Fumaric acid (ECMDB00176) (M2MDB000073)

General function:

Involved in electron carrier activity

Specific function:

Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth

Gene Name:

frdA

Uniprot ID:

P00363

Molecular weight:

65971

Reactions

General function:

Involved in fumarate hydratase activity

Specific function:

(S)-malate = fumarate + H(2)O

Gene Name:

fumC

Uniprot ID:

P05042

Molecular weight:

50488

Reactions

General function:

Involved in electron carrier activity

Specific function:

Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth

Gene Name:

sdhB

Uniprot ID:

P07014

Molecular weight:

26770

Reactions

General function:

Involved in catalytic activity

Specific function:

(S)-dihydroorotate + a quinone = orotate + a quinol

Gene Name:

pyrD

Uniprot ID:

P0A7E1

Molecular weight:

36774

Reactions

General function:

Energy production and conversion

Specific function:

Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

Gene Name:

frdC

Uniprot ID:

P0A8Q0

Molecular weight:

15015

General function:

Involved in fumarate metabolic process

Specific function:

Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

Gene Name:

frdD

Uniprot ID:

P0A8Q3

Molecular weight:

13107

General function:

Involved in N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

Specific function:

N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP

Gene Name:

purB

Uniprot ID:

P0AB89

Molecular weight:

51542

Reactions

General function:

Involved in lyase activity

Specific function:

It functions as an aerobic enzyme in the citric acid cycle. It accounts for about 80% of the fumarase activity when the bacteria grows aerobically

Gene Name:

fumA

Uniprot ID:

P0AC33

Molecular weight:

60298

Reactions

General function:

Involved in aspartate ammonia-lyase activity

Specific function:

L-aspartate = fumarate + NH(3)

Gene Name:

aspA

Uniprot ID:

P0AC38

Molecular weight:

52356

Reactions

General function:

Involved in electron carrier activity

Specific function:

Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth

Gene Name:

sdhA

Uniprot ID:

P0AC41

Molecular weight:

64421

Reactions

General function:

Involved in succinate dehydrogenase activity

Specific function:

Membrane-anchoring subunit of succinate dehydrogenase (SDH)

Gene Name:

sdhD

Uniprot ID:

P0AC44

Molecular weight:

12867

General function:

Involved in electron carrier activity

Specific function:

Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth

Gene Name:

frdB

Uniprot ID:

P0AC47

Molecular weight:

27123

Reactions

General function:

Involved in FMN binding

Specific function:

Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Does not use oxygen directly. Is coupled to the respiratory chain

Gene Name:

hemG

Uniprot ID:

P0ACB4

Molecular weight:

21226

Reactions

General function:

Involved in electron carrier activity

Specific function:

Catalyzes the oxidation of L-aspartate to iminoaspartate

Gene Name:

nadB

Uniprot ID:

P10902

Molecular weight:

60337

Reactions

General function:

Involved in argininosuccinate lyase activity

Specific function:

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine

Gene Name:

argH

Uniprot ID:

P11447

Molecular weight:

50318

Reactions

General function:

Involved in lyase activity

Specific function:

It functions in the generation of fumarate for use as an anaerobic electron acceptor

Gene Name:

fumB

Uniprot ID:

P14407

Molecular weight:

60105

Reactions

General function:

Involved in succinate dehydrogenase activity

Specific function:

Membrane-anchoring subunit of succinate dehydrogenase (SDH)

Gene Name:

sdhC

Uniprot ID:

P69054

Molecular weight:

14299

General function:

Involved in catalytic activity

Specific function:

Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid

Gene Name:

mhpC

Uniprot ID:

P77044

Molecular weight:

32585

Reactions