Glycerol (ECMDB00131) (M2MDB000050)

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Hydrolysis of terminal, non-reducing alpha-D- galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids

Gene Name:

melA

Uniprot ID:

P06720

Molecular weight:

50657

Reactions

General function:

Involved in glycerophosphodiester phosphodiesterase activity

Specific function:

Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols

Gene Name:

glpQ

Uniprot ID:

P09394

Molecular weight:

40843

Reactions

General function:

Involved in phosphotransferase activity, alcohol group as acceptor

Specific function:

Key enzyme in the regulation of glycerol uptake and metabolism

Gene Name:

glpK

Uniprot ID:

P0A6F3

Molecular weight:

56230

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. In E.coli, an important role of gldA is also likely to regulate the intracellular level of dihydroxyacetone by catalyzing the reverse reaction, i.e. the conversion of dihydroxyacetone into glycerol. Possesses a broad substrate specificity, since it is also able to oxidize 1,2-propanediol and to reduce glycolaldehyde, methylglyoxal and hydroxyacetone into ethylene glycol, lactaldehyde and 1,2-propanediol, respectively

Gene Name:

gldA

Uniprot ID:

P0A9S5

Molecular weight:

38712

Reactions

General function:

Involved in phosphatidylinositol phosphorylation

Specific function:

Myo-inositol phosphate + H(2)O = myo-inositol + phosphate

Gene Name:

suhB

Uniprot ID:

P0ADG4

Molecular weight:

29172

Reactions

General function:

Involved in acid phosphatase activity

Specific function:

Dephosphorylates several organic phosphomonoesters and catalyzes the transfer of low-energy phosphate groups from phosphomonoesters to hydroxyl groups of various organic compounds. Preferentially acts on aryl phosphoesters. Might function as a broad-spectrum dephosphorylating enzyme able to scavenge both 3'- and 5'-nucleotides and also additional organic phosphomonoesters

Gene Name:

aphA

Uniprot ID:

P0AE22

Molecular weight:

26103

Reactions

General function:

Involved in glycerophosphodiester phosphodiesterase activity

Specific function:

Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols

Gene Name:

ugpQ

Uniprot ID:

P10908

Molecular weight:

27409

Reactions

General function:

Involved in zinc ion binding

Specific function:

Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent. In addition, hemithiolacetals other than those formed from GSH, including omega-thiol fatty acids, also are substrates

Gene Name:

frmA

Uniprot ID:

P25437

Molecular weight:

39359

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo

Gene Name:

supH

Uniprot ID:

P75792

Molecular weight:

30413

Reactions

General function:

Involved in phosphotransferase activity, for other substituted phosphate groups

Specific function:

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Affects resistance to the gyrase inhibitor novobiocin

Gene Name:

cls

Uniprot ID:

P0A6H8

Molecular weight:

54822

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate. Catalyzes little, if any, cardiolipin synthesis in vivo, even when the expression level is very high

Gene Name:

ybhO

Uniprot ID:

P0AA84

Molecular weight:

47633

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

yfbT

Uniprot ID:

P77625

Molecular weight:

Not Available