Inorganic phosphate (ECMDB21380) (M2MDB001776)
Enzymes
- General function:
- Involved in phosphorylase activity
- Specific function:
- Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
- Gene Name:
- malP
- Uniprot ID:
- P00490
- Molecular weight:
- 90522
Reactions
(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- A phosphate monoester + H(2)O = an alcohol + phosphate
- Gene Name:
- phoA
- Uniprot ID:
- P00634
- Molecular weight:
- 49438
Reactions
A phosphate monoester + H(2)O = an alcohol + phosphate. |
- General function:
- Involved in phosphoenolpyruvate carboxylase activity
- Specific function:
- Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
- Gene Name:
- ppc
- Uniprot ID:
- P00864
- Molecular weight:
- 99062
Reactions
Phosphate + oxaloacetate = H(2)O + phosphoenolpyruvate + HCO(3)(-). |
- General function:
- Involved in catalytic activity
- Specific function:
- Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
- Gene Name:
- aroH
- Uniprot ID:
- P00887
- Molecular weight:
- 38735
Reactions
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
- Gene Name:
- aroF
- Uniprot ID:
- P00888
- Molecular weight:
- 38804
Reactions
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L- serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction
- Gene Name:
- thrC
- Uniprot ID:
- P00934
- Molecular weight:
- 47113
Reactions
O-phospho-L-homoserine + H(2)O = L-threonine + phosphate. |
- General function:
- Involved in ATP binding
- Specific function:
- 2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate
- Gene Name:
- carB
- Uniprot ID:
- P00968
- Molecular weight:
- 117841
Reactions
2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate. |
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpA
- Uniprot ID:
- P03959
- Molecular weight:
- 59189
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpB
- Uniprot ID:
- P03960
- Molecular weight:
- 72198
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
- Gene Name:
- kdpC
- Uniprot ID:
- P03961
- Molecular weight:
- 20267
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in carboxyl- or carbamoyltransferase activity
- Specific function:
- Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
- Gene Name:
- argI
- Uniprot ID:
- P04391
- Molecular weight:
- 36907
Reactions
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. |
- General function:
- Involved in ATP binding
- Specific function:
- ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
- Gene Name:
- gshB
- Uniprot ID:
- P04425
- Molecular weight:
- 35561
Reactions
ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system
- Gene Name:
- rbsA
- Uniprot ID:
- P04983
- Molecular weight:
- 55041
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in RNA binding
- Specific function:
- Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction
- Gene Name:
- pnp
- Uniprot ID:
- P05055
- Molecular weight:
- 77100
Reactions
RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
- Gene Name:
- btuD
- Uniprot ID:
- P06611
- Molecular weight:
- 27081
Reactions
ATP + H(2)O + vitamin B12(Out) = ADP + phosphate + vitamin B12(In). |
- General function:
- Involved in carboxyl- or carbamoyltransferase activity
- Specific function:
- Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
- Gene Name:
- argF
- Uniprot ID:
- P06960
- Molecular weight:
- 36827
Reactions
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. |
- General function:
- Involved in catalytic activity
- Specific function:
- D-erythro-1-(imidazol-4-yl)glycerol 3- phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O
- Gene Name:
- hisB
- Uniprot ID:
- P06987
- Molecular weight:
- 40278
Reactions
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O. |
L-histidinol phosphate + H(2)O = L-histidinol + phosphate. |
- General function:
- Involved in oxidoreductase activity
- Specific function:
- Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate
- Gene Name:
- proA
- Uniprot ID:
- P07004
- Molecular weight:
- 44630
Reactions
L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH. |
- General function:
- Involved in hydrolase activity
- Specific function:
- Degradation of external UDP-glucose to uridine monophosphate and glucose-1-phosphate, which can then be used by the cell
- Gene Name:
- ushA
- Uniprot ID:
- P07024
- Molecular weight:
- 60824
Reactions
UDP-sugar + H(2)O = UMP + alpha-D-aldose 1-phosphate. |
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
- General function:
- Involved in acid phosphatase activity
- Specific function:
- A phosphate monoester + H(2)O = an alcohol + phosphate
- Gene Name:
- appA
- Uniprot ID:
- P07102
- Molecular weight:
- 47056
Reactions
A phosphate monoester + H(2)O = an alcohol + phosphate. |
Myo-inositol hexakisphosphate + H(2)O = 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate. |
- General function:
- Involved in 3-dehydroquinate synthase activity
- Specific function:
- 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate
- Gene Name:
- aroB
- Uniprot ID:
- P07639
- Molecular weight:
- 38881
Reactions
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. |
- General function:
- Involved in transferase activity, transferring glycosyl groups
- Specific function:
- The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
- Gene Name:
- deoA
- Uniprot ID:
- P07650
- Molecular weight:
- 47207
Reactions
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system
- Gene Name:
- fhuC
- Uniprot ID:
- P07821
- Molecular weight:
- 28886
Reactions
ATP + H(2)O + iron chelate(Out) = ADP + phosphate + iron chelate(In). |
- General function:
- Involved in ATP binding
- Specific function:
