2.0 2012-05-31 14:49:56 -0600 2015-06-03 17:20:11 -0600 ECMDB20544 M2MDB001351 D-Ribulose-1-phosphate D-ribulose-1-phosphate is a pentose phosphate. Pentoses are monosaccharides in which the carbohydrate moiety contains five carbon atoms. D-RIBULOSE-1-P D-Ribulose-1-phosphoric acid C5H11O8P 230.1098 230.01915384 [(3,4,5-trihydroxy-2-oxopentyl)oxy]phosphonic acid (3,4,5-trihydroxy-2-oxopentyl)oxyphosphonic acid OCC(O)C(O)C(=O)COP(O)(O)=O InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h3,5-7,9H,1-2H2,(H2,10,11,12) NBOCCPQHBPGYCX-UHFFFAOYSA-N Cytoplasm Periplasm logp -1.80 ALOGPS logs -0.97 ALOGPS solubility 2.47e+01 g/l ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 1.18 ChemAxon pka_strongest_basic -3 ChemAxon iupac [(3,4,5-trihydroxy-2-oxopentyl)oxy]phosphonic acid ChemAxon average_mass 230.1098 ChemAxon mono_mass 230.01915384 ChemAxon smiles OCC(O)C(O)C(=O)COP(O)(O)=O ChemAxon formula C5H11O8P ChemAxon inchi InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h3,5-7,9H,1-2H2,(H2,10,11,12) ChemAxon inchikey NBOCCPQHBPGYCX-UHFFFAOYSA-N ChemAxon polar_surface_area 144.52 ChemAxon refractivity 42.47 ChemAxon polarizability 18.07 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 7 ChemAxon donor_count 5 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon D-arabinose degradation I E. coli K-12 uses the enzymes of the fucose degradation pathway for utilization of D-arabinose. Expression of the enzymes in this pathway is normally induced by L-fucose and not by D-arabinose; thus, wild-type E. coli K-12 can not use D-arabinose as a sole source of carbon and energy without prior induction by growth on L-fucose. Growth on D-arabinose requires a mutation in the transcriptional regulator FucR. D-arabinose is metabolized yielding dihydroxy-acetone phosphate, an intermediate of glycolysis, which thereby enters central metabolism, and glycolaldehyde. Glycolaldehyde may be further catabolized to glycolate. (EcoCyc) PW002038 Metabolic D-arabinose degradation I DARABCATK12-PWY Specdb::CMs 112174 Specdb::CMs 125584 Specdb::CMs 1006488 Specdb::CMs 1006489 Specdb::CMs 1006490 Specdb::CMs 1006491 Specdb::CMs 1006492 Specdb::CMs 1006493 Specdb::CMs 1006494 Specdb::CMs 1006495 Specdb::CMs 1006496 Specdb::CMs 1006497 Specdb::CMs 1006498 Specdb::CMs 1006499 Specdb::CMs 1006500 Specdb::CMs 1006501 Specdb::CMs 1006502 Specdb::CMs 1006503 Specdb::CMs 1006504 Specdb::CMs 1006505 Specdb::CMs 1006506 Specdb::CMs 1006507 Specdb::CMs 1006508 Specdb::CMs 1006509 Specdb::CMs 1006510 Specdb::NmrOneD 245188 Specdb::NmrOneD 245189 Specdb::NmrOneD 245190 Specdb::NmrOneD 245191 Specdb::NmrOneD 245192 Specdb::NmrOneD 245193 Specdb::NmrOneD 245194 Specdb::NmrOneD 245195 Specdb::NmrOneD 245196 Specdb::NmrOneD 245197 Specdb::NmrOneD 245198 Specdb::NmrOneD 245199 Specdb::NmrOneD 245200 Specdb::NmrOneD 245201 Specdb::NmrOneD 245202 Specdb::NmrOneD 245203 Specdb::NmrOneD 245204 Specdb::NmrOneD 245205 Specdb::NmrOneD 245206 Specdb::NmrOneD 245207 Specdb::MsMs 23780 Specdb::MsMs 23781 Specdb::MsMs 23782 Specdb::MsMs 30578 Specdb::MsMs 30579 Specdb::MsMs 30580 615 595 D-RIBULOSE-1-P Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. 21097882 van der Werf, M. J., Overkamp, K. M., Muilwijk, B., Coulier, L., Hankemeier, T. (2007). "Microbial metabolomics: toward a platform with full metabolome coverage." Anal Biochem 370:17-25. 17765195 Winder, C. L., Dunn, W. B., Schuler, S., Broadhurst, D., Jarvis, R., Stephens, G. M., Goodacre, R. (2008). "Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites." Anal Chem 80:2939-2948. 18331064 L-fuculose phosphate aldolase P0AB87 FUCA_ECOLI fucA http://ecmdb.ca/proteins/P0AB87.xml L-fuculokinase P11553 FUCK_ECOLI fucK http://ecmdb.ca/proteins/P11553.xml D-Ribulose-1-phosphate <> Glycolaldehyde + Dihydroxyacetone phosphate DARABALDOL-RXN D-Ribulose + Adenosine triphosphate > Hydrogen ion + D-Ribulose-1-phosphate + ADP DARABKIN-RXN D-Ribulose + Adenosine triphosphate + D-Ribulose > Adenosine diphosphate + Hydrogen ion + D-Ribulose-1-phosphate + ADP PW_R003841 D-Ribulose-1-phosphate <> Glycolaldehyde + Glycerone phosphate PW_R005956 D-Ribulose + Adenosine triphosphate > D-Ribulose-1-phosphate + Adenosine monophosphate + Hydrogen ion PW_R005955