2.02012-05-31 14:02:03 -06002015-06-03 15:54:37 -0600ECMDB04011M2MDB000556Galactose 1-phosphateGalactose 1-phosphate is an intermediate in the Galactose metabolism α-D-Gal-1-Pα-D-galactopyranose 1-phosphateα-D-galactopyranose 1-phosphoric acid1-(Dihydrogen phosphate) Galactitol1-(Dihydrogen phosphoric acid) galactitol1-phosphate a-D-Galactopyranose1-Phosphate alpha-D-Galactopyranose1-Phosphate α-D-galactopyranose1-Phosphoric acid a-D-galactopyranose1-Phosphoric acid alpha-D-galactopyranose1-Phosphoric acid α-D-galactopyranoseA-D-1-(Dihydrogen phosphate) Galactopyranosea-D-1-(Dihydrogen phosphoric acid) galactopyranosea-D-Gal-1-Pa-D-Galactopyranose 1-phosphatea-D-Galactopyranose 1-phosphoric acidA-D-Galactopyranosyl phosphatea-D-Galactopyranosyl phosphoric acidA-D-Galactose 1-phosphatea-D-Galactose 1-phosphoric acidA-D-Galactosyl phosphatea-D-Galactosyl phosphoric acidAlpha-D-1-(Dihydrogen phosphate) Galactopyranosealpha-D-1-(Dihydrogen phosphoric acid) galactopyranoseAlpha-D-Gal-1-PAlpha-D-Galactopyranose 1-phosphatealpha-D-Galactopyranose 1-phosphoric acidAlpha-D-Galactopyranosyl phosphatealpha-D-Galactopyranosyl phosphoric acidAlpha-D-Galactose 1-phosphatealpha-D-Galactose 1-phosphoric acidAlpha-D-Galactosyl phosphatealpha-D-Galactosyl phosphoric acidD-Galactose 1-phosphateD-Galactose 1-phosphoric acidD-Galactose-1-phosphateD-Galactose-1-phosphoric acidGalactopyranose 1-phosphateGalactopyranose 1-phosphoric acidGalactose 1-phosphateGalactose 1-phosphoric acidGalactose-1-Pα-D-1-(Dihydrogen phosphate) galactopyranoseα-D-1-(Dihydrogen phosphoric acid) galactopyranoseα-D-Gal-1-Pα-D-Galactopyranose 1-phosphateα-D-Galactopyranose 1-phosphoric acidα-D-Galactopyranosyl phosphateα-D-Galactopyranosyl phosphoric acidα-D-Galactose 1-phosphateα-D-Galactose 1-phosphoric acidα-D-Galactosyl phosphateα-D-Galactosyl phosphoric acidC6H13O9P260.1358260.029718526{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acidgalactose 1 phosphate2255-14-3OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1OInChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3+,4+,5-,6-/m1/s1HXXFSFRBOHSIMQ-FPRJBGLDSA-NSolidCytosolExtra-organismPeriplasmlogp-2.00logs-0.91solubility3.23e+01 g/llogp-3.1pka_strongest_acidic1.16pka_strongest_basic-3iupac{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acidaverage_mass260.1358mono_mass260.029718526smilesOC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1OformulaC6H13O9PinchiInChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3+,4+,5-,6-/m1/s1inchikeyHXXFSFRBOHSIMQ-FPRJBGLDSA-Npolar_surface_area156.91refractivity46.8polarizability20.62rotatable_bond_count3acceptor_count8donor_count6physiological_charge-2formal_charge0Starch and sucrose metabolismThe metabolism of starch and sucrose begins with D-fructose interacting with a D-glucose in a reversible reaction through a maltodextrin glucosidase resulting in a water molecule and a sucrose. D-fructose is phosphorylated through an ATP driven fructokinase resulting in the release of an ADP, a hydrogen ion and a Beta-D-fructofuranose 6-phosphate. This compound can also be introduced into the cytoplasm through either a mannose PTS permease or a hexose-6-phosphate:phosphate antiporter.
