L-Glutamine (ECMDB00641) (M2MDB000163)

General function:

Involved in asparaginase activity

Specific function:

L-asparagine + H(2)O = L-aspartate + NH(3)

Gene Name:

ansB

Uniprot ID:

P00805

Molecular weight:

36851

Reactions

General function:

Involved in biosynthetic process

Specific function:

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate

Gene Name:

trpE

Uniprot ID:

P00895

Molecular weight:

57494

Reactions

General function:

Involved in metabolic process

Specific function:

Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine

Gene Name:

pabA

Uniprot ID:

P00903

Molecular weight:

20772

Reactions

General function:

Involved in anthranilate phosphoribosyltransferase activity

Specific function:

Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate

Gene Name:

trpD

Uniprot ID:

P00904

Molecular weight:

56869

Reactions

General function:

Involved in nucleotide binding

Specific function:

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)

Gene Name:

glnS

Uniprot ID:

P00962

Molecular weight:

63477

Reactions

General function:

Involved in ATP binding

Specific function:

2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate

Gene Name:

carB

Uniprot ID:

P00968

Molecular weight:

117841

Reactions

General function:

Involved in GMP synthase (glutamine-hydrolyzing) activity

Specific function:

Catalyzes the synthesis of GMP from XMP

Gene Name:

guaA

Uniprot ID:

P04079

Molecular weight:

58679

Reactions

General function:

Involved in biosynthetic process

Specific function:

Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine

Gene Name:

pabB

Uniprot ID:

P05041

Molecular weight:

50969

Reactions

General function:

Involved in catalytic activity

Specific function:

2 L-glutamate + NADP(+) = L-glutamine + 2- oxoglutarate + NADPH

Gene Name:

gltB

Uniprot ID:

P09831

Molecular weight:

166708

Reactions

General function:

Involved in iron-sulfur cluster binding

Specific function:

2 L-glutamate + NADP(+) = L-glutamine + 2- oxoglutarate + NADPH

Gene Name:

gltD

Uniprot ID:

P09832

Molecular weight:

52015

Reactions

General function:

Involved in glutamine catabolic process

Specific function:

2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate

Gene Name:

carA

Uniprot ID:

P0A6F1

Molecular weight:

41431

Reactions

General function:

Involved in glutaminase activity

Specific function:

L-glutamine + H(2)O = L-glutamate + NH(3)

Gene Name:

glsA2

Uniprot ID:

P0A6W0

Molecular weight:

33515

Reactions

General function:

Involved in CTP synthase activity

Specific function:

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen

Gene Name:

pyrG

Uniprot ID:

P0A7E5

Molecular weight:

60374

Reactions

General function:

Involved in glutamate-ammonia ligase activity

Specific function:

ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine

Gene Name:

glnA

Uniprot ID:

P0A9C5

Molecular weight:

51903

Reactions

General function:

Involved in amidophosphoribosyltransferase activity

Specific function:

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O

Gene Name:

purF

Uniprot ID:

P0AG16

Molecular weight:

56488

Reactions

General function:

Involved in catalytic activity

Specific function:

ATP + N(2)-formyl-N(1)-(5-phospho-D- ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2- (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate

Gene Name:

purL

Uniprot ID:

P15254

Molecular weight:

141402

Reactions

General function:

Involved in metabolic process

Specific function:

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source

Gene Name:

glmS

Uniprot ID:

P17169

Molecular weight:

66894

Reactions

General function:

Involved in NAD+ synthase (glutamine-hydrolyzing) activity

Specific function:

Catalyzes a key step in NAD biosynthesis, transforming deamido-NAD into NAD by a two-step reaction

Gene Name:

nadE

Uniprot ID:

P18843

Molecular weight:

30637

Reactions

General function:

Involved in asparagine synthase (glutamine-hydrolyzing) activity

Specific function:

ATP + L-aspartate + L-glutamine + H(2)O = AMP + diphosphate + L-asparagine + L-glutamate

Gene Name:

asnB

Uniprot ID:

P22106

Molecular weight:

62659

Reactions

General function:

Involved in glutaminase activity

Specific function:

L-glutamine + H(2)O = L-glutamate + NH(3)

Gene Name:

glsA1

Uniprot ID:

P77454

Molecular weight:

32903

Reactions

General function:

Involved in glutamate-ammonia ligase activity

Specific function:

Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine

Gene Name:

puuA

Uniprot ID:

P78061

Molecular weight:

53177

Reactions

General function:

Involved in transporter activity

Specific function:

Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane

Gene Name:

glnP

Uniprot ID:

P0AEQ6

Molecular weight:

24364

General function:

Involved in nucleotide binding

Specific function:

Part of the binding-protein-dependent transport system for glutamine. Probably responsible for energy coupling to the transport system

Gene Name:

glnQ

Uniprot ID:

P10346

Molecular weight:

26731

General function:

Involved in transferase activity, transferring pentosyl groups

Specific function:

IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to hisF for the synthesis of IGP and AICAR

Gene Name:

hisH

Uniprot ID:

P60595

Molecular weight:

21653

Reactions

General function:

Involved in catalytic activity

Specific function:

IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the hisH subunit

Gene Name:

hisF

Uniprot ID:

P60664

Molecular weight:

28454

Reactions

General function:

Involved in transporter activity

Specific function:

Involved in a glutamine-transport system glnHPQ

Gene Name:

glnH

Uniprot ID:

P0AEQ3

Molecular weight:

27190