- Cell wall formation
- Gene Name:
- ddlB
- Uniprot ID:
- P07862
- Molecular weight:
- 32839
Reactions
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. |
- General function:
- Involved in catalytic activity
- Specific function:
- ATP + 2-(formamido)-N(1)-(5-phospho-D- ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D- ribosyl)imidazole
- Gene Name:
- purM
- Uniprot ID:
- P08178
- Molecular weight:
- 36854
Reactions
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. |
- General function:
- Involved in tetrahydrofolylpolyglutamate synthase activity
- Specific function:
- Conversion of folates to polyglutamate derivatives
- Gene Name:
- folC
- Uniprot ID:
- P08192
- Molecular weight:
- 45405
Reactions
ATP + tetrahydropteroyl-(gamma-Glu)(n) + L-glutamate = ADP + phosphate + tetrahydropteroyl-(gamma-Glu)(n+1). |
ATP + 7,8-dihydropteroate + L-glutamate = ADP + phosphate + 7,8-dihydropteroylglutamate. |
- General function:
- Involved in hydrolase activity
- Specific function:
- This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'- cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate
- Gene Name:
- cpdB
- Uniprot ID:
- P08331
- Molecular weight:
- 70832
Reactions
Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 3'-phosphate. |
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
- General function:
- Involved in phosphoribosylaminoimidazole carboxylase activity
- Specific function:
- Possesses an ATPase activity that is dependent on the presence of AIR (aminoimidazole ribonucleotide). The association of purK and purE produces an enzyme complex capable of converting AIR to CAIR efficiently under physiological condition
- Gene Name:
- purK
- Uniprot ID:
- P09029
- Molecular weight:
- 39461
Reactions
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole. |
- General function:
- Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups
- Specific function:
- Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
- Gene Name:
- aroA
- Uniprot ID:
- P0A6D3
- Molecular weight:
- 46095
Reactions
Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin
- Gene Name:
- ynfK
- Uniprot ID:
- P0A6E9
- Molecular weight:
- 24981
Reactions
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin. |
- General function:
- Involved in glutamine catabolic process
- Specific function:
- 2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate
- Gene Name:
- carA
- Uniprot ID:
- P0A6F1
- Molecular weight:
- 41431
Reactions
2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate. |
- General function:
- Involved in ATP binding
- Specific function:
- Cell wall formation
- Gene Name:
- ddlA
- Uniprot ID:
- P0A6J8
- Molecular weight:
- 39315
Reactions
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. |
- General function:
- Involved in glutamate-cysteine ligase activity
- Specific function:
- ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L-cysteine
- Gene Name:
- gshA
- Uniprot ID:
- P0A6W9
- Molecular weight:
- 58269
Reactions
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L-cysteine. |
- General function:
- Involved in catalytic activity
- Specific function:
- Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth
- Gene Name:
- kdsA
- Uniprot ID:
- P0A715
- Molecular weight:
- 30833
Reactions
Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. |
- General function:
- Involved in methylglyoxal synthase activity
- Specific function:
- Glycerone phosphate = methylglyoxal + phosphate
- Gene Name:
- mgsA
- Uniprot ID:
- P0A731
- Molecular weight:
- 16918
Reactions
Glycerone phosphate = methylglyoxal + phosphate. |
- General function:
- Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups
- Specific function:
- Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine. Target for the antibiotic phosphomycin
- Gene Name:
- murA
- Uniprot ID:
- P0A749
- Molecular weight:
- 44817
Reactions
Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. |
- General function:
- Involved in carboxyl- or carbamoyltransferase activity
- Specific function:
- Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate
- Gene Name:
- pyrB
- Uniprot ID:
- P0A786
- Molecular weight:
- 34427
Reactions
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
- Gene Name:
- pdxJ
- Uniprot ID:
- P0A794
- Molecular weight:
- 26384
Reactions
1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = pyridoxine 5'-phosphate + phosphate + 2 H(2)O. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- Diphosphate + H(2)O = 2 phosphate
- Gene Name:
- ppa
- Uniprot ID:
- P0A7A9
- Molecular weight:
- 19703
Reactions
Diphosphate + H(2)O = 2 phosphate. |
- General function:
- Involved in adenylosuccinate synthase activity
- Specific function:
- Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP
- Gene Name:
- purA
- Uniprot ID:
- P0A7D4
- Molecular weight:
- 47345
Reactions
GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP. |
- General function:
- Involved in ATP binding
- Specific function:
- ATP + 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate
- Gene Name:
- purC
- Uniprot ID:
- P0A7D7
- Molecular weight:
- 26995
Reactions
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. |
- General function:
- Involved in CTP synthase activity
- Specific function:
- Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen
- Gene Name:
- pyrG
- Uniprot ID:
- P0A7E5
- Molecular weight:
- 60374
Reactions
ATP + UTP + NH(3) = ADP + phosphate + CTP. |
- General function:
- Involved in methionine adenosyltransferase activity
- Specific function:
- Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. Is essential for growth
- Gene Name:
