2.0 2012-05-31 14:36:46 -0600 2015-09-16 14:50:11 -0600 ECMDB20276 M2MDB001116 O-Phospho-D-serine O-phospho-D-serine is a phosphoric ester of serine and phosphoric acid. Phosphorylated serine residues are often referred to as phosphoserine. Phosphoserine is a component of many proteins. The phosphorylation of the alcohol functional group in serine to produce phosphoserine is catalyzed by various types of kinases. Free phosphoserine may be found after proteins have been proteolyzed. Phosphoserine phosphatase is able to dephosphorylate phosphoserince (both L and D forms). (2S)-2-amino-3-phosphonooxypropanoate (2S)-2-amino-3-phosphonooxypropanoic acid 2-Amino-3-(phosphonooxy)propanoate 2-Amino-3-(phosphonooxy)propanoic acid 3-P-Serine 3-Phospho-1-serine 3-Phospho-L-serine 3-Phospho-serine 3-Phosphoserine D -2-Amino-3-hydroxypropanoate 3-phosphate D -2-Amino-3-hydroxypropanoic acid 3-phosphate D -2-amino-3-Hydroxypropanoic acid 3-phosphoric acid D-O-Phosphoserine DL-2-Amino-3-hydroxypropanoate 3-phosphate DL-2-Amino-3-hydroxypropanoic acid 3-phosphate DL-2-amino-3-Hydroxypropanoic acid 3-phosphoric acid DL-O-phosphorylserine DL-O-phosphoserine DL-O-serine phosphate DL-O-Serine phosphoric acid DL-phosphoserine DL-serine dihydrogen phosphate DL-Serine dihydrogen phosphoric acid DL-Serine monophosphate DL-serine monophosphorate DL-serine monophosphoric acid DL-serine, dihydrogen phosphate (ester) DL-Serine, dihydrogen phosphoric acid (ester) DL-sop Energoserina L-Serine, dihydrogen phosphate L-Serine, dihydrogen phosphoric acid O-Phospho-DL-serine O-Phospho-L-serine O-Phosphono-Serine O-Phosphonoserine O-Phosphoserine P-Ser P-Serine Phosphonoserine Phosphorylserine Phosphoserine Serine phosphate Serine phosphoric acid Serine, dihydrogen phosphate (ester) (9CI) Serine, dihydrogen phosphate (ester), DL- (8CI) Serine, dihydrogen phosphoric acid (ester) (9ci) Serine, dihydrogen phosphoric acid (ester), DL- (8ci) Serine-3-p Serine-3-phosphate Serine-3-phosphoric acid Serophen Seryl phosphate Seryl phosphoric acid [1-14c] Serine Dihydrogen Phosphate (ester) [1-14C] Serine dihydrogen phosphoric acid (ester) C3H8NO6P 185.0725 185.008923505 (2R)-2-amino-3-(phosphonooxy)propanoic acid O-phospho-D-serine 17885-08-4 [H][C@@](N)(COP(O)(O)=O)C(O)=O InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m1/s1 BZQFBWGGLXLEPQ-UWTATZPHSA-N Solid Cytoplasm Periplasm logp -2.32 ALOGPS logs -0.97 ALOGPS solubility 1.99e+01 g/l ALOGPS melting_point 228 oC logp -3.2 ChemAxon pka_strongest_acidic 1.2 ChemAxon pka_strongest_basic 9.39 ChemAxon iupac (2R)-2-amino-3-(phosphonooxy)propanoic acid ChemAxon average_mass 185.0725 ChemAxon mono_mass 185.008923505 ChemAxon smiles [H][C@@](N)(COP(O)(O)=O)C(O)=O ChemAxon formula C3H8NO6P ChemAxon inchi InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m1/s1 ChemAxon inchikey BZQFBWGGLXLEPQ-UWTATZPHSA-N ChemAxon polar_surface_area 130.08 ChemAxon refractivity 32.91 ChemAxon polarizability 14.06 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon Glycine, serine and threonine metabolism ec00260 Methane metabolism ec00680 Microbial metabolism in diverse environments ec01120 Metabolic pathways eco01100 Specdb::CMs 1085320 Specdb::NmrOneD 333678 Specdb::NmrOneD 333679 Specdb::NmrOneD 333680 Specdb::NmrOneD 333681 Specdb::NmrOneD 333682 Specdb::NmrOneD 333683 Specdb::NmrOneD 333684 Specdb::NmrOneD 333685 Specdb::NmrOneD 333686 Specdb::NmrOneD 333687 Specdb::NmrOneD 333688 Specdb::NmrOneD 333689 Specdb::NmrOneD 333690 Specdb::NmrOneD 333691 Specdb::NmrOneD 333692 Specdb::NmrOneD 333693 Specdb::NmrOneD 333694 Specdb::NmrOneD 333695 Specdb::NmrOneD 333696 Specdb::NmrOneD 333697 Specdb::MsMs 25097 Specdb::MsMs 25098 Specdb::MsMs 25099 Specdb::MsMs 31655 Specdb::MsMs 31656 Specdb::MsMs 31657 Specdb::MsMs 3608065 Specdb::MsMs 3608066 Specdb::MsMs 3608067 Specdb::MsMs 3608068 Specdb::MsMs 3608069 Specdb::MsMs 3608070 106 388807 C02532 37713 CPD-3722 Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. 21097882 Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. 22080510 Phosphoserine phosphatase P0AGB0 SERB_ECOLI serB http://ecmdb.ca/proteins/P0AGB0.xml O-Phospho-D-serine + Water > L-Serine + Inorganic phosphate Phosphoserine + O-Phospho-D-serine + Water <> L-Serine + D-Serine + Phosphate R00582 R02853