Potassium (ECMDB04139) (M2MDB000632)
Record Information | |||||||||||||||||||||||||||||||||||||||||||||||||
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Version | 2.0 | ||||||||||||||||||||||||||||||||||||||||||||||||
Creation Date | 2012-05-31 14:06:15 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||
Update Date | 2015-09-13 12:56:14 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||
Secondary Accession Numbers |
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Identification | |||||||||||||||||||||||||||||||||||||||||||||||||
Name: | Potassium | ||||||||||||||||||||||||||||||||||||||||||||||||
Description | Potassium is an essential electrolyte and part of many minerals. Potassium ion is a major intracellular cation in bacteria, plants and animals. It is necessary for the function of all living cells. There are a number of of potassium transport systems that regulate the intracellular potassium concentration. | ||||||||||||||||||||||||||||||||||||||||||||||||
Structure | |||||||||||||||||||||||||||||||||||||||||||||||||
Synonyms: |
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Chemical Formula: | K | ||||||||||||||||||||||||||||||||||||||||||||||||
Weight: | Average: 39.0983 Monoisotopic: 38.963706861 | ||||||||||||||||||||||||||||||||||||||||||||||||
InChI Key: | NPYPAHLBTDXSSS-UHFFFAOYSA-N | ||||||||||||||||||||||||||||||||||||||||||||||||
InChI: | InChI=1S/K/q+1 | ||||||||||||||||||||||||||||||||||||||||||||||||
CAS number: | 7440-09-7 | ||||||||||||||||||||||||||||||||||||||||||||||||
IUPAC Name: | potassium(1+) ion | ||||||||||||||||||||||||||||||||||||||||||||||||
Traditional IUPAC Name: | potassium(1+) ion | ||||||||||||||||||||||||||||||||||||||||||||||||
SMILES: | [K+] | ||||||||||||||||||||||||||||||||||||||||||||||||
Chemical Taxonomy | |||||||||||||||||||||||||||||||||||||||||||||||||
Description | belongs to the class of inorganic compounds known as homogeneous alkali metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkali metal atom. | ||||||||||||||||||||||||||||||||||||||||||||||||
Kingdom | Inorganic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
Super Class | Homogeneous metal compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
Class | Homogeneous alkali metal compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
Sub Class | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
Direct Parent | Homogeneous alkali metal compounds | ||||||||||||||||||||||||||||||||||||||||||||||||
Alternative Parents | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
Substituents |
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Molecular Framework | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
External Descriptors |
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Physical Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
State: | Solid | ||||||||||||||||||||||||||||||||||||||||||||||||
Charge: | 1 | ||||||||||||||||||||||||||||||||||||||||||||||||
Melting point: | 63.2 °C | ||||||||||||||||||||||||||||||||||||||||||||||||
Experimental Properties: |
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Predicted Properties |
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Biological Properties | |||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Locations: | Cytoplasm | ||||||||||||||||||||||||||||||||||||||||||||||||
Reactions: | ADP + Phosphate + 4 Hydrogen ion + Heme + Nickel(2+) + Iron chelate + Taurine + Molybdate + Magnesium + Fe3+ + Potassium + Polyamine + vitamin B12 + Sulfate + glycerol-3-phosphate + Phosphonate + D-Maltose <> Adenosine triphosphate +3 Hydrogen ion + Water Adenosine triphosphate + Water + Potassium > ADP + Hydrogen ion + Potassium + Phosphate Adenosine triphosphate + Water + Potassium > ADP + Hydrogen ion + Potassium + Phosphate Potassium + Water + Adenosine triphosphate > Potassium + Phosphate + ADP + Hydrogen ion Potassium + Water + Adenosine triphosphate > Potassium + Phosphate + ADP + Hydrogen ion | ||||||||||||||||||||||||||||||||||||||||||||||||
SMPDB Pathways: |
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KEGG Pathways: | |||||||||||||||||||||||||||||||||||||||||||||||||
EcoCyc Pathways: | Not Available | ||||||||||||||||||||||||||||||||||||||||||||||||
Concentrations | |||||||||||||||||||||||||||||||||||||||||||||||||
Find out more about how we convert literature concentrations. | |||||||||||||||||||||||||||||||||||||||||||||||||
Spectra | |||||||||||||||||||||||||||||||||||||||||||||||||
Spectra: |
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References | |||||||||||||||||||||||||||||||||||||||||||||||||
References: |
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Synthesis Reference: | Alberti, Augusto. Recovering potassium salts from the refuse liquor of the manufacture of tartaric acid. (1910), US 957295 19100510 CAN 4:13164 AN 1910:13164 | ||||||||||||||||||||||||||||||||||||||||||||||||