- metK
- Uniprot ID:
- P0A817
- Molecular weight:
- 41951
Reactions
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine. |
- General function:
- Involved in catalytic activity
- Specific function:
- Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. Requires selenophosphate as the selenium-donor molecule
- Gene Name:
- selA
- Uniprot ID:
- P0A821
- Molecular weight:
- 50607
Reactions
L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate. |
- General function:
- Involved in ATP binding
- Specific function:
- ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
- Gene Name:
- sucC
- Uniprot ID:
- P0A836
- Molecular weight:
- 41392
Reactions
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. |
- General function:
- Involved in hydrolase activity
- Specific function:
- Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain- length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. Also plays a significant physiological role in stress-response and is required for the survival of E.coli in stationary growth phase
- Gene Name:
- surE
- Uniprot ID:
- P0A840
- Molecular weight:
- 26900
Reactions
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Nucleotidase that shows high phosphatase activity toward three nucleoside 5'-monophosphates, UMP, dUMP, and dTMP, and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconate. Is strictly specific to substrates with 5'- phosphates and shows no activity against nucleoside 2'- or 3'- monophosphates. Might be involved in the pyrimidine nucleotide substrate cycles
- Gene Name:
- yjjG
- Uniprot ID:
- P0A8Y1
- Molecular weight:
- 25300
Reactions
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates erythrose 4-phosphate and mannose 1-phosphate
- Gene Name:
- yidA
- Uniprot ID:
- P0A8Y5
- Molecular weight:
- 29721
- General function:
- Involved in catalytic activity
- Specific function:
- Hydrolyzes phosphatidylglycerophosphate, phosphatidic acid, and lysophosphatidic acid; the pattern of activities varies according to subcellular location
- Gene Name:
- pgpB
- Uniprot ID:
- P0A924
- Molecular weight:
- 29021
Reactions
Phosphatidylglycerophosphate + H(2)O = phosphatidylglycerol + phosphate. |
- General function:
- Involved in phosphoric ester hydrolase activity
- Specific function:
- D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
- Gene Name:
- fbp
- Uniprot ID:
- P0A993
- Molecular weight:
- 36834
Reactions
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate. |
- General function:
- Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
- Specific function:
- D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH
- Gene Name:
- gapA
- Uniprot ID:
- P0A9B2
- Molecular weight:
- 35532
Reactions
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH. |
- General function:
- Involved in glutamate-ammonia ligase activity
- Specific function:
- ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine
- Gene Name:
- glnA
- Uniprot ID:
- P0A9C5
- Molecular weight:
- 51903
Reactions
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine. |
- General function:
- Involved in glycerol metabolic process
- Specific function:
- D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
- Gene Name:
- glpX
- Uniprot ID:
- P0A9C9
- Molecular weight:
- 35852
Reactions
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate. |
- General function:
- Involved in phosphate acetyltransferase activity
- Specific function:
- Acetyl-CoA + phosphate = CoA + acetyl phosphate
- Gene Name:
- pta
- Uniprot ID:
- P0A9M8
- Molecular weight:
- 77171
Reactions
Acetyl-CoA + phosphate = CoA + acetyl phosphate. |
- General function:
- Involved in acetyl-CoA carboxylase activity
- Specific function:
- Controls translation of mRNA for both itself and the alpha-subunit (accA) by binding to a probable hairpin in the 5' of the mRNA. Binding to mRNA inhibits translation; this is partially relieved by acetyl-CoA. Increasing amounts of mRNA also inhibit enzyme activity
- Gene Name:
- accD
- Uniprot ID:
- P0A9Q5
- Molecular weight:
- 33322
Reactions
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA. |
- General function:
- Involved in aspartate-semialdehyde dehydrogenase activity
- Specific function:
- L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH
- Gene Name:
- asd
- Uniprot ID:
- P0A9Q9
- Molecular weight:
- 40018
Reactions
L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH. |
- General function:
- Involved in protein tyrosine phosphatase activity
- Specific function:
- Dephosphorylates wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium
- Gene Name:
- wzb
- Uniprot ID:
- P0AAB2
- Molecular weight:
- 16709
Reactions
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system (Probable)
- Gene Name:
- araG
- Uniprot ID:
- P0AAF3
- Molecular weight:
- 55018
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)
- Gene Name:
- mglA
- Uniprot ID:
- P0AAG8
- Molecular weight:
- 56415
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex pstSACB involved in phosphate import. Responsible for energy coupling to the transport system
- Gene Name:
- pstB
- Uniprot ID:
- P0AAH0
- Molecular weight:
- 29027
Reactions
ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In). |
- General function:
- Involved in acylphosphatase activity
- Specific function:
- An acylphosphate + H(2)O = a carboxylate + phosphate
- Gene Name:
- yccX
- Uniprot ID:
- P0AB65
- Molecular weight:
- 10300
Reactions
An acylphosphate + H(2)O = a carboxylate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
- Gene Name:
- aroG
- Uniprot ID:
- P0AB91
- Molecular weight:
- 38009
Reactions
