Propionyl-CoA (ECMDB01275) (M2MDB000321)

General function:

Involved in formate C-acetyltransferase activity

Specific function:

Acetyl-CoA + formate = CoA + pyruvate

Gene Name:

pflB

Uniprot ID:

P09373

Molecular weight:

85357

Reactions

General function:

Involved in phosphate acetyltransferase activity

Specific function:

Acetyl-CoA + phosphate = CoA + acetyl phosphate

Gene Name:

pta

Uniprot ID:

P0A9M8

Molecular weight:

77171

Reactions

General function:

Involved in catalytic activity

Specific function:

Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine

Gene Name:

pflA

Uniprot ID:

P0A9N4

Molecular weight:

28204

Reactions

General function:

Involved in acetyl-CoA C-acyltransferase activity

Specific function:

Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids

Gene Name:

fadA

Uniprot ID:

P21151

Molecular weight:

40876

Reactions

General function:

Involved in acetate-CoA ligase activity

Specific function:

Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis

Gene Name:

acs

Uniprot ID:

P27550

Molecular weight:

72093

Reactions

General function:

Involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

Specific function:

Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity

Gene Name:

prpC

Uniprot ID:

P31660

Molecular weight:

43102

Reactions

General function:

Involved in catalytic activity

Specific function:

Acetyl-CoA + formate = CoA + pyruvate

Gene Name:

pflD

Uniprot ID:

P32674

Molecular weight:

85959

Reactions

General function:

Involved in formate C-acetyltransferase activity

Specific function:

Specific function unknown

Gene Name:

tdcE

Uniprot ID:

P42632

Molecular weight:

85935

Reactions

General function:

Involved in catalytic activity

Specific function:

(S)-methylmalonyl-CoA = propanoyl-CoA + CO(2)

Gene Name:

mmcD

Uniprot ID:

P52045

Molecular weight:

29172

Reactions

General function:

Involved in catalytic activity

Specific function:

Acetyl-CoA + formate = CoA + pyruvate

Gene Name:

ybiW

Uniprot ID:

P75793

Molecular weight:

90125

Reactions

General function:

Involved in transferase activity

Specific function:

Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Strongly involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate and weakly involved in the aerobic degradation of long- chain fatty acids

Gene Name:

fadI

Uniprot ID:

P76503

Molecular weight:

46530

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity

Gene Name:

prpE

Uniprot ID:

P77495

Molecular weight:

69350

Reactions

General function:

Involved in catalytic activity

Specific function:

Specific function unknown

Gene Name:

ygfH

Uniprot ID:

P52043

Molecular weight:

53824

Reactions

General function:

Involved in catalytic activity

Specific function:

Acts as a radical domain for damaged PFL and possibly other radical proteins

Gene Name:

grcA

Uniprot ID:

P68066

Molecular weight:

14284