||||||||||||
| Alternative Parents | |||||||||||||||||||||||||||||||||||||||||||||||||
| Substituents |
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| Molecular Framework | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| External Descriptors | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| Physical Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
| State: | Solid | ||||||||||||||||||||||||||||||||||||||||||||||||
| Charge: | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Melting point: | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Properties: |
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| Predicted Properties |
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| Biological Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
| Cellular Locations: | Cytoplasm | ||||||||||||||||||||||||||||||||||||||||||||||||
| Reactions: | ADP + Phosphate + 4 Hydrogen ion + Heme + Nickel(2+) + Iron chelate + Taurine + Molybdate + Magnesium + Fe3+ + Potassium + Polyamine + vitamin B12 + Sulfate + glycerol-3-phosphate + Phosphonate + D-Maltose <> Adenosine triphosphate +3 Hydrogen ion + Water Adenosine triphosphate + Water + Molybdate > ADP + Hydrogen ion + Molybdate + Phosphate Adenosine triphosphate + Water + Molybdate > ADP + Hydrogen ion + Molybdate + Phosphate 2 Hydrogen ion + Molybdate + Adenylated molybdopterin > Adenosine monophosphate + Copper + Water + Molybdopterin Adenylated molybdopterin + Molybdate <> Molybdoenzyme molybdenum cofactor + Adenosine monophosphate + Water + Molybdoenzyme molybdenum cofactor Adenosine triphosphate + Molybdate + Water > ADP + Phosphate + Molybdate + Hydrogen ion Adenosine triphosphate + Molybdate + Water > ADP + Phosphate + Molybdate + Hydrogen ion Adenylated molybdopterin + Molybdate > molybdenum cofactor + Adenosine monophosphate + Water Adenosine triphosphate + Water + Molybdate > ADP + Inorganic phosphate + Molybdate Adenosine triphosphate + Water + Molybdate > ADP + Inorganic phosphate + Molybdate Adenylyl-molybdopterin + Molybdate > Molybdopterin + Adenosine monophosphate Adenylyl-molybdopterin + Hydrogen ion + Molybdate > Adenosine monophosphate + Water + molybdenum cofactor | ||||||||||||||||||||||||||||||||||||||||||||||||
| SMPDB Pathways: |
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| KEGG Pathways: |
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| EcoCyc Pathways: |
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| Concentrations | |||||||||||||||||||||||||||||||||||||||||||||||||
| Not Available | |||||||||||||||||||||||||||||||||||||||||||||||||
| Spectra | |||||||||||||||||||||||||||||||||||||||||||||||||
| Spectra: | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| References | |||||||||||||||||||||||||||||||||||||||||||||||||
| References: |
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| Synthesis Reference: | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| Material Safety Data Sheet (MSDS) | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
| Links | |||||||||||||||||||||||||||||||||||||||||||||||||
| External Links: |
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Enzymes
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
- Gene Name:
- cysA
- Uniprot ID:
- P16676
- Molecular weight:
- 41059
Reactions
| ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In). |
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- cysW
- Uniprot ID:
- P0AEB0
- Molecular weight:
- 32537
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- modB
- Uniprot ID:
- P0AF01
- Molecular weight:
- 24939
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- cysU
- Uniprot ID:
- P16701
- Molecular weight:
- 30292
- General function:
- Involved in transporter activity
- Specific function:
- This protein specifically binds sulfate and is involved in its transmembrane transport
- Gene Name:
- sbp
- Uniprot ID:
- P0AG78
- Molecular weight:
- 36659
- General function:
- Involved in Mo-molybdopterin cofactor biosynthetic process
- Specific function:
- Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP
- Gene Name:
- moeA
- Uniprot ID:
- P12281
- Molecular weight:
- 44067
Reactions
| Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP. |
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
- Gene Name:
- cysP
- Uniprot ID:
- P16700
- Molecular weight:
- 37614
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
- Gene Name:
- modC
- Uniprot ID:
- P09833
- Molecular weight:
- 39102
Reactions
| ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In). |
- General function:
- Involved in molybdate transmembrane-transporting ATPase activity
- Specific function:
- Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity
- Gene Name:
- modA
- Uniprot ID:
- P37329
- Molecular weight:
- 27364
Transporters
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
- Gene Name:
- cysA
- Uniprot ID:
- P16676
- Molecular weight:
- 41059
Reactions
| ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In). |
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- cysW
- Uniprot ID:
- P0AEB0
- Molecular weight:
- 32537
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- modB
- Uniprot ID:
- P0AF01
- Molecular weight:
- 24939
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- cysU
- Uniprot ID:
- P16701
- Molecular weight:
- 30292
- General function:
- Involved in transporter activity
- Specific function:
- This protein specifically binds sulfate and is involved in its transmembrane transport
- Gene Name:
- sbp
- Uniprot ID:
- P0AG78
- Molecular weight:
- 36659
- General function:
- Involved in transporter activity
- Specific function:
- Non-specific porin
- Gene Name:
- ompN
- Uniprot ID:
- P77747
- Molecular weight:
- 41220
- General function:
- Involved in transporter activity
- Specific function:
- Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
- Gene Name:
- cysP
- Uniprot ID:
- P16700
- Molecular weight:
- 37614
- General function:
- Involved in transporter activity
- Specific function:
- Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
- Gene Name:
- phoE
- Uniprot ID:
- P02932
- Molecular weight:
- 38922
- General function:
- Involved in transporter activity
- Specific function:
- OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
- Gene Name:
- ompF
- Uniprot ID:
- P02931
- Molecular weight:
- 39333
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
- Gene Name:
- modC
- Uniprot ID:
- P09833
- Molecular weight:
- 39102
Reactions
| ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In). |
- General function:
- Involved in transporter activity
- Specific function:
- Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
- Gene Name:
- ompC
- Uniprot ID:
- P06996
- Molecular weight:
- 40368
- General function:
- Involved in molybdate transmembrane-transporting ATPase activity
- Specific function:
- Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity
- Gene Name:
- modA
- Uniprot ID:
- P37329
- Molecular weight:
- 27364