Phosphoenolpyruvate + D-erythrose 4-phosphate + H(2)O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. |
- General function:
- Involved in ATP binding
- Specific function:
- Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
- Gene Name:
- atpA
- Uniprot ID:
- P0ABB0
- Molecular weight:
- 55222
Reactions
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
- Gene Name:
- atpD
- Uniprot ID:
- P0ABB4
- Molecular weight:
- 50325
Reactions
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). |
- General function:
- Involved in hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- Specific function:
- Mediates magnesium influx to the cytosol
- Gene Name:
- mgtA
- Uniprot ID:
- P0ABB8
- Molecular weight:
- 99466
Reactions
ATP + H(2)O + Mg(2+)(Out) = ADP + phosphate + Mg(2+)(In). |
- General function:
- Involved in acetyl-CoA carboxylase activity
- Specific function:
- Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
- Gene Name:
- accA
- Uniprot ID:
- P0ABD5
- Molecular weight:
- 35241
Reactions
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA. |
- General function:
- Involved in purine-nucleoside phosphorylase activity
- Specific function:
- Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules
- Gene Name:
- deoD
- Uniprot ID:
- P0ABP8
- Molecular weight:
- 25950
Reactions
Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. |
- General function:
- Involved in 3-deoxy-manno-octulosonate-8-phosphatase activity
- Specific function:
- Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate
- Gene Name:
- kdsC
- Uniprot ID:
- P0ABZ4
- Molecular weight:
- 19997
Reactions
3-deoxy-D-manno-octulosonate 8-phosphate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate. |
- General function:
- Involved in phosphorylase activity
- Specific function:
- Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
- Gene Name:
- glgP
- Uniprot ID:
- P0AC86
- Molecular weight:
- 93172
Reactions
(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. |
- General function:
- Involved in protein tyrosine phosphatase activity
- Specific function:
- Dephosphorylates etk
- Gene Name:
- etp
- Uniprot ID:
- P0ACZ2
- Molecular weight:
- 16386
Reactions
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. |
- General function:
- Involved in phosphatidylinositol phosphorylation
- Specific function:
- Myo-inositol phosphate + H(2)O = myo-inositol + phosphate
- Gene Name:
- suhB
- Uniprot ID:
- P0ADG4
- Molecular weight:
- 29172
Reactions
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate. |
- General function:
- Involved in acid phosphatase activity
- Specific function:
- Dephosphorylates several organic phosphomonoesters and catalyzes the transfer of low-energy phosphate groups from phosphomonoesters to hydroxyl groups of various organic compounds. Preferentially acts on aryl phosphoesters. Might function as a broad-spectrum dephosphorylating enzyme able to scavenge both 3'- and 5'-nucleotides and also additional organic phosphomonoesters
- Gene Name:
- aphA
- Uniprot ID:
- P0AE22
- Molecular weight:
- 26103
Reactions
A phosphate monoester + H(2)O = an alcohol + phosphate. |
- General function:
- Amino acid transport and metabolism
- Specific function:
- Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine
- Gene Name:
- gsp
- Uniprot ID:
- P0AES0
- Molecular weight:
- 70531
Reactions
Glutathione + spermidine + ATP = glutathionylspermidine + ADP + phosphate. |
Glutathionylspermidine + H(2)O = glutathione + spermidine. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate of circa 500 residues long, while chains of circa 15 residues compete poorly with polyphosphate as substrate
- Gene Name:
- ppx
- Uniprot ID:
- P0AFL6
- Molecular weight:
- 58136
Reactions
(Polyphosphate)(n) + H(2)O = (polyphosphate)(n-1) + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- O-phospho-L(or D)-serine + H(2)O = L(or D)- serine + phosphate
- Gene Name:
- serB
- Uniprot ID:
- P0AGB0
- Molecular weight:
- 35042
Reactions
O-phospho-L(or D)-serine + H(2)O = L(or D)-serine + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
- Gene Name:
- sucD
- Uniprot ID:
- P0AGE9
- Molecular weight:
- 29777
Reactions
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
- Gene Name:
- ugpC
- Uniprot ID:
- P10907
- Molecular weight:
- 39524
Reactions
ATP + H(2)O + glycerol-3-phosphate(Out) = ADP + phosphate + glycerol-3-phosphate(In). |
- General function:
- Involved in N-acetyl-gamma-glutamyl-phosphate reductase activity
- Specific function:
- N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = N-acetyl-5-glutamyl phosphate + NADPH
- Gene Name:
- argC
- Uniprot ID:
- P11446
- Molecular weight:
- 35952
Reactions
N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. |
- General function:
- Involved in quinolinate synthetase A activity
- Specific function:
- Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
- Gene Name:
- nadA
- Uniprot ID:
- P11458
- Molecular weight:
- 38240
Reactions
Glycerone phosphate + iminosuccinate = pyridine-2,3-dicarboxylate + 2 H(2)O + phosphate. |
- General function:
- Involved in ATP binding
- Specific function:
- Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
- Gene Name:
- murF
- Uniprot ID:
- P11880
- Molecular weight:
- 47447
Reactions
ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine. |
- General function:
- Involved in chorismate synthase activity
- Specific function:
- 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
- Gene Name:
- aroC
- Uniprot ID:
- P12008
- Molecular weight:
- 39137
Reactions
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. |
- General function:
- Involved in transferase activity, transferring pentosyl groups
