2.0 2012-07-30 14:55:05 -0600 2015-10-02 02:25:53 -0600 ECMDB21238 M2MDB001646 L-Threonine O-3-phosphate In E. coli, acid phosphatase / phosphotransferase and alkaline phosphatase are the enzymes that catalyze the chemical reaction L-threonine 3-O-phosphate[periplasmic space] + H2O[periplasmic space] -> L-threonine[periplasmic space] + phosphate[periplasmic space], where L-Threonine O-3-phosphate is a substrate (EcoCyc compound: L-THREONINE-O-3-PHOSPHATE). (2S,3R)-2-amino-3-hydroxybutanoate (2S,3R)-2-amino-3-hydroxybutanoate 3-phosphate (2S,3R)-2-amino-3-hydroxybutanoic acid (2S,3R)-2-amino-3-hydroxybutanoic acid 3-phosphate (2S,3R)-2-amino-3-Hydroxybutanoic acid 3-phosphoric acid L-Threonine O-3-phosphate L-Threonine O-3-phosphoric acid L-Threonine O-phosphate L-Threonine O-phosphoric acid L-Threonine phosphate L-Threonine phosphoric acid O-Phospho-L-threonine O-Phosphono-L-threonine O3-phosphothreonine Phospho-L-threonine Phosphothreonine Synonyms Sources Threonine phosphate ester Threonine phosphoric acid ester Threoninium dihydrogen phosphate Threoninium dihydrogen phosphoric acid C4H10NO6P 199.0991 199.024573569 (2S,3R)-2-amino-3-(phosphonooxy)butanoic acid phosphothreonine 1114-81-4 C[C@@H](OP(O)(O)=O)[C@H](N)C(O)=O InChI=1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1 USRGIUJOYOXOQJ-GBXIJSLDSA-N Solid Extra-organism Periplasm logp -1.86 ALOGPS logs -0.93 ALOGPS solubility 2.35e+01 g/l ALOGPS logp -2.7 ChemAxon pka_strongest_acidic 1.21 ChemAxon pka_strongest_basic 9.47 ChemAxon iupac (2S,3R)-2-amino-3-(phosphonooxy)butanoic acid ChemAxon average_mass 199.0991 ChemAxon mono_mass 199.024573569 ChemAxon smiles C[C@@H](OP(O)(O)=O)[C@H](N)C(O)=O ChemAxon formula C4H10NO6P ChemAxon inchi InChI=1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1 ChemAxon inchikey USRGIUJOYOXOQJ-GBXIJSLDSA-N ChemAxon polar_surface_area 130.08 ChemAxon refractivity 37.33 ChemAxon polarizability 15.43 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 23789 Specdb::CMs 39592 Specdb::CMs 138005 Specdb::CMs 145739 Specdb::NmrOneD 93292 Specdb::NmrOneD 93293 Specdb::NmrOneD 93294 Specdb::NmrOneD 93295 Specdb::NmrOneD 93296 Specdb::NmrOneD 93297 Specdb::NmrOneD 93298 Specdb::NmrOneD 93299 Specdb::NmrOneD 93300 Specdb::NmrOneD 93301 Specdb::NmrOneD 93302 Specdb::NmrOneD 93303 Specdb::NmrOneD 93304 Specdb::NmrOneD 93305 Specdb::NmrOneD 93306 Specdb::NmrOneD 93307 Specdb::NmrOneD 93308 Specdb::NmrOneD 93309 Specdb::NmrOneD 93310 Specdb::NmrOneD 93311 Specdb::MsMs 28613 Specdb::MsMs 28614 Specdb::MsMs 28615 Specdb::MsMs 35171 Specdb::MsMs 35172 Specdb::MsMs 35173 Specdb::MsMs 2757513 Specdb::MsMs 2757514 Specdb::MsMs 2757515 Specdb::MsMs 2947995 Specdb::MsMs 2947996 Specdb::MsMs 2947997 HMDB11185 3246323 2497038 C12147 37525 L-THREONINE-O-3-PHOSPHATE TPO van der Werf, M. J., Overkamp, K. M., Muilwijk, B., Coulier, L., Hankemeier, T. (2007). "Microbial metabolomics: toward a platform with full metabolome coverage." Anal Biochem 370:17-25. 17765195 Kataoka, H., Nakai, K., Katagiri, Y., Makita, M. (1993). "Analysis of free and bound O-phosphoamino acids in urine by gas chromatography with flame photometric detection." Biomed Chromatogr 7:184-188. 7693088 http://hmdb.ca/system/metabolites/msds/000/009/915/original/HMDB11185.pdf?1358461243 Class B acid phosphatase P0AE22 APHA_ECOLI aphA http://ecmdb.ca/proteins/P0AE22.xml Outer membrane protein N P77747 OMPN_ECOLI ompN http://ecmdb.ca/proteins/P77747.xml Outer membrane pore protein E P02932 PHOE_ECOLI phoE http://ecmdb.ca/proteins/P02932.xml Outer membrane protein F P02931 OMPF_ECOLI ompF http://ecmdb.ca/proteins/P02931.xml Outer membrane protein C P06996 OMPC_ECOLI ompC http://ecmdb.ca/proteins/P06996.xml Water + L-Threonine O-3-phosphate > Phosphate + L-Threonine