Record Information |
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Version | 2.0 |
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Creation Date | 2012-05-31 14:27:00 -0600 |
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Update Date | 2015-06-03 17:19:17 -0600 |
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Secondary Accession Numbers | |
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Identification |
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Name: | 4-Hydroxy-L-threonine |
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Description | 4-hydroxy-L-threonine is a member of the chemical class known as Alpha Amino Acids and Derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).4-hydroxyl-L-threonine is involved in pyridoxine biosynthesis. This result is consistent with a model in which 4-phospho-hydroxy-L-threonine (synonym, 3-hydroxyhomoserine phosphate), rather than 4-hydroxy-L-threonine, is an obligatory intermediate in pyridoxal 5'-phosphate biosynthesis. (PMID 8595869) |
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Structure | |
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Synonyms: | - (2S,3S)-2-amino-3,4-dihydroxybutanoate
- (2S,3S)-2-amino-3,4-dihydroxybutanoic acid
- 2-Amino-3,4-dihydroxy-(S-(R*,R*))-L-Threonate
- 2-Amino-3,4-dihydroxy-(S-(R*,R*))-L-Threonic acid
- 3-Hydroxyhomoserine
- a-amino-b,g-Dihydroxybutyrate
- a-amino-b,g-Dihydroxybutyric acid
- Alpha-Amino-beta,gamma-dihydroxybutyrate
- Alpha-Amino-beta,gamma-dihydroxybutyric acid
- Hydroxythreonine
- α-amino-β,γ-Dihydroxybutyrate
- α-amino-β,γ-Dihydroxybutyric acid
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Chemical Formula: | C4H9NO4 |
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Weight: | Average: 135.1186 Monoisotopic: 135.053157781 |
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InChI Key: | JBNUARFQOCGDRK-GBXIJSLDSA-N |
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InChI: | InChI=1S/C4H9NO4/c5-3(4(8)9)2(7)1-6/h2-3,6-7H,1,5H2,(H,8,9)/t2-,3+/m1/s1 |
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CAS number: | 21768-45-6 |
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IUPAC Name: | (2S,3S)-2-amino-3,4-dihydroxybutanoic acid |
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Traditional IUPAC Name: | hydroxythreonine |
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SMILES: | N[C@@H]([C@H](O)CO)C(O)=O |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
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Kingdom | Organic compounds |
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Super Class | Organic acids and derivatives |
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Class | Carboxylic acids and derivatives |
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Sub Class | Amino acids, peptides, and analogues |
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Direct Parent | L-alpha-amino acids |
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Alternative Parents | |
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Substituents | - L-alpha-amino acid
- Beta-hydroxy acid
- Short-chain hydroxy acid
- Hydroxy acid
- Fatty acid
- 1,3-aminoalcohol
- 1,2-diol
- Amino acid
- Secondary alcohol
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Organic nitrogen compound
- Primary alcohol
- Organooxygen compound
- Organonitrogen compound
- Primary amine
- Primary aliphatic amine
- Hydrocarbon derivative
- Organic oxide
- Carbonyl group
- Organopnictogen compound
- Amine
- Alcohol
- Organic oxygen compound
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Physical Properties |
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State: | Not Available |
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Charge: | 0 |
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Melting point: | Not Available |
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Experimental Properties: | |
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Predicted Properties | |
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Biological Properties |
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Cellular Locations: | Cytoplasm |
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Reactions: | |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | |
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EcoCyc Pathways: | Not Available |
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Concentrations |
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| Not Available |
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Spectra |
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Spectra: | |
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References |
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References: | - Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. Pubmed: 22080510
- Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
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Synthesis Reference: | Not Available |
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Material Safety Data Sheet (MSDS) | Not Available |
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Links |
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External Links: | |
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