- Specific function:
- Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
- Gene Name:
- udp
- Uniprot ID:
- P12758
- Molecular weight:
- 27159
Reactions
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin
- Gene Name:
- bioD
- Uniprot ID:
- P13000
- Molecular weight:
- 24139
Reactions
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin. |
- General function:
- Involved in ATP binding
- Specific function:
- Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
- Gene Name:
- murD
- Uniprot ID:
- P14900
- Molecular weight:
- 46973
Reactions
ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. |
- General function:
- Involved in catalytic activity
- Specific function:
- ATP + N(2)-formyl-N(1)-(5-phospho-D- ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2- (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate
- Gene Name:
- purL
- Uniprot ID:
- P15254
- Molecular weight:
- 141402
Reactions
ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. |
- General function:
- Involved in ATP binding
- Specific function:
- ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide
- Gene Name:
- purD
- Uniprot ID:
- P15640
- Molecular weight:
- 45940
Reactions
ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide. |
- General function:
- Involved in catalytic activity
- Specific function:
- Synthesizes selenophosphate from selenide and ATP
- Gene Name:
- selD
- Uniprot ID:
- P16456
- Molecular weight:
- 36687
Reactions
ATP + selenide + H(2)O = AMP + selenophosphate + phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
- Gene Name:
- cysA
- Uniprot ID:
- P16676
- Molecular weight:
- 41059
Reactions
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In). |
- General function:
- Involved in ATP binding
- Specific function:
- Cell wall formation
- Gene Name:
- murC
- Uniprot ID:
- P17952
- Molecular weight:
- 53626
Reactions
ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine. |
- General function:
- Involved in phosphatidylglycerophosphatase activity
- Specific function:
- One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate
- Gene Name:
- pgpA
- Uniprot ID:
- P18200
- Molecular weight:
- 19418
Reactions
Phosphatidylglycerophosphate + H(2)O = phosphatidylglycerol + phosphate. |
- General function:
- Involved in acid phosphatase activity
- Specific function:
- Absolutely required for the growth of E.coli in a high- phosphate medium containing G-1-P as the sole carbon source
- Gene Name:
- agp
- Uniprot ID:
- P19926
- Molecular weight:
- 45683
Reactions
Alpha-D-glucose 1-phosphate + H(2)O = D-glucose + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate
- Gene Name:
- ybhA
- Uniprot ID:
- P21829
- Molecular weight:
- 30201
- General function:
- Involved in ATP binding
- Specific function:
- Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine
- Gene Name:
- murE
- Uniprot ID:
- P22188
- Molecular weight:
- 53343
Reactions
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diamino-heptanedioate. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Has 10000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2)
- Gene Name:
- cysQ
- Uniprot ID:
- P22255
- Molecular weight:
- 27176
Reactions
Adenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
- Gene Name:
- ppsA
- Uniprot ID:
- P23538
- Molecular weight:
- 87434
Reactions
ATP + pyruvate + H(2)O = AMP + phosphoenolpyruvate + phosphate. |
- General function:
- Involved in ligase activity
- Specific function:
- This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
- Gene Name:
- accC
- Uniprot ID:
- P24182
- Molecular weight:
- 49320
Reactions
ATP + biotin-[carboxyl-carrier-protein] + CO(2) = ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein]. |
ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA. |
- General function:
- Involved in guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity
- Specific function:
- Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities
- Gene Name:
- gppA
- Uniprot ID:
- P25552
- Molecular weight:
- 54871
Reactions
Guanosine 5'-triphosphate,3'-diphosphate + H(2)O = guanosine 3',5'-bis(diphosphate) + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Removes the phosphate from trehalose 6-phosphate to produce free trehalose
- Gene Name:
- otsB
- Uniprot ID:
- P31678
- Molecular weight:
- 29175
Reactions
Trehalose 6-phosphate + H(2)O = trehalose + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress
- Gene Name:
- gph
- Uniprot ID:
- P32662
- Molecular weight:
- 27389
Reactions
2-phosphoglycolate + H(2)O = glycolate + phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex AlsBAC involved in D-allose import. Probably responsible for energy coupling to the transport system
- Gene Name:
- alsA
- Uniprot ID:
- P32721
- Molecular weight:
- 56744
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in transferase activity, transferring selenium-containing groups
- Specific function:
- Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
- Gene Name:
- selU
- Uniprot ID:
- P33667
- Molecular weight:
- 41110
Reactions
5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system
- Gene Name:
- ccmA
- Uniprot ID:
- P33931
- Molecular weight:
- 23053
Reactions
ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system
- Gene Name:
- fbpC
- Uniprot ID:
- P37009
- Molecular weight:
- 39059
Reactions
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system (Probable). The XylFGH system can also transport ribose in absence of xylose
- Gene Name:
- xylG
- Uniprot ID:
- P37388
- Molecular weight:
- 56470
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Involved in export of lead, cadmium, zinc and mercury