The Beta-D-fructofuranose 6-phosphate is isomerized through a phosphoglucose isomerase resulting in a Beta-D-glucose 6-phosphate. This compound can also be incorporated by glucose PTS permease or a hexose-6-phosphate:phosphate antiporter.
The beta-D-glucose 6 phosphate can also be produced by a D-glucose being phosphorylated by an ATP-driven glucokinase resulting in a ADP, a hydrogen ion and a Beta-D-glucose 6 phosphate.
The beta-D-glucose can produce alpha-D-glucose-1-phosphate by two methods:
1.-Beta-D-glucose is isomerized into an alpha-D-Glucose 6-phosphate and then interacts in a reversible reaction through a phosphoglucomutase-1 resulting in a alpha-D-glucose-1-phosphate.
2.-Beta-D-glucose interacts with a putative beta-phosphoglucomutase resulting in a Beta-D-glucose 1-phosphate. Beta-D-glucose 1-phosphate can be incorporated into the cytoplasm through a
glucose PTS permease. This compound is then isomerized into a Alpha-D-glucose-1-phosphate
The beta-D-glucose can cycle back into a D-fructose by first interacting with D-fructose in a reversible reaction through a Polypeptide: predicted glucosyltransferase resulting in the release of a phosphate and a sucrose. The sucrose then interacts in a reversible reaction with a water molecule through a maltodextrin glucosidase resulting in a D-glucose and a D-fructose.
Alpha-D-glucose-1-phosphate can produce glycogen in by two different sets of reactions:
1.-Alpha-D-glucose-1-phosphate interacts with a hydrogen ion and an ATP through a glucose-1-phosphate adenylyltransferase resulting in a pyrophosphate and an ADP-glucose. The ADP-glucose then interacts with an amylose through a glycogen synthase resulting in the release of an ADP and an Amylose. The amylose then interacts with 1,4-α-glucan branching enzyme resulting in glycogen
2.- Alpha-D-glucose-1-phosphate interacts with amylose through a maltodextrin phosphorylase resulting in a phosphate and a glycogen.
Alpha-D-glucose-1-phosphate can also interacts with UDP-galactose through a galactose-1-phosphate uridylyltransferase resulting in a galactose 1-phosphate and a Uridine diphosphate glucose. The UDP-glucose then interacts with an alpha-D-glucose 6-phosphate through a trehalose-6-phosphate synthase resulting in a uridine 5'-diphosphate, a hydrogen ion and a Trehalose 6- phosphate. The latter compound can also be incorporated into the cytoplasm through a trehalose PTS permease. Trehalose interacts with a water molecule through a trehalose-6-phosphate phosphatase resulting in the release of a phosphate and an alpha,alpha-trehalose.The alpha,alpha-trehalose can also be obtained from glycogen being metabolized through a glycogen debranching enzyme resulting in a the alpha, alpha-trehalose. This compound ca then be hydrated through a cytoplasmic trehalase resulting in the release of an alpha-D-glucose and a beta-d-glucose.
Glycogen is then metabolized by reacting with a phosphate through a glycogen phosphorylase resulting in a alpha-D-glucose-1-phosphate and a dextrin. The dextrin is then hydrated through a glycogen phosphorylase-limit dextrin α-1,6-glucohydrolase resulting in the release of a debranched limit dextrin and a maltotetraose. This compound can also be incorporated into the cytoplasm through a
maltose ABC transporter. The maltotetraose interacts with a phosphate through a maltodextrin phosphorylase releasing a alpha-D-glucose-1-phosphate and a maltotriose. The maltotriose can also be incorporated through a maltose ABC transporter. The maltotriose can then interact with water through a maltodextrin glucosidase resulting in a D-glucose and a D-maltose. D-maltose can also be incorporated through a
maltose ABC transporter
The D-maltose can then interact with a maltotriose through a amylomaltase resulting in a maltotetraose and a D-glucose. The D-glucose is then phosphorylated through an ATP driven glucokinase resulting in a hydrogen ion, an ADP and a Beta-D-glucose 6-phosphatePW000941ec00500MetabolicGalactose metabolismGalactose can be synthesized through two pathways: melibiose degradation involving an alpha galactosidase and lactose degradation involving a beta galactosidase. Melibiose is first transported inside the cell through the melibiose:Li+/Na+/H+ symporter. Once inside the cell, melibiose is degraded through alpha galactosidase into an alpha-D-galactose and a beta-D-glucose. The beta-D-glucose is phosphorylated by a glucokinase to produce a beta-D-glucose-6-phosphate which can spontaneously be turned into a alpha D glucose 6 phosphate. This alpha D-glucose-6-phosphate is metabolized into a glucose -1-phosphate through a phosphoglucomutase-1. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase.
