D-Glucose (ECMDB00122) (M2MDB000045)

General function:

Involved in beta-galactosidase activity

Specific function:

Hydrolysis of terminal non-reducing beta-D- galactose residues in beta-D-galactosides

Gene Name:

lacZ

Uniprot ID:

P00722

Molecular weight:

116482

Reactions

General function:

Involved in xylose isomerase activity

Specific function:

D-xylose = D-xylulose

Gene Name:

xylA

Uniprot ID:

P00944

Molecular weight:

49742

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Hydrolysis of terminal, non-reducing alpha-D- galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids

Gene Name:

melA

Uniprot ID:

P06720

Molecular weight:

50657

Reactions

General function:

Involved in beta-galactosidase activity

Specific function:

The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme

Gene Name:

ebgA

Uniprot ID:

P06864

Molecular weight:

117878

Reactions

General function:

Involved in transferase activity, transferring phosphorus-containing groups

Specific function:

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)

Gene Name:

ptsI

Uniprot ID:

P08839

Molecular weight:

63561

Reactions

General function:

Involved in glucokinase activity

Specific function:

Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate

Gene Name:

glk

Uniprot ID:

P0A6V8

Molecular weight:

34723

Reactions

General function:

Involved in nucleotide binding

Specific function:

Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)

Gene Name:

mglA

Uniprot ID:

P0AAG8

Molecular weight:

56415

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Can hydrolyze salicin and arbutin

Gene Name:

bglB

Uniprot ID:

P11988

Molecular weight:

53161

Reactions

General function:

Involved in catalytic activity

Specific function:

Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system

Gene Name:

treA

Uniprot ID:

P13482

Molecular weight:

63636

Reactions

General function:

Involved in oxidoreductase activity, acting on CH-OH group of donors

Specific function:

GDH is probably involved in energy conservation rather than in sugar metabolism

Gene Name:

gcd

Uniprot ID:

P15877

Molecular weight:

86747

Reactions

General function:

Involved in 4-alpha-glucanotransferase activity

Specific function:

Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan

Gene Name:

malQ

Uniprot ID:

P15977

Molecular weight:

78503

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Hydrolyzes a wide variety of P-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, gentiobiose-6P, methyl- beta-glucoside-6P and p-nitrophenyl-beta-D-glucopyranoside-6P. Is also able to hydrolyze phospho-N,N'-diacetylchitobiose

Gene Name:

chbF

Uniprot ID:

P17411

Molecular weight:

50512

Reactions

General function:

Involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

Specific function:

MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system

Gene Name:

malX

Uniprot ID:

P19642

Molecular weight:

56627

Reactions

General function:

Involved in acid phosphatase activity

Specific function:

Absolutely required for the growth of E.coli in a high- phosphate medium containing G-1-P as the sole carbon source

Gene Name:

agp

Uniprot ID:

P19926

Molecular weight:

45683

Reactions

General function:

Involved in catalytic activity

Specific function:

May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units

Gene Name:

malZ

Uniprot ID:

P21517

Molecular weight:

69172

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Can hydrolyze salicin, cellobiose, and probably arbutin

Gene Name:

ascB

Uniprot ID:

P24240

Molecular weight:

53935

Reactions

General function:

Involved in catalytic activity

Specific function:

Alpha,alpha-trehalose 6-phosphate + H(2)O = D- glucose + D-glucose 6-phosphate

Gene Name:

treC

Uniprot ID:

P28904

Molecular weight:

63837

Reactions

General function:

Involved in catalytic activity

Specific function:

Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed

Gene Name:

yihQ

Uniprot ID:

P32138

Molecular weight:

77274

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

Hydrolysis of terminal, non-reducing beta-D- glucosyl residues with release of beta-D-glucose

Gene Name:

bglX

Uniprot ID:

P33363

Molecular weight:

83459

Reactions

General function:

Involved in catalytic activity

Specific function:

Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity

Gene Name:

treF

Uniprot ID:

P62601

Molecular weight:

63696

Reactions

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport

Gene Name:

crr

Uniprot ID:

P69783

Molecular weight:

18251

Reactions

General function:

Involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. This enzyme is also a chemoreceptor monitoring the environment for changes in sugar concentration

Gene Name:

ptsG

Uniprot ID:

P69786

Molecular weight:

50676

Reactions

General function:

Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport

Gene Name:

manX

Uniprot ID:

P69797

Molecular weight:

35047

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo

Gene Name:

supH

Uniprot ID:

P75792

Molecular weight:

30413

Reactions

General function:

Involved in transferase activity

Specific function:

Acetylates maltose and other sugars

Gene Name:

maa

Uniprot ID:

P77791

Molecular weight:

20096

Reactions

General function:

Involved in hydrolase activity, hydrolyzing O-glycosyl compounds

Specific function:

6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H(2)O = D-glucose + D-glucose 6-phosphate

Gene Name:

bglA

Uniprot ID:

Q46829

Molecular weight:

55361

Reactions

General function:

Involved in transporter activity

Specific function:

Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane

Gene Name:

mglC

Uniprot ID:

P23200

Molecular weight:

35550

General function:

Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport

Gene Name:

manY

Uniprot ID:

P69801

Molecular weight:

27636

General function:

Involved in phosphoenolpyruvate-dependent sugar phosphotransferase system

Specific function:

The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport

Gene Name:

manZ

Uniprot ID:

P69805

Molecular weight:

31303

General function:

Carbohydrate transport and metabolism

Specific function:

This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor

Gene Name:

mglB

Uniprot ID:

P0AEE5

Molecular weight:

35712

General function:

Involved in oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor

Specific function:

Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such as maltose, maltotriose or cellobiose. It may function to input sugar-derived electrons into the respiratory network

Gene Name:

yliI

Uniprot ID:

P75804

Molecular weight:

41054

General function:

Involved in sugar:hydrogen symporter activity

Specific function:

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III)

Gene Name:

ptsH

Uniprot ID:

P0AA04

Molecular weight:

9119

Reactions

General function:

carbohydrate metabolic process

Specific function:

Not Available

Gene Name:

lacZ

Uniprot ID:

G0ZKW2

Molecular weight:

116482

Reactions