- Gene Name:
- zntA
- Uniprot ID:
- P37617
- Molecular weight:
- 76839
Reactions
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out). |
ATP + H(2)O + Zn(2+)(In) = ADP + phosphate + Zn(2+)(Out). |
- General function:
- Involved in catalytic activity
- Specific function:
- Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin
- Gene Name:
- cobC
- Uniprot ID:
- P52086
- Molecular weight:
- 23308
Reactions
Adenosylcobalamin 5'-phosphate + H(2)O = coenzyme B12 + phosphate. |
Alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage
- Gene Name:
- fliI
- Uniprot ID:
- P52612
- Molecular weight:
- 49315
Reactions
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). |
- General function:
- Involved in hydrolase activity
- Specific function:
- Plays a key role in signaling protein misfolding via the cpxR/CPXA transducing system. It also modulates the phosphorylated status of many phosphoproteins in E.coli, some of which acting as major chaperones. Has been shown, in vitro, to act on Ser, Thr and Tyr-phosphorylated substrates
- Gene Name:
- pphA
- Uniprot ID:
- P55798
- Molecular weight:
- 25274
Reactions
A phosphoprotein + H(2)O = a protein + phosphate. |
- General function:
- Involved in hydrolase activity
- Specific function:
- Has been shown, in vitro, to act on Ser, Thr and Tyr- phosphorylated substrates
- Gene Name:
- pphB
- Uniprot ID:
- P55799
- Molecular weight:
- 25098
Reactions
A phosphoprotein + H(2)O = a protein + phosphate. |
- General function:
- Involved in undecaprenyl-diphosphatase activity
- Specific function:
- Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
- Gene Name:
- uppP
- Uniprot ID:
- P60932
- Molecular weight:
- 29758
Reactions
Undecaprenyl diphosphate + H(2)O = undecaprenyl phosphate + phosphate. |
- General function:
- Involved in riboflavin biosynthetic process
- Specific function:
- Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino- 2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4- phosphate yielding 6,7-dimethyl-8-lumazine
- Gene Name:
- ribH
- Uniprot ID:
- P61714
- Molecular weight:
- 16156
Reactions
2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system
- Gene Name:
- malK
- Uniprot ID:
- P68187
- Molecular weight:
- 40990
Reactions
ATP + H(2)O + maltose(Out) = ADP + phosphate + maltose(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system
- Gene Name:
- potA
- Uniprot ID:
- P69874
- Molecular weight:
- 43028
Reactions
ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In). |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo
- Gene Name:
- supH
- Uniprot ID:
- P75792
- Molecular weight:
- 30413
Reactions
Sugar phosphate + H(2)O = sugar + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo
- Gene Name:
- ybjG
- Uniprot ID:
- P75806
- Molecular weight:
- 22398
Reactions
Undecaprenyl diphosphate + H(2)O = undecaprenyl phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Sucrose + phosphate = D-fructose + alpha-D- glucose 1-phosphate
- Gene Name:
- ycjM
- Uniprot ID:
- P76041
- Molecular weight:
- 64185
Reactions
Sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- 2(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2(alpha-D-mannosyl)-D-glycerate + phosphate
- Gene Name:
- yedP
- Uniprot ID:
- P76329
- Molecular weight:
- 30439
Reactions
2(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Nucleotidase that shows strict specificity toward deoxyribonucleoside 5'-monophosphates and does not dephosphorylate 5'-ribonucleotides or ribonucleoside 3'-monophosphates. Might be involved in the regulation of all dNTP pools in E.coli
- Gene Name:
- yfbR
- Uniprot ID:
- P76491
- Molecular weight:
- 22708
Reactions
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate. |
- General function:
- Involved in glutamate-ammonia ligase activity
- Specific function:
- Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine
- Gene Name:
- puuA
- Uniprot ID:
- P78061
- Molecular weight:
- 53177
Reactions
ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Involved in copper export. May also be involved in silver export
- Gene Name:
- copA
- Uniprot ID:
- Q59385
- Molecular weight:
- 87872
Reactions
ATP + H(2)O + Cu(+)(In) = ADP + phosphate + Cu(+)(Out). |
- General function:
- Involved in phosphatase activity
- Specific function:
- Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position
- Gene Name:
- gmhB
- Uniprot ID:
- P63228
- Molecular weight:
- 21294
Reactions
D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(2)O = D-glycero-beta-D-manno-heptose 1-phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Specific function unknown
- Gene Name:
- yigL
- Uniprot ID:
- P27848
- Molecular weight:
- 29708
Reactions
Pyridoxal 5'-phosphate + H(2)O = pyridoxal + phosphate. |
Sugar phosphate + H(2)O = sugar + phosphate. |
- General function:
- Involved in glycerol metabolic process
- Specific function:
- Specific function unknown
- Gene Name:
- yggF
- Uniprot ID:
- P21437
- Molecular weight:
- 34323
Reactions
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate. |
- General function:
- Involved in catalytic activity
- Specific function:
- Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
- Gene Name:
- plsX
- Uniprot ID:
- P27247
- Molecular weight:
- 38214
Reactions
Acyl-[acyl-carrier-protein] + phosphate = acyl-phosphate + [acyl-carrier-protein]. |
- General function:
- Involved in nucleoside-triphosphatase activity
- Specific function:
- Specific function unknown
- Gene Name:
- yjjX
- Uniprot ID:
- P39411
- Molecular weight:
- 18213
Reactions
A nucleoside triphosphate + H(2)O = a nucleoside diphosphate + monophosphate. |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
- Gene Name:
- nikD
- Uniprot ID:
- P33593
- Molecular weight:
- 26820
Reactions
ATP + H(2)O + Ni(2+)(Out) = ADP + phosphate + Ni(2+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
- Gene Name:
- nikE
- Uniprot ID:
- P33594
- Molecular weight:
- 29721
Reactions
ATP + H(2)O + Ni(2+)(Out) = ADP + phosphate + Ni(2+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
- Gene Name:
- tauB
- Uniprot ID:
- Q47538
- Molecular weight:
- 28297
Reactions
ATP + H(2)O + taurine(Out) = ADP + phosphate + taurine(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
- Gene Name:
- modC
- Uniprot ID:
- P09833
- Molecular weight:
- 39102
Reactions
ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In). |
- General function:
- Involved in argininosuccinate synthase activity
- Specific function:
- Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
- Gene Name:
- queC
- Uniprot ID:
- P77756
- Molecular weight:
- 25514
Reactions
7-carboxy-7-carbaguanine + NH(3) + ATP = 7-cyano-7-carbaguanine + ADP + phosphate + H(2)O. |
- General function:
- Not Available
- Specific function:
- Not Available
- Gene Name:
- yniC
- Uniprot ID:
- P77247
- Molecular weight:
- Not Available
- General function:
- Not Available
- Specific function:
- Not Available
- Gene Name:
- yfbT
- Uniprot ID:
- P77625
- Molecular weight:
- Not Available
- General function:
- Replication, recombination and repair
- Specific function:
- Has a helix-destabilizing activity, which is not coupled to the ATPase activity. Can unwind the 23S rRNA as well as 16S rRNA. Exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA. Could play a major role in ribosome assembly, specifically in the assembly process of the active center of 50S ribosomal subunits
- Gene Name:
- dbpA
- Uniprot ID:
- P21693
- Molecular weight:
- 49187
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Acts in 50S ribosomal subunit biogenesis at low temperatures, acting after srmB. Has a helix-destabilizing activity; however it is unclear whether it requires ATP:according to PubMed:8552679, it does not require ATP, while according to PubMed:15196029 and PubMed:15554978, it requires ATP. Requires a helicase substrate with a single-stranded overhang. Plays a key role in optimal cell growth at low temperature and is required for normal cell division. When overexpressed suppresses cold-sensitive mutants of the rpsB gene (ribosomal protein S2) and of the smbA2 cold-sensitive mutant (pyrH, uridylate kinase). Can replace rhlB, another ATP-dependent RNA helicase, in the RNA degradosome in vitro. Stimulates translation, probably at the level of initiation, of some mRNAs
- Gene Name:
- deaD
- Uniprot ID:
- P0A9P6
- Molecular weight:
- 70546
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Transcription
- Specific function:
- Probable helicase involved in DNA repair and perhaps also replication
- Gene Name:
- dinG
- Uniprot ID:
- P27296
- Molecular weight:
- 81439
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins
- Gene Name:
- dnaB
- Uniprot ID:
- P0ACB0
- Molecular weight:
- 52390
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Helicase IV catalyzes the unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand in a reaction that is dependent upon the hydrolysis of ATP
- Gene Name:
- helD
- Uniprot ID:
- P15038
- Molecular weight:
- 77976
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Not yet known
- Gene Name:
- hrpA
- Uniprot ID:
- P43329
- Molecular weight:
- 149027
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- ATP + H(2)O = ADP + phosphate
- Gene Name:
- hrpB
- Uniprot ID:
- P37024
- Molecular weight:
- 89147
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Carbohydrate transport and metabolism
- Specific function:
- Not Available
- Gene Name:
- yjeF
- Uniprot ID:
- P31806
- Molecular weight:
- 54650
Reactions
ADP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide = AMP + phosphate + NADH. |
(R)-NADHX = (S)-NADHX. |
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system
- Gene Name:
- phnC
- Uniprot ID:
- P16677
- Molecular weight:
- 29430
Reactions
ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In). |
- General function:
- Replication, recombination and repair
- Specific function:
- Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. recG unwind branched duplex DNA (Y-DNA). Has a role in constitutive stable DNA replication (csdR) and R-loop formation
- Gene Name:
- recG
- Uniprot ID:
- P24230
- Molecular weight:
- 76430
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase
- Gene Name:
- recQ
- Uniprot ID:
- P15043
- Molecular weight:
- 68363
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction
- Gene Name:
- rep
- Uniprot ID:
- P09980
- Molecular weight:
- 77024
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Can carry out ATP-dependent unwinding of double stranded RNA. Has a role in RNA decay. Involved in the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
- Gene Name:
- rhlB
- Uniprot ID:
- P0A8J8
- Molecular weight:
- 47125
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- Acts as an ATP-dependent RNA helicase, able to unwind ds-RNA
- Gene Name:
- rhlE
- Uniprot ID:
- P25888
- Molecular weight:
- 49989
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of ruvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA
- Gene Name:
- ruvA
- Uniprot ID:
- P0A809
- Molecular weight:
- 22086
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing
- Gene Name:
- ruvB
- Uniprot ID:
- P0A812
- Molecular weight:
- 37173
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Replication, recombination and repair
- Specific function:
- RNA-dependent ATPase activity. Acts in 50S ribosomal subunit biogenesis at low temperatures, acting before deaD/csdA. Suppressor of a mutant defective in 50S ribosomal subunit assembly. Probably interacts with 23S ribosomal RNA
- Gene Name:
- srmB
- Uniprot ID:
- P21507
- Molecular weight:
- 49914
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Involved in tRNA binding
- Specific function:
- Not Available
- Gene Name:
- ypfI
- Uniprot ID:
- P76562
- Molecular weight:
- 74892
Reactions
(Elongator tRNA(Met))-cytidine(34) + ATP + acetyl-CoA = (elongator tRNA(Met))-N(4)-acetylcytidine(34) + ADP + phosphate + CoA. |
- General function:
- Replication, recombination and repair
- Specific function:
- Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair
- Gene Name:
- uvrD
- Uniprot ID:
- P03018
- Molecular weight:
- 81989
Reactions
ATP + H(2)O = ADP + phosphate. |
- General function:
- Translation, ribosomal structure and biogenesis
- Specific function:
- ATP + H(2)O = ADP + phosphate
- Gene Name:
- yoaA
- Uniprot ID:
- P76257
- Molecular weight:
- 70377
Reactions
ATP + H(2)O = ADP + phosphate. |
Transporters
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpA
- Uniprot ID:
- P03959
- Molecular weight:
- 59189
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpB
- Uniprot ID:
- P03960
- Molecular weight:
- 72198
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
- Gene Name:
- kdpC
- Uniprot ID:
- P03961
- Molecular weight:
- 20267
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system
- Gene Name:
- rbsA
- Uniprot ID:
- P04983
- Molecular weight:
- 55041
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
- Gene Name:
- btuD
- Uniprot ID:
- P06611
- Molecular weight:
- 27081
Reactions
ATP + H(2)O + vitamin B12(Out) = ADP + phosphate + vitamin B12(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system
- Gene Name:
- fhuC
- Uniprot ID:
- P07821
- Molecular weight:
- 28886
Reactions
ATP + H(2)O + iron chelate(Out) = ADP + phosphate + iron chelate(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system (Probable)
- Gene Name:
- araG
- Uniprot ID:
- P0AAF3
- Molecular weight:
- 55018
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)
- Gene Name:
- mglA
- Uniprot ID:
- P0AAG8
- Molecular weight:
- 56415
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex pstSACB involved in phosphate import. Responsible for energy coupling to the transport system
- Gene Name:
- pstB
- Uniprot ID:
- P0AAH0
- Molecular weight:
- 29027
Reactions
ATP + H(2)O + phosphate(Out) = ADP + phosphate + phosphate(In). |
- General function:
- Involved in ATP binding
- Specific function:
- Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
- Gene Name:
- atpA
- Uniprot ID:
- P0ABB0
- Molecular weight:
- 55222
Reactions
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
- Gene Name:
- atpD
- Uniprot ID:
- P0ABB4
- Molecular weight:
- 50325
Reactions
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
- Gene Name:
- ugpC
- Uniprot ID:
- P10907
- Molecular weight:
- 39524
Reactions
ATP + H(2)O + glycerol-3-phosphate(Out) = ADP + phosphate + glycerol-3-phosphate(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
- Gene Name:
- cysA
- Uniprot ID:
- P16676
- Molecular weight:
- 41059
Reactions
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex AlsBAC involved in D-allose import. Probably responsible for energy coupling to the transport system
- Gene Name:
- alsA
- Uniprot ID:
- P32721
- Molecular weight:
- 56744
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system
- Gene Name:
- fbpC
- Uniprot ID:
- P37009
- Molecular weight:
- 39059
Reactions
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system (Probable). The XylFGH system can also transport ribose in absence of xylose
- Gene Name:
- xylG
- Uniprot ID:
- P37388
- Molecular weight:
- 56470
Reactions
ATP + H(2)O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system
- Gene Name:
- malK
- Uniprot ID:
- P68187
- Molecular weight:
- 40990
Reactions
ATP + H(2)O + maltose(Out) = ADP + phosphate + maltose(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system
- Gene Name:
- potA
- Uniprot ID:
- P69874
- Molecular weight:
- 43028
Reactions
ATP + H(2)O + polyamine(Out) = ADP + phosphate + polyamine(In). |
- General function:
- Involved in inorganic phosphate transmembrane transporter activity
- Specific function:
- Low-affinity inorganic phosphate transport. Can also transport arsenate
- Gene Name:
- pitA
- Uniprot ID:
- P0AFJ7
- Molecular weight:
- 53389
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
- Gene Name:
- nikD
- Uniprot ID:
- P33593
- Molecular weight:
- 26820
Reactions
ATP + H(2)O + Ni(2+)(Out) = ADP + phosphate + Ni(2+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system
- Gene Name:
- nikE
- Uniprot ID:
- P33594
- Molecular weight:
- 29721
Reactions
ATP + H(2)O + Ni(2+)(Out) = ADP + phosphate + Ni(2+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
- Gene Name:
- tauB
- Uniprot ID:
- Q47538
- Molecular weight:
- 28297
Reactions
ATP + H(2)O + taurine(Out) = ADP + phosphate + taurine(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
- Gene Name:
- modC
- Uniprot ID:
- P09833
- Molecular weight:
- 39102
Reactions
ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In). |
- General function:
- Inorganic ion transport and metabolism
- Specific function:
- Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system
- Gene Name:
- phnC
- Uniprot ID:
- P16677
- Molecular weight:
- 29430
Reactions
ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In). |