Galactose can also be produced by lactose degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase to turn lactose into Beta-D-galactose.
Beta-D-galactose can also be uptaken from the environment through a galactose proton symporter.
Galactose is degraded through the following process:
Beta-D-galactose is introduced into the cytoplasm through a galactose proton symporter, or it can be synthesized from an alpha lactose that is introduced into the cytoplasm through a lactose permease. Alpha lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D-galactose. Beta-D-galactose is isomerized into D-galactose. D-Galactose undergoes phosphorylation through a galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1-phosphate (product of the interaction of alpha-D-glucose 6-phosphate with a phosphoglucomutase resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate glucose. This is followed by the interaction of galactose-1-phosphate with an established amount of uridine diphosphate glucose through a galactose-1-phosphate uridylyltransferase, which in turn output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase, and so the cycle can keep going as long as more lactose or galactose is imported into the cell
PW000821ec00052MetabolicAmino sugar and nucleotide sugar metabolismec00520Metabolic pathwayseco01100Amino sugar and nucleotide sugar metabolism IIThe synthesis of amino sugars and nucleotide sugars starts with the phosphorylation of N-Acetylmuramic acid (MurNac) through its transport from the periplasmic space to the cytoplasm. Once in the cytoplasm, MurNac and water undergo a reversible reaction through a N-acetylmuramic acid 6-phosphate etherase, producing a D-lactic acid and N-Acetyl-D-Glucosamine 6-phosphate. This latter compound can also be introduced into the cytoplasm through a phosphorylating PTS permase in the inner membrane that allows for the transport of N-Acetyl-D-glucosamine from the periplasmic space. N-Acetyl-D-Glucosamine 6-phosphate can also be obtained from chitin dependent reactions. Chitin is hydrated through a bifunctional chitinase to produce chitobiose. This in turn gets hydrated by a beta-hexosaminidase to produce N-acetyl-D-glucosamine. The latter undergoes an atp dependent phosphorylation leading to the production of N-Acetyl-D-Glucosamine 6-phosphate.
N-Acetyl-D-Glucosamine 6-phosphate is then be deacetylated in order to produce Glucosamine 6-phosphate through a N-acetylglucosamine-6-phosphate deacetylase. This compound is then deaminased into Beta-D-fructofuranose 6-phosphate through a glucosamine-6-phosphate deaminase.
The beta-D-fructofuranose 6 -phosphate is isomerized in a reversible reaction into an alpha-D-mannose 6-phosphate. This compound can also be introduced into the cell from the periplasmic space through a mannose PTS permease that phosphorylates an alpha-D-mannose. Alpha-D-mannose 6-phosphate undergoes a reversible reaction through a phosphomannomutase to produce an alpha-D-mannose 1-phosphate.
The alpha-D-mannose 1-phosphate enters the nucleotide sugar metabolism through a reaction with GTP producing a GDP-mannose and releasing a pyrophosphate, all through a mannose-1-phosphate guanylyltransferase. GDP-mannose is then dehydrated to produce GDP-4-dehydro-6-deoxy-alpha-D-mannose through a GDP-mannose 4,6-dehydratase. This compound is then used to synthesize GDP-Beta-L-fucose through a NADPH dependent GDP-L-fucose synthase.
