2.0 2012-05-31 14:34:03 -0600 2015-06-03 17:19:34 -0600 ECMDB20225 M2MDB001070 2-Deoxy-D-glucose 6-phosphate 2-deoxyglucose-6-phosphate is a sugar phosphate. It is a substrate for 2-deoxyglucose-6-phosphatase (EC 3.1.3.68) which is an enzyme that catalyzes the chemical reaction 2-deoxy-D-glucose 6-phosphate + H2O <-> 2-deoxy-D-glucose + phosphate The two substrates of this enzyme are 2-deoxy-D-glucose 6-phosphate and H2O, whereas its two products are 2-deoxy-D-glucose and phosphate. 2-deoxyglucose-6-phosphatase or YniC is a sugar phosphatase belonging to the superfamily of haloacid dehalogenase (HAD)-like hydrolases. (2R,3S,4R)-3,4,6-trihydroxyoxan-2-ylmethyl dihydrogen phosphate (2R,3S,4R)-3,4,6-Trihydroxyoxan-2-ylmethyl dihydrogen phosphoric acid 2-Deoxy-6-O-phospho-D-glucopyranose 2-Deoxy-D-glucose 6-phosphoric acid C6H13O8P 244.1364 244.034803904 {[(2R,3S,4R)-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid 2-deoxy-D-glucose 6-phosphate 56-73-5 [H]C1(O)C[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(COP(O)(O)=O)O1 InChI=1S/C6H13O8P/c7-3-1-5(8)14-4(6(3)9)2-13-15(10,11)12/h3-9H,1-2H2,(H2,10,11,12)/t3-,4-,5?,6+/m1/s1 UQJFZAAGZAYVKZ-CERMHHMHSA-N Liquid Cytoplasm Periplasm logp -2.07 ALOGPS logs -0.86 ALOGPS solubility 3.34e+01 g/l ALOGPS logp -2.2 ChemAxon pka_strongest_acidic 1.22 ChemAxon pka_strongest_basic -3.3 ChemAxon iupac {[(2R,3S,4R)-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid ChemAxon average_mass 244.1364 ChemAxon mono_mass 244.034803904 ChemAxon smiles [H]C1(O)C[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(COP(O)(O)=O)O1 ChemAxon formula C6H13O8P ChemAxon inchi InChI=1S/C6H13O8P/c7-3-1-5(8)14-4(6(3)9)2-13-15(10,11)12/h3-9H,1-2H2,(H2,10,11,12)/t3-,4-,5?,6+/m1/s1 ChemAxon inchikey UQJFZAAGZAYVKZ-CERMHHMHSA-N ChemAxon polar_surface_area 136.68 ChemAxon refractivity 45.29 ChemAxon polarizability 20.19 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 7 ChemAxon donor_count 5 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon inner membrane transport list of inner membrane transport complexes, transporting compounds from the periplasmic space to the cytosol This pathway should be updated regularly with the new inner membrae transports added PW000786 Metabolic Specdb::CMs 1084850 Specdb::NmrOneD 331582 Specdb::NmrOneD 331583 Specdb::NmrOneD 331584 Specdb::NmrOneD 331585 Specdb::NmrOneD 331586 Specdb::NmrOneD 331587 Specdb::NmrOneD 331588 Specdb::NmrOneD 331589 Specdb::NmrOneD 331590 Specdb::NmrOneD 331591 Specdb::NmrOneD 331592 Specdb::NmrOneD 331593 Specdb::NmrOneD 331594 Specdb::NmrOneD 331595 Specdb::NmrOneD 331596 Specdb::NmrOneD 331597 Specdb::NmrOneD 331598 Specdb::NmrOneD 331599 Specdb::NmrOneD 331600 Specdb::NmrOneD 331601 Specdb::MsMs 24824 Specdb::MsMs 24825 Specdb::MsMs 24826 Specdb::MsMs 31382 Specdb::MsMs 31383 Specdb::MsMs 31384 440992 389817 C06369 16043 2-DEOXY-D-GLUCOSE-6-PHOSPHATE PTS system mannose-specific EIIAB component P69797 PTNAB_ECOLI manX http://ecmdb.ca/proteins/P69797.xml Mannose permease IIC component P69801 PTNC_ECOLI manY http://ecmdb.ca/proteins/P69801.xml Mannose permease IID component P69805 PTND_ECOLI manZ http://ecmdb.ca/proteins/P69805.xml 2-deoxyglucose-6-P phosphatase P77247 yniC http://ecmdb.ca/proteins/P77247.xml Mannose permease IIC component P69801 PTNC_ECOLI manY http://ecmdb.ca/proteins/P69801.xml Mannose permease IID component P69805 PTND_ECOLI manZ http://ecmdb.ca/proteins/P69805.xml Water + 2-Deoxy-D-glucose 6-phosphate > Phosphate + 2-Deoxyglucose 3.1.3.68-RXN 2-Deoxy-D-glucose 6-phosphate + Water > 2-Deoxyglucose + Inorganic phosphate 2-Deoxyglucose + HPr - phosphorylated > 2-Deoxy-D-glucose 6-phosphate + HPr PW_RCT000178