Record Information |
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Version | 2.0 |
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Creation Date | 2012-05-31 14:03:00 -0600 |
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Update Date | 2015-09-13 12:56:13 -0600 |
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Secondary Accession Numbers | |
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Identification |
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Name: | Chloride |
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Description | The chloride ion is formed when the element chlorine picks up one electron to form an anion (negatively-charged ion) Cl. Chloride is an important anion in all living systems (being part of NaCl and KCl) and cells actively transport chloride ions to help maintain an appropriate ion balance. |
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Structure | |
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Synonyms: | - Bertholite
- Chloor
- Chlor
- Chlore
- Chloride
- Chloride ion
- Chlorine
- Chlorine gas
- Cl
- Cl-
- Cl2
- Cl-
- Diatomic chlorine
- Dichlorine
- Molecular chlorine
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Chemical Formula: | Cl |
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Weight: | Average: 35.453 Monoisotopic: 34.968852707 |
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InChI Key: | VEXZGXHMUGYJMC-UHFFFAOYSA-M |
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InChI: | InChI=1S/ClH/h1H/p-1 |
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CAS number: | 16887-00-6 |
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IUPAC Name: | chloride |
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Traditional IUPAC Name: | chloride |
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SMILES: | [Cl-] |
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Chemical Taxonomy |
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Description | belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas. |
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Kingdom | Inorganic compounds |
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Super Class | Homogeneous non-metal compounds |
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Class | Homogeneous halogens |
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Sub Class | Not Available |
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Direct Parent | Homogeneous halogens |
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Alternative Parents | Not Available |
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Substituents | |
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Molecular Framework | Not Available |
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External Descriptors | |
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Physical Properties |
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State: | Gas |
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Charge: | -1 |
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Melting point: | -101 °C |
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Experimental Properties: | Property | Value | Source |
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Water Solubility: | 6.3 mg/mL at 25 oC [AMOORE,JE & HAUTALA,E (1983)] | PhysProp |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations: | Cytoplasm |
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Reactions: | |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | - Aldosterone-regulated sodium reabsorption ec04960
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EcoCyc Pathways: | Not Available |
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Concentrations |
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| Concentration | Strain | Media | Growth Status | Growth System | Temperature | Details |
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44500± 2000 uM | K12 | 16 mM NaH2PO4; 32 mM Na2HPO4; 5 mM (NH4)2SO4; 40 mM NaCl; 5 mM KCl; 0.4 mM MgSO4, 55 mM glucose | Stationary Phase (50 mM chloride in media) | Shake flask | 37 oC | PMID: 13909522 | 17100± 900 uM | K12 | 16 mM NaH2PO4; 32 mM Na2HPO4; 5 mM (NH4)2SO4; 40 mM NaCl; 5 mM KCl; 0.4 mM MgSO4, 55 mM glucose | Mid-Log Phase (50 mM chloride in media) | Shake flask | 37 oC | PMID: 13909522 | 6000± 0 uM | K-12 | Not Available | Not Available | Not Available | Not Available | 1. Cybercell Database: http://ccdb.wishartlab.com/CCDB/cgi-bin/STAT_NEW.cgi
2. Phillips R., Kondev, J., Theriot, J. (2008) “Physical Biology of the Cell” Garland Science, New York, NY. |
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Spectra |
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Spectra: | Spectrum Type | Description | Splash Key | |
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LC-MS/MS | LC-MS/MS Spectrum - 40V, Positive | splash10-00di-0009000000-6fb9c471131023c432df | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - 30V, Positive | splash10-00di-0009000000-81a678b03172c0d73abf | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - 10V, Positive | splash10-00di-0009000000-5df8560ed945712b8481 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - 20V, Positive | splash10-00di-0009000000-80bd16051562ea5ee2b7 | View in MoNA |
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LC-MS/MS | LC-MS/MS Spectrum - 50V, Positive | splash10-0a4i-0009000000-cf0884f0a8324da15f74 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-000i-9000000000-c4fb3d037fe2e74c2a5e | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-000i-9000000000-c4fb3d037fe2e74c2a5e | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-000i-9000000000-c4fb3d037fe2e74c2a5e | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-9000000000-d488e6da5c7ecb77869a | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-001i-9000000000-d488e6da5c7ecb77869a | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-001i-9000000000-d488e6da5c7ecb77869a | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-9000000000-c2fa753da65a4bac80a1 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-001i-9000000000-c2fa753da65a4bac80a1 | View in MoNA |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-001i-9000000000-c2fa753da65a4bac80a1 | View in MoNA |
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References |
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References: | - Evans RB: Chlorine: state of the art. Lung. 2005 May-Jun;183(3):151-67. Pubmed: 16078037
- Fainsinger RL: Palliative care in Edmonton. Support Care Cancer. 1995 Mar;3(2):91-2. Pubmed: 7539703
- Harrison NL: Mechanisms of sleep induction by GABA(A) receptor agonists. J Clin Psychiatry. 2007;68 Suppl 5:6-12. Pubmed: 17539703
- Kahle KT, Wilson FH, Lalioti M, Toka H, Qin H, Lifton RP: WNK kinases: molecular regulators of integrated epithelial ion transport. Curr Opin Nephrol Hypertens. 2004 Sep;13(5):557-62. Pubmed: 15300163
- Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. Pubmed: 22080510
- Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
- SCHULTZ, S. G., WILSON, N. L., EPSTEIN, W. (1962). "Cation transport in Escherichia coli. II. Intracellular chloride concentration." J Gen Physiol 46:159-166. Pubmed: 13909522
- Tarran R, Donaldson S, Boucher RC: Rationale for hypertonic saline therapy for cystic fibrosis lung disease. Semin Respir Crit Care Med. 2007 Jun;28(3):295-302. Pubmed: 17562499
- Zifarelli G, Pusch M: CLC chloride channels and transporters: a biophysical and physiological perspective. Rev Physiol Biochem Pharmacol. 2007;158:23-76. Pubmed: 17729441
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Synthesis Reference: | Weber, Rainer; Bulan, Andreas; Haas, Michel; Warsitz, Rafael; Werner, Knud. Production of chlorine from hydrogen chloride and oxygen. PCT Int. Appl. (2007), 30pp. CODEN: PIXXD2 WO 2007134861 A1 20071129 CAN 148:35931 AN 2007:1361621 |
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Material Safety Data Sheet (MSDS) | Download (PDF) |
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Links |
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External Links: | |
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