Alpha-D-glucose is introduced into the cytoplasm through a glucose PTS permease, which phosphorylates the compound in order to produce an alpha-D-glucose 6-phosphate. This compound is then modified through a phosphoglucomutase 1 to yield alpha-D-glucose 1-phosphate. This compound can either be adenylated to produce ADP-glucose or uridylylated to produce galactose 1-phosphate through glucose-1-phosphate adenyllyltransferase and galactose-1-phosphate uridylyltransferase respectively.PW000887MetabolicAmino sugar and nucleotide sugar metabolism IIIThe synthesis of amino sugars and nucleotide sugars starts with the phosphorylation of N-Acetylmuramic acid (MurNac) through its transport from the periplasmic space to the cytoplasm. Once in the cytoplasm, MurNac and water undergo a reversible reaction through a N-acetylmuramic acid 6-phosphate etherase, producing a D-lactic acid and N-Acetyl-D-Glucosamine 6-phosphate. This latter compound can also be introduced into the cytoplasm through a phosphorylating PTS permase in the inner membrane that allows for the transport of N-Acetyl-D-glucosamine from the periplasmic space. N-Acetyl-D-Glucosamine 6-phosphate can also be obtained from chitin dependent reactions. Chitin is hydrated through a bifunctional chitinase to produce chitobiose. This in turn gets hydrated by a beta-hexosaminidase to produce N-acetyl-D-glucosamine. The latter undergoes an atp dependent phosphorylation leading to the production of N-Acetyl-D-Glucosamine 6-phosphate.
N-Acetyl-D-Glucosamine 6-phosphate is then be deacetylated in order to produce Glucosamine 6-phosphate through a N-acetylglucosamine-6-phosphate deacetylase. This compound is then deaminased into Beta-D-fructofuranose 6-phosphate through a glucosamine-6-phosphate deaminase.
Beta-D-fructofuranose 6-phosphate is isomerized into a beta-D-glucose 6-phosphate through a glucose-6-phosphate isomerase. The compound is then isomerized by a putative beta-phosphoglucomutase to produce a beta-D-glucose 1-phosphate. This compound enters the nucleotide sugar metabolism through uridylation resulting in a UDP-glucose. UDP-glucose is then dehydrated through a UDP-glucose 6-dehydrogenase to produce a UDP-glucuronic acid. This compound undergoes a NAD dependent reaction through a bifunctional polymyxin resistance protein to produce UDP-Beta-L-threo-pentapyranos-4-ulose. This compound then reacts with L-glutamic acid through a UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase to produce an oxoglutaric acid and UDP-4-amino-4-deoxy-beta-L-arabinopyranose
The latter compound interacts with a N10-formyl-tetrahydrofolate through a bifunctional polymyxin resistance protein ArnA, resulting in a tetrahydrofolate, a hydrogen ion and a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose, which in turn reacts with a product of the methylerythritol phosphate and polysoprenoid biosynthesis pathway, di-trans,octa-cis-undecaprenyl phosphate to produce a 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate.
Alpha-D-glucose is introduced into the cytoplasm through a glucose PTS permease, which phosphorylates the compound in order to produce an alpha-D-glucose 6-phosphate. This compound is then modified through a phosphoglucomutase 1 to yield alpha-D-glucose 1-phosphate. This compound can either be adenylated to produce ADP-glucose or uridylylated to produce galactose 1-phosphate through glucose-1-phosphate adenyllyltransferase and galactose-1-phosphate uridylyltransferase respectively.PW000895MetabolicGalactitol and galactonate degradationD-galactonate can serve as the sole source of carbon and energy for E. coli . The initial step, after the transport of galactonic acid into the cell is the degradation of D-galactonate is dehydration to 2-dehydro-3-deoxy-D-galactonate by D-galactonate dehydratase. Subsequent phosphorylation by 2-dehydro-3-deoxygalactonate kinase and aldol cleavage by 2-oxo-3-deoxygalactonate 6-phosphate aldolase produce pyruvate and D-glyceraldehyde-3-phosphate, which enter central metabolism.
Galactitol can also be utilized by E. coli K-12 as a total source of carbon and energy. Each enters the cell via a specific phosphotransferase system, so the first intracellular species is D-galactitol-1-phosphate or D-galactitol-6-phosphate, which are identical. This sugar alcohol phosphate becomes the substrate for a dehydrogenase that oxidizes its 2-alcohol group to a keto group. Galactitol-1-phosphate, the product of the dehydrogenation is tagatose-6-phosphate, which becomes the substrate of a kinase and subsequently an aldolase (in a pair of reactions that parallel those of glycolysis) before it is converted into intermediates (D-glyceraldehde-3-phosphate and dihydroxy-acetone-phosphate) of glycolysis.PW000820Metabolicgalactose degradation/Leloir PathwayThe degradation of galactose, also known as Leloir pathway, requires 3 main enzymes once Beta-D-galactose has been converted to galactose through an Aldose-1-epimerase. These are: galactokinase , galactose-1-phosphate uridylyltransferase and UDP-glucose 4-epimerase. Beta-D-galactose can be uptaken from the environment through a galactose proton symporter. It can also be produced by lactose degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase to turn lactose into Beta-D-galactose.
Galactose is degraded through the following process:
Beta-D-galactose is introduced into the cytoplasm through a galactose proton symporter, or it can be synthesized from an alpha lactose that is introduced into the cytoplasm through a lactose permease. Alpha lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D-galactose. Beta-D-galactose is isomerized into D-galactose. D-Galactose undergoes phosphorylation through a galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1-phosphate (product of the interaction of alpha-D-glucose 6-phosphate with a phosphoglucomutase resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate glucose. This is followed by the interaction of galactose-1-phosphate with an established amount of uridine diphosphate glucose through a galactose-1-phosphate uridylyltransferase, which in turn output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase, and so the cycle can keep going as long as more lactose or galactose is imported into the cell.
PW000884Metabolicgalactose degradation I (Leloir pathway)GALACTMETAB-PWYcolanic acid building blocks biosynthesisCOLANSYN-PWYSpecdb::CMs2915Specdb::CMs37670Specdb::CMs134920Specdb::CMs142654Specdb::CMs1071142Specdb::CMs1071144Specdb::CMs1071146Specdb::CMs1071148Specdb::CMs1071150Specdb::CMs1071151Specdb::CMs1071153Specdb::CMs1071155Specdb::CMs1071157Specdb::CMs1071159Specdb::CMs1071161Specdb::CMs1071163Specdb::CMs1071165Specdb::CMs1071167Specdb::CMs1071168Specdb::CMs1071170Specdb::CMs1071172Specdb::CMs1071174Specdb::CMs1071176Specdb::CMs1071178Specdb::CMs1071180Specdb::NmrOneD4716Specdb::NmrOneD4717Specdb::NmrOneD144650Specdb::NmrOneD144651Specdb::NmrOneD144652Specdb::NmrOneD144653Specdb::NmrOneD144654Specdb::NmrOneD144655Specdb::NmrOneD144656Specdb::NmrOneD144657Specdb::NmrOneD144658Specdb::NmrOneD144659Specdb::NmrOneD144660Specdb::NmrOneD144661Specdb::NmrOneD144662Specdb::NmrOneD144663Specdb::NmrOneD144664Specdb::NmrOneD144665Specdb::NmrOneD144666Specdb::NmrOneD144667Specdb::NmrOneD144668Specdb::NmrOneD144669Specdb::MsMs28337Specdb::MsMs28338Specdb::MsMs28339Specdb::MsMs34895Specdb::MsMs34896Specdb::MsMs34897Specdb::MsMs439124Specdb::MsMs439278Specdb::MsMs440089Specdb::MsMs1473413Specdb::MsMs1473414Specdb::MsMs1475346Specdb::MsMs1475347Specdb::MsMs1475348Specdb::MsMs1475349Specdb::MsMs1475350Specdb::MsMs1475351Specdb::MsMs1475352Specdb::MsMs1475353Specdb::MsMs1475354Specdb::MsMs1475355Specdb::MsMs1475356Specdb::MsMs1475357Specdb::MsMs1475358Specdb::MsMs1475359HMDB00645439995110443C00446GALACTOSE-1PGL1Galactose 1-phosphateKeseler, I. 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Protein ushAP07024USHA_ECOLIushAhttp://ecmdb.ca/proteins/P07024.xmlGalactose-1-phosphate uridylyltransferaseP09148GAL7_ECOLIgalThttp://ecmdb.ca/proteins/P09148.xmlGalactokinaseP0A6T3GAL1_ECOLIgalKhttp://ecmdb.ca/proteins/P0A6T3.xmlGalactitol-1-phosphate 5-dehydrogenaseP0A9S3GATD_ECOLIgatDhttp://ecmdb.ca/proteins/P0A9S3.xmlGlucose-1-phosphataseP19926AGP_ECOLIagphttp://ecmdb.ca/proteins/P19926.xmlGalactitol-specific phosphotransferase enzyme IIB componentP37188PTKB_ECOLIgatBhttp://ecmdb.ca/proteins/P37188.xmlGalactitol-specific phosphotransferase enzyme IIA componentP69828PTKA_ECOLIgatAhttp://ecmdb.ca/proteins/P69828.xmlGalactitol permease IIC componentP69831PTKC_ECOLIgatChttp://ecmdb.ca/proteins/P69831.xmlColanic acid biosynthesis protein wcaKP71242WCAK_ECOLIwcaKhttp://ecmdb.ca/proteins/P71242.xmlGalactitol permease IIC componentP69831PTKC_ECOLIgatChttp://ecmdb.ca/proteins/P69831.xmlOuter membrane protein NP77747OMPN_ECOLIompNhttp://ecmdb.ca/proteins/P77747.xmlOuter membrane pore protein EP02932PHOE_ECOLIphoEhttp://ecmdb.ca/proteins/P02932.xmlOuter membrane protein FP02931OMPF_ECOLIompFhttp://ecmdb.ca/proteins/P02931.xmlOuter membrane protein CP06996OMPC_ECOLIompChttp://ecmdb.ca/proteins/P06996.xmlAdenosine triphosphate + D-Galactose + Alpha-D-Galactose <> ADP + Galactose 1-phosphate + Hydrogen ionR01092GALACTOKIN-RXNWater + Uridine diphosphategalactose > Galactose 1-phosphate +2 Hydrogen ion + Uridine 5'-monophosphateGalactose 1-phosphate + UDP-Glucose <> Glucose 1-phosphate + Uridine diphosphategalactoseR00955GALACTURIDYLYLTRANS-RXNGalactose 1-phosphate + Water > D-Galactose + PhosphateAdenosine triphosphate + D-Galactose <> ADP + Galactose 1-phosphateR01092D-Galactose + Adenosine triphosphate > Hydrogen ion + Galactose 1-phosphate + ADPR01092GALACTOKIN-RXNAdenosine triphosphate + D-Galactose > ADP + Galactose 1-phosphateUDP-Glucose + Galactose 1-phosphate > Alpha-D-glucose 1-phosphate + Uridine diphosphategalactoseGalactose 1-phosphate + NAD + Galactose 1-phosphate > NADH + Hydrogen ion + D-tagatofuranose 6-phosphatePW_R002943Galactose 1-phosphate + Galactose 1-phosphate > Glucose 1-phosphatePW_R002949Galactose 1-phosphate + UDP-Glucose + Galactose 1-phosphate > Uridine diphosphategalactose + Glucose 1-phosphate + Uridine diphosphategalactosePW_R003296Alpha-D-glucose 1-phosphate + UDP-galactose > UDP-Glucose + Galactose 1-phosphate + Galactose 1-phosphatePW_R003354Alpha-D-Galactose + Adenosine triphosphate > Adenosine diphosphate + Hydrogen ion + Galactose 1-phosphate + ADP + Galactose 1-phosphatePW_R002952Galactitol + HPr - phosphorylated > Galactose 1-phosphate + HPr + Galactose 1-phosphatePW_RCT000113