Material Safety Data Sheet (MSDS) | Download (PDF) | ||||||||||||||||||||||||||||||||||||||||||||||||
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External Links: |
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Enzymes
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpA
- Uniprot ID:
- P03959
- Molecular weight:
- 59189
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpB
- Uniprot ID:
- P03960
- Molecular weight:
- 72198
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
- Gene Name:
- kdpC
- Uniprot ID:
- P03961
- Molecular weight:
- 20267
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Not Available
- Specific function:
- Specific function unknown
- Gene Name:
- kdpF
- Uniprot ID:
- P36937
- Molecular weight:
- 3072
Transporters
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpA
- Uniprot ID:
- P03959
- Molecular weight:
- 59189
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in nucleotide binding
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
- Gene Name:
- kdpB
- Uniprot ID:
- P03960
- Molecular weight:
- 72198
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in potassium-transporting ATPase activity
- Specific function:
- One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
- Gene Name:
- kdpC
- Uniprot ID:
- P03961
- Molecular weight:
- 20267
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In). |
- General function:
- Involved in transmembrane transport
- Specific function:
- Efflux pump driven by the proton motive force. Confers resistance to basic, aromatic and lipophilic drugs as well as neutral, non-aromatic, zwitterionic or non-aromatic hydrophilic antibiotics
- Gene Name:
- cmr
- Uniprot ID:
- P0AEY8
- Molecular weight:
- 44320
- General function:
- Involved in cation transmembrane transporter activity
- Specific function:
- Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system
- Gene Name:
- trkG
- Uniprot ID:
- P23849
- Molecular weight:
- 53943
- General function:
- Involved in cation transmembrane transporter activity
- Specific function:
- According to PubMed:8496184 the natural activity of this protein is as a calcium/proton antiporter, but it can act as a weak sodium/proton antiporter. The presence of a preferred substrate and normal pH cytoplasmic values might prevent significant sodium/proton antiporter activity
- Gene Name:
- chaA
- Uniprot ID:
- P31801
- Molecular weight:
- 39168
- General function:
- Involved in potassium ion transmembrane transporter activity
- Specific function:
- Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium
- Gene Name:
- kup
- Uniprot ID:
- P63183
- Molecular weight:
- 69293
- General function:
- Involved in cation transmembrane transporter activity
- Specific function:
- Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH
- Gene Name:
- trkA
- Uniprot ID:
- P0AGI8
- Molecular weight:
- 50367
- General function:
- Involved in transporter activity
- Specific function:
- Non-specific porin
- Gene Name:
- ompN
- Uniprot ID:
- P77747
- Molecular weight:
- 41220
- General function:
- Involved in transporter activity
- Specific function:
- Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
- Gene Name:
- phoE
- Uniprot ID:
- P02932
- Molecular weight:
- 38922
- General function:
- Involved in cation transmembrane transporter activity
- Specific function:
- Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity
- Gene Name:
- trkH
- Uniprot ID:
- P0AFZ7
- Molecular weight:
- 52959
- General function:
- Involved in nucleotide binding
- Specific function:
- Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides
- Gene Name:
- sapD
- Uniprot ID:
- P0AAH4
- Molecular weight:
- 37660
- General function:
- Involved in solute:hydrogen antiporter activity
- Specific function:
- Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport
- Gene Name:
- kefC
- Uniprot ID:
- P03819
- Molecular weight:
- 67795
- General function:
- Involved in transporter activity
- Specific function:
- OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
- Gene Name:
- ompF
- Uniprot ID:
- P02931
- Molecular weight:
- 39333
- General function:
- Involved in solute:hydrogen antiporter activity
- Specific function:
- Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport
- Gene Name:
- kefB
- Uniprot ID:
- P45522
- Molecular weight:
- 66411
- General function:
- Not Available
- Specific function:
- Specific function unknown
- Gene Name:
- kdpF
- Uniprot ID:
- P36937
- Molecular weight:
- 3072
- General function:
- Involved in transporter activity
- Specific function:
- Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
- Gene Name:
- ompC
- Uniprot ID:
- P06996
- Molecular weight:
- 40368
- General function:
- Involved in nucleotide binding
- Specific function:
- May play a role in the defense against osmotic shock
- Gene Name:
- kch
- Uniprot ID:
- P31069
- Molecular weight:
- 46062