Record Information |
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Version | 2.0 |
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Creation Date | 2012-08-09 09:25:18 -0600 |
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Update Date | 2015-06-03 17:21:43 -0600 |
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Secondary Accession Numbers | |
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Identification |
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Name: | Deoxycytidine 5'-triphosphate |
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Description | Deoxycytidine triphosphate (dCTP) is a cytidine nucleotide triphosphate that is used whenever DNA is synthesized by DNA polymerase. During DNA synthesis dCTP has the PPi (pyrophosphate) cleaved off and the dCMP is incorporated into the DNA strand at the 3' end. |
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Structure | |
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Synonyms: | - 2'-Deoxycytidine 5'-(tetrahydrogen triphosphate)
- 2'-Deoxycytidine 5'-(tetrahydrogen triphosphoric acid)
- 2'-Deoxycytidine 5'-triphosphate
- 2'-Deoxycytidine 5'-triphosphoric acid
- 2'-Deoxycytidine-5'-triphosphate
- 2'-Deoxycytidine-5'-triphosphoric acid
- 2-Deoxycytidine 5-triphosphate
- 2-Deoxycytidine 5-triphosphoric acid
- DCTP
- Deoxy-CTP
- Deoxycytidine 5'-triphosphate
- Deoxycytidine 5'-triphosphoric acid
- Deoxycytidine 5-triphosphate
- Deoxycytidine 5-triphosphoric acid
- Deoxycytidine triphosphate
- Deoxycytidine triphosphoric acid
- Deoxycytidine-triphosphate
- Deoxycytidine-triphosphoric acid
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Chemical Formula: | C9H16N3O13P3 |
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Weight: | Average: 467.1569 Monoisotopic: 466.989597149 |
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InChI Key: | RGWHQCVHVJXOKC-GKROBHDKSA-N |
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InChI: | InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8-/m1/s1 |
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CAS number: | 2056-98-6 |
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IUPAC Name: | ({[({[(2S,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid |
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Traditional IUPAC Name: | ({[(2S,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid |
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SMILES: | NC1=NC(=O)N(C=C1)[C@H]1C[C@@H](O)[C@H](CO[P@@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)O1 |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleoside triphosphates. These are pyrimidine nucleotides with a triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. |
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Kingdom | Organic compounds |
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Super Class | Nucleosides, nucleotides, and analogues |
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Class | Pyrimidine nucleotides |
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Sub Class | Pyrimidine deoxyribonucleotides |
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Direct Parent | Pyrimidine 2'-deoxyribonucleoside triphosphates |
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Alternative Parents | |
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Substituents | - Pyrimidine 2'-deoxyribonucleoside triphosphate
- Aminopyrimidine
- Pyrimidone
- Monoalkyl phosphate
- Hydropyrimidine
- Organic phosphoric acid derivative
- Phosphoric acid ester
- Pyrimidine
- Imidolactam
- Alkyl phosphate
- Heteroaromatic compound
- Tetrahydrofuran
- Secondary alcohol
- Oxacycle
- Azacycle
- Organoheterocyclic compound
- Hydrocarbon derivative
- Primary amine
- Organic oxide
- Organooxygen compound
- Organonitrogen compound
- Organopnictogen compound
- Organic oxygen compound
- Alcohol
- Amine
- Organic nitrogen compound
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | Not Available |
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Physical Properties |
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State: | Solid |
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Charge: | -3 |
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Melting point: | Not Available |
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Experimental Properties: | |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations: | Cytoplasm |
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Reactions: | |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | Not Available |
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EcoCyc Pathways: | Not Available |
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Concentrations |
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| Not Available |
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Spectra |
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Spectra: | |
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References |
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References: | - Winder, C. L., Dunn, W. B., Schuler, S., Broadhurst, D., Jarvis, R., Stephens, G. M., Goodacre, R. (2008). "Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites." Anal Chem 80:2939-2948. Pubmed: 18331064
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Synthesis Reference: | Not Available |
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Material Safety Data Sheet (MSDS) | Not Available |
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Links |
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External Links: | Resource | Link |
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CHEBI ID | 16311 | HMDB ID | HMDB00998 | Pubchem Compound ID | 625 | Kegg ID | C00458 | ChemSpider ID | Not Available | Wikipedia | dCTP | BioCyc ID | Not Available |
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