2.0 2012-05-31 14:37:05 -0600 2015-06-03 17:19:42 -0600 ECMDB20282 M2MDB001122 L-Ribose Ribose is an organic compound that occurs widely in nature. It is an aldopentose, a monosaccharide containing five carbon atoms that in its acyclic form has an aldehyde functional group at one end. Typically, ribose exists in the cyclic form. It comprises the backbone of RNA, a biopolymer that is the basis of genetic transcription. It is related to deoxyribose, as found in DNA, by the removal of one hydroxy group. Once phosphorylated, ribose can become a subunit of ATP, NADH, and several other compounds that are critical to metabolism. Ribose exists in two enantiomeric forms, primarily as D-ribose. L-ribose is the synthetic mirror image of D-ribose. (Wikipedia) In E. coli, L-ribose can act as an competitive inhibitor of glucose dehydrogenase. (EcoCyc) (2S,3S,4S)-2,3,4,5-tetrahydroxypentanal Aldehydo-L-ribo-pentose Aldehydo-L-ribose Arabinose C5H10O5 150.1299 150.05282343 (2S,3S,4S)-2,3,4,5-tetrahydroxypentanal L-ribose 24259-59-4 [H][C@](O)(CO)[C@]([H])(O)[C@]([H])(O)C=O InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m1/s1 PYMYPHUHKUWMLA-MROZADKFSA-N Solid Cytoplasm Periplasm logp -2.28 ALOGPS logs 0.40 ALOGPS solubility 3.80e+02 g/l ALOGPS melting_point 99 °C, 372 K, 210 °F logp -2.9 ChemAxon pka_strongest_acidic 11.87 ChemAxon pka_strongest_basic -3 ChemAxon iupac (2S,3S,4S)-2,3,4,5-tetrahydroxypentanal ChemAxon average_mass 150.1299 ChemAxon mono_mass 150.05282343 ChemAxon smiles [H][C@](O)(CO)[C@]([H])(O)[C@]([H])(O)C=O ChemAxon formula C5H10O5 ChemAxon inchi InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m1/s1 ChemAxon inchikey PYMYPHUHKUWMLA-MROZADKFSA-N ChemAxon polar_surface_area 97.99 ChemAxon refractivity 31.38 ChemAxon polarizability 13.38 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 5 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 1085261 Specdb::NmrOneD 326222 Specdb::NmrOneD 326223 Specdb::NmrOneD 326224 Specdb::NmrOneD 326225 Specdb::NmrOneD 326226 Specdb::NmrOneD 326227 Specdb::NmrOneD 326228 Specdb::NmrOneD 326229 Specdb::NmrOneD 326230 Specdb::NmrOneD 326231 Specdb::NmrOneD 326232 Specdb::NmrOneD 326233 Specdb::NmrOneD 326234 Specdb::NmrOneD 326235 Specdb::NmrOneD 326236 Specdb::NmrOneD 326237 Specdb::NmrOneD 326238 Specdb::NmrOneD 326239 Specdb::NmrOneD 326240 Specdb::NmrOneD 326241 Specdb::MsMs 26561 Specdb::MsMs 26562 Specdb::MsMs 26563 Specdb::MsMs 33119 Specdb::MsMs 33120 Specdb::MsMs 33121 90428 81643 46997 CPD-6001 Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. 21097882 Ribose transport system permease protein rbsC P0AGI1 RBSC_ECOLI rbsC http://ecmdb.ca/proteins/P0AGI1.xml Sugar efflux transporter C P31436 SETC_ECOLI setC http://ecmdb.ca/proteins/P31436.xml Ribose transport system permease protein rbsC P0AGI1 RBSC_ECOLI rbsC http://ecmdb.ca/proteins/P0AGI1.xml