Acetic acid (ECMDB00042) (M2MDB000012)
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Version | 2.0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Creation Date | 2012-05-31 09:55:48 -0600 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Update Date | 2015-09-13 12:56:05 -0600 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Secondary Accession Numbers |
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Identification | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Name: | Acetic acid | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Description | Acetic acid is one of the simplest carboxylic acids. The acetyl group, derived from acetic acid, is fundamental to the biochemistry of virtually all forms of life. When bound to coenzyme A it forms acetyl-CoA, which is central to the metabolism of carbohydrates and fats. However, the concentration of free acetic acid in cells is kept at a low level to avoid disrupting the control of the pH of the cell contents. Acetic acid is produced and excreted by certain bacteria, notably the Acetobacter genus and Clostridium acetobutylicum. These bacteria are found universally in foodstuffs, water, and soil, and acetic acid is produced naturally as fruits and some other foods spoil. (Wikipedia) Acetic acid, or more accurately, acetate, a derivative of acetic acid, can be produced by E. coli through fermentation in glucose metabolism. (KEGG, PMID 18600996) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Structure | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Synonyms: |
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Chemical Formula: | C2H4O2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Weight: | Average: 60.052 Monoisotopic: 60.021129372 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
InChI Key: | QTBSBXVTEAMEQO-UHFFFAOYSA-N | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
InChI: | InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CAS number: | 64-19-7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IUPAC Name: | acetic acid | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Traditional IUPAC Name: | acetic acid | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SMILES: | CC(O)=O | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Chemical Taxonomy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Description | belongs to the class of organic compounds known as carboxylic acids. Carboxylic acids are compounds containing a carboxylic acid group with the formula -C(=O)OH. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Kingdom | Organic compounds | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Super Class | Organic acids and derivatives | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Class | Carboxylic acids and derivatives | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sub Class | Carboxylic acids | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Direct Parent | Carboxylic acids | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Alternative Parents | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Substituents |
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Molecular Framework | Aliphatic acyclic compounds | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
External Descriptors |
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Physical Properties | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
State: | Liquid | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Charge: | -1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Melting point: | 16.6 °C | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Experimental Properties: |
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Predicted Properties |
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Biological Properties | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Locations: | Cytoplasm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Reactions: | Citric acid <> Acetic acid + Oxalacetic acid Acetoacetic acid + Acetyl-CoA > Acetoacetyl-CoA + Acetic acid Acetyl-CoA + Butyric acid > Acetic acid + Butyryl-CoA Acetyl-CoA + Hexanoate (N-C6:0) > Acetic acid + Hexanoyl-CoA O-Acetylserine + Hydrogen sulfide <> Acetic acid + L-Cysteine + Hydrogen ion Acetic acid + Adenosine triphosphate <> Acetylphosphate + ADP Water + UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine <> Acetic acid + UDP-3-O-(3-Hydroxytetradecanoyl)-D-glucosamine N-Acetyl-D-Glucosamine 6-Phosphate + Water <> Acetic acid + Glucosamine 6-phosphate Water + Pyruvic acid + Ubiquinone-8 > Acetic acid + Carbon dioxide + Ubiquinol-8 Acetaldehyde + Water + NAD > Acetic acid +2 Hydrogen ion + NADH Acetaldehyde + Water + NADP > Acetic acid +2 Hydrogen ion + NADPH N-Acetylornithine + Water <> Acetic acid + Ornithine + L-Ornithine N-Acetyl-L-glutamate 5-semialdehyde + Water > Acetic acid + L-Glutamic-gamma-semialdehyde Acetic acid + Adenosine triphosphate + Coenzyme A <> Acetyl-CoA + Adenosine monophosphate + Pyrophosphate Adenosine triphosphate + Acetic acid <> Pyrophosphate + Acetyl adenylate Acetylphosphate + Water <> Acetic acid + Phosphate Phosphonoacetate + Water <> Acetic acid + Phosphate N-Acetylornithine + Water <> Acetic acid + Ornithine O-Acetylserine + Hydrogen sulfide <> L-Cysteine + Acetic acid Butanoyl-CoA + Acetic acid <> Butyric acid + Acetyl-CoA Acetoacetyl-CoA + Acetic acid <> Acetoacetic acid + Acetyl-CoA O-Acetylserine + Thiosulfate <> Cysteine-S-sulfate + Acetic acid Pyruvic acid + Ubiquinone-1 + Water <> Acetic acid + Ubiquinol-8 + Carbon dioxide o-acetyl-l-homoserine + L-Cysteine <> L-Cystathionine + Acetic acid O-Acetylserine + Hydrogen selenide <> Selenocysteine + Acetic acid O-Acetylserine + Thiosulfate + Thioredoxin + Hydrogen ion <> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetic acid More...o-acetyl-l-homoserine + Selenocysteine <> Selenocystathionine + Acetic acid 3-Hydroxy-5-oxohexanoate + Acetyl-CoA <> 3-Hydroxy-5-oxohexanoyl-CoA + Acetic acid N-Acetyl-L-citrulline + Water <> Acetic acid + Citrulline poly-β-1,6-N-acetyl-D-glucosamine + Water Hydrogen ion + partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine + Acetic acid a 2,3,4-saturated fatty acyl CoA + Acetic acid <> a fatty acid + Acetyl-CoA Coenzyme A + Acetic acid + Adenosine triphosphate > Acetyl-CoA + Pyrophosphate + Adenosine monophosphate Acetoacetic acid + Acetyl-CoA <> Acetoacetyl-CoA + Acetic acid Water + an acetic ester > an alcohol + Acetic acid + Hydrogen ion N-Acetylornithine + Water > Ornithine + Acetic acid Citric acid > Acetic acid + Oxalacetic acid Water + N-Acetyl-D-Glucosamine 6-Phosphate > Glucosamine 6-phosphate + Acetic acid Pyruvic acid + Water + a ubiquinone > Carbon dioxide + a ubiquinol + Acetic acid Acetaldehyde + NADP + Water > Acetic acid + NADPH + Hydrogen ion Acetic acid + Carbon dioxide + Hydrogen ion <> Pyruvic acid + Water UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine + Water > UDP-3-O-(3-Hydroxytetradecanoyl)-D-glucosamine + Acetic acid Adenosine triphosphate + Acetic acid > ADP + Acetylphosphate Adenosine triphosphate + Acetic acid + CoA > Adenosine monophosphate + Pyrophosphate + Acetyl-CoA N-Acetyl-D-galactosamine 6-phosphate + Water > D-Galactosamine 6-phosphate + Acetic acid Acyl-CoA + Acetic acid > a fatty acid anion + Acetyl-CoA Acetyl-CoA + Citric acid > Acetic acid + (3S)-Citryl-CoA Adenosine triphosphate + Acetic acid + [citrate (pro-3S)-lyase](thiol form) > Adenosine monophosphate + Pyrophosphate + [citrate (pro-3S)-lyase](acetyl form) O-Acetylserine + Hydrogen sulfide > L-Cysteine + Acetic acid UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine + Water > UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + Acetic acid N-Acetyl-D-Glucosamine 6-Phosphate + Water > D-glucosamine 6-phosphate + Acetic acid Pyruvic acid + Ubiquinone-10 + Water > Acetic acid + Carbon dioxide + Ubiquinol-1 Acyl-CoA + Acetic acid <> Fatty acid anion + Acetyl-CoA Acetyl-CoA + Citric acid <> Acetic acid + (3S)-Citryl-CoA Adenosine triphosphate + Acetic acid + Citrate (pro-3S)-lyase (thiol form) <> Adenosine monophosphate + Pyrophosphate + Citrate (pro-3S)-lyase (acetyl form) Acetyl-CoA + Oxalic acid <> Acetic acid + Oxalyl-CoA Acetyl-CoA + 3-Hydroxy-5-oxohexanoate > Acetic acid + 3-Hydroxy-5-oxohexanoyl-CoA + 3-Hydroxy-5-oxohexanoyl-CoA N-Acetylornithine + Water > Acetic acid + L-Ornithine monochlorohydrate/ornithine N-Acetylornithine + Water > Ornithine + Acetic acid + Ornithine O-Acetylserine > Hydrogen ion + Acetic acid + L-Cysteine O-Acetylserine + Hydrogen sulfide > Hydrogen ion + Acetic acid + L-Cysteine UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + Water > Acetic acid + UDP-3-O-(3-Hydroxytetradecanoyl)-D-glucosamine N-Acetyl-D-Glucosamine 6-Phosphate + Water + N-Acetyl-D-Glucosamine 6-Phosphate > Acetic acid + Glucosamine 6-phosphate O-Acetylserine + Thiosulfate + Thiosulfate > Cysteine-S-sulfate + Acetic acid Diacetylchitobiose-6-phosphate + Water > N'-monoacetylchitobiose-6'-phosphate + Acetic acid [a holo citrate lyase acyl-carrier protein] + Adenosine triphosphate + Acetic acid > Adenosine monophosphate + Pyrophosphate + an acetyl-[holo citrate lyase acyl-carrier protein] Acetylphosphate + ADP > Adenosine triphosphate + Acetic acid Acetic acid + Adenosine triphosphate + Coenzyme A > Pyrophosphate + Adenosine monophosphate + Acetyl-CoA 2 Pyruvic acid + 2 Water > Carbon dioxide + Acetic acid + Hydrogen ion + Electron Phosphonoacetate + Water <> Acetic acid + Phosphate Acetic acid + Adenosine triphosphate <> Acetylphosphate + ADP Acetic acid + Adenosine triphosphate + Coenzyme A <> Acetyl-CoA + Adenosine monophosphate + Pyrophosphate O-Acetylserine + Hydrogen sulfide <> Acetic acid + L-Cysteine + Hydrogen ion O-Acetylserine + Hydrogen sulfide <> L-Cysteine + Acetic acid Water + UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine <> Acetic acid + UDP-3-O-(3-Hydroxytetradecanoyl)-D-glucosamine N-Acetylornithine + Water <> Acetic acid + Ornithine + L-Ornithine Pyruvic acid + Ubiquinone-1 + Water <> Acetic acid + Ubiquinol-8 + Carbon dioxide Acetic acid + Adenosine triphosphate <> Acetylphosphate + ADP Acetic acid + Adenosine triphosphate + Coenzyme A <> Acetyl-CoA + Adenosine monophosphate + Pyrophosphate Water + UDP-3-O-(3-Hydroxymyristoyl)-N-acetylglucosamine <> Acetic acid + UDP-3-O-(3-Hydroxytetradecanoyl)-D-glucosamine N-Acetylornithine + Water <> Acetic acid + Ornithine + L-Ornithine Pyruvic acid + Ubiquinone-1 + Water <> Acetic acid + Ubiquinol-8 + Carbon dioxide | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SMPDB Pathways: |
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KEGG Pathways: |
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EcoCyc Pathways: |
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Concentrations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Find out more about how we convert literature concentrations. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Spectra | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Spectra: | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
References | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
References: |
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Synthesis Reference: | Law, David John. Process for the preparation of carboxylic acids and/or derivatives thereof. PCT Int. Appl. (2007), 14pp. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Material Safety Data Sheet (MSDS) | Download (PDF) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Links | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
External Links: |
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Enzymes
- General function:
- Involved in pyridoxal phosphate binding
- Specific function:
- O(4)-succinyl-L-homoserine + L-cysteine = L- cystathionine + succinate
- Gene Name:
- metB
- Uniprot ID:
- P00935
- Molecular weight:
- 41550
Reactions
O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate. |
- General function:
- Involved in magnesium ion binding
- Specific function:
- Pyruvate + ferricytochrome b1 + H(2)O = acetate + CO(2) + ferrocytochrome b1
- Gene Name:
- poxB
- Uniprot ID:
- P07003
- Molecular weight:
- 62011
Reactions
Pyruvate + ubiquinone + H(2)O = acetate + CO(2) + ubiquinol. |
- General function:
- Involved in kinase activity
- Specific function:
- Involved in the activation of acetate to acetyl CoA and the secretion of acetate. During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically
- Gene Name:
- ackA
- Uniprot ID:
- P0A6A3
- Molecular weight:
- 43290
Reactions
ATP + acetate = ADP + acetyl phosphate. |
ATP + propanoate = ADP + propanoyl phosphate. |
- General function:
- Involved in UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
- Specific function:
- The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal
- Gene Name:
- lpxC
- Uniprot ID:
- P0A725
- Molecular weight:
- 33956
Reactions
UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H(2)O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. |
- General function:
- Involved in carbon-carbon lyase activity
- Specific function:
- Represents a citryl-ACP lyase
- Gene Name:
- citE
- Uniprot ID:
- P0A9I1
- Molecular weight:
- 33109
Reactions
Citrate = acetate + oxaloacetate. |
(3S)-citryl-CoA = acetyl-CoA + oxaloacetate. |
- General function:
- Involved in acylphosphatase activity
- Specific function:
- An acylphosphate + H(2)O = a carboxylate + phosphate
- Gene Name:
- yccX
- Uniprot ID:
- P0AB65
- Molecular weight:
- 10300
Reactions
An acylphosphate + H(2)O = a carboxylate + phosphate. |
- General function:
- Involved in cysteine biosynthetic process from serine
- Specific function:
- O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate
- Gene Name:
- cysK
- Uniprot ID:
- P0ABK5
- Molecular weight:
- 34489
Reactions
O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate. |
3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride. |
- General function:
- Involved in hydrolase activity
- Specific function:
- N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate
- Gene Name:
- nagA
- Uniprot ID:
- P0AF18
- Molecular weight:
- 40949
Reactions
N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate. |
- General function:
- Involved in kinase activity
- Specific function:
- ATP + propanoate = ADP + propanoyl phosphate
- Gene Name:
- tdcD
- Uniprot ID:
- P11868
- Molecular weight:
- 43384
Reactions
ATP + propanoate = ADP + propanoyl phosphate. |
ATP + acetate = ADP + acetyl phosphate. |
- General function:
- Involved in cysteine biosynthetic process from serine
- Specific function:
- Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product
- Gene Name:
- cysM
- Uniprot ID:
- P16703
- Molecular weight:
- 32664
Reactions
O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate. |
- General function:
- Involved in oxidoreductase activity
- Specific function:
- Involved in the breakdown of putrescine. Was previously shown to have a weak but measurable ALDH enzyme activity that prefers NADP over NAD as coenzyme
- Gene Name:
- puuC
- Uniprot ID:
- P23883
- Molecular weight:
- 53418
Reactions
Gamma-glutamyl-gamma-aminobutyraldehyde + NAD(+) + H(2)O = gamma-glutamyl-gamma-aminobutyrate + NADH. |
An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H. |
- General function:
- Involved in zinc ion binding
- Specific function:
- Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde
- Gene Name:
- argE
- Uniprot ID:
- P23908
- Molecular weight:
- 42347
Reactions
N(2)-acetyl-L-ornithine + H(2)O = acetate + L-ornithine. |
- General function:
- Involved in acetate-CoA ligase activity
- Specific function:
- Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis
- Gene Name:
- acs
- Uniprot ID:
- P27550
- Molecular weight:
- 72093
Reactions
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. |
- General function:
- Involved in ATP binding
- Specific function:
- Catalyzes two reactions:the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP
- Gene Name:
- purT
- Uniprot ID:
- P33221
- Molecular weight:
- 42433
Reactions
Formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate. |
- General function:
- Involved in oxidoreductase activity
- Specific function:
- Catalyzes the NADP-dependent oxidation of diverse aldehydes such as chloroacetaldehyde, acetaldehyde, propionaldehyde, benzaldehyde, mafosfamide, 4- hydroperoxycyclophosphamide. Its preferred substrates are acetaldehyde and chloroacetaldehyde
- Gene Name:
- aldB
- Uniprot ID:
- P37685
- Molecular weight:
- 56306
- General function:
- Involved in hydrolase activity
- Specific function:
- N-acetyl-D-galactosamine 6-phosphate + H(2)O = D-galactosamine 6-phosphate + acetate
- Gene Name:
- agaA
- Uniprot ID:
- P42906
- Molecular weight:
- 17519
Reactions
N-acetyl-D-galactosamine 6-phosphate + H(2)O = D-galactosamine 6-phosphate + acetate. |
- General function:
- Energy production and conversion
- Specific function:
- Covalent carrier of the coenzyme of citrate lyase
- Gene Name:
- citD
- Uniprot ID:
- P69330
- Molecular weight:
- 10689
- General function:
- Involved in citrate CoA-transferase activity
- Specific function:
- Represents a citrate:acetyl-ACP transferase
- Gene Name:
- citF
- Uniprot ID:
- P75726
- Molecular weight:
- 55172
Reactions
Citrate = acetate + oxaloacetate. |
Acetyl-CoA + citrate = acetate + (3S)-citryl-CoA. |
- General function:
- Involved in CoA-transferase activity
- Specific function:
- Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA
- Gene Name:
- atoD
- Uniprot ID:
- P76458
- Molecular weight:
- 23526
Reactions
Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA. |
- General function:
- Involved in CoA-transferase activity
- Specific function:
- Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA
- Gene Name:
- atoA
- Uniprot ID:
- P76459
- Molecular weight:
- 22960
Reactions
Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA. |
- General function:
- Involved in [citrate (pro-3S)-lyase] ligase activity
- Specific function:
- Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
- Gene Name:
- citC
- Uniprot ID:
- P77390
- Molecular weight:
- 40077
Reactions
ATP + acetate + [citrate (pro-3S)-lyase](thiol form) = AMP + diphosphate + [citrate (pro-3S)-lyase](acetyl form). |
- General function:
- Involved in prosthetic group biosynthetic process
- Specific function:
- Transfers 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein
- Gene Name:
- citX
- Uniprot ID:
- P0A6G5
- Molecular weight:
- 20270
Reactions
2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate. |
- General function:
- Not Available
- Specific function:
- Not Available
- Gene Name:
- yjdM
- Uniprot ID:
- P0AFJ1
- Molecular weight:
- Not Available
- General function:
- polysaccharide catabolic process
- Specific function:
- ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF. It can also use chitobiose and chitotriose as substrates.
- Gene Name:
- chbG
- Uniprot ID:
- P37794
- Molecular weight:
- 27773
Reactions
2-(acetylamino)-4-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + H(2)O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate |
Transporters
- General function:
- Lipid transport and metabolism
- Specific function:
- Responsible for the intake of short-chain fatty acids
- Gene Name:
- atoE
- Uniprot ID:
- P76460
- Molecular weight:
- 47527
- General function:
- Involved in transporter activity
- Specific function:
- Transports acetate
- Gene Name:
- actP
- Uniprot ID:
- B1XCV3
- Molecular weight:
- 59197
- General function:
- Involved in transporter activity
- Specific function:
- Transports acetate
- Gene Name:
- actP
- Uniprot ID:
- C5A160
- Molecular weight:
- 59197
- General function:
- Involved in transporter activity
- Specific function:
- Transports acetate. Also able to transport glycolate
- Gene Name:
- actP
- Uniprot ID:
- P32705
- Molecular weight:
- 59197
- General function:
- Involved in transporter activity
- Specific function:
- Non-specific porin
- Gene Name:
- ompN
- Uniprot ID:
- P77747
- Molecular weight:
- 41220
- General function:
- Involved in transporter activity
- Specific function:
- Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
- Gene Name:
- phoE
- Uniprot ID:
- P02932
- Molecular weight:
- 38922
- General function:
- Involved in transporter activity
- Specific function:
- OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
- Gene Name:
- ompF
- Uniprot ID:
- P02931
- Molecular weight:
- 39333
- General function:
- Involved in transporter activity
- Specific function:
- Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
- