Uracil (ECMDB00300) (M2MDB000126)

General function:

Involved in transferase activity, transferring glycosyl groups

Specific function:

The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis

Gene Name:

deoA

Uniprot ID:

P07650

Molecular weight:

47207

Reactions

General function:

Involved in nucleoside metabolic process

Specific function:

Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate

Gene Name:

upp

Uniprot ID:

P0A8F0

Molecular weight:

22533

Reactions

General function:

Involved in purine-nucleoside phosphorylase activity

Specific function:

Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules

Gene Name:

deoD

Uniprot ID:

P0ABP8

Molecular weight:

25950

Reactions

General function:

Involved in transferase activity, transferring pentosyl groups

Specific function:

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis

Gene Name:

udp

Uniprot ID:

P12758

Molecular weight:

27159

Reactions

General function:

Involved in hydrolase activity, hydrolyzing N-glycosyl compounds

Specific function:

Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity with decreasing activity in the order uridine, xanthosine, inosine, adenosine, cytidine, guanosine

Gene Name:

rihC

Uniprot ID:

P22564

Molecular weight:

32560

General function:

Involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Specific function:

Cytosine + H(2)O = uracil + NH(3)

Gene Name:

codA

Uniprot ID:

P25524

Molecular weight:

47591

Reactions

General function:

Involved in hydrolase activity, hydrolyzing N-glycosyl compounds

Specific function:

Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine

Gene Name:

rihB

Uniprot ID:

P33022

Molecular weight:

33748

Reactions

General function:

Involved in hydrolase activity, hydrolyzing N-glycosyl compounds

Specific function:

Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively

Gene Name:

rihA

Uniprot ID:

P41409

Molecular weight:

33823

General function:

Involved in FMN binding

Specific function:

Makes part of the rut operon, which is required for the utilization of pyrimidines as sole nitrogen source

Gene Name:

rutF

Uniprot ID:

P75893

Molecular weight:

17749

Reactions

General function:

Involved in iron-sulfur cluster binding

Specific function:

Specific function unknown

Gene Name:

yeiA

Uniprot ID:

P25889

Molecular weight:

45069

Reactions

General function:

Involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Specific function:

Part of the rut operon, which is required for the utilization of pyrimidines as sole nitrogen source

Gene Name:

rutA

Uniprot ID:

P75898

Molecular weight:

42219

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Specific function unknown

Gene Name:

yeiT

Uniprot ID:

P76440

Molecular weight:

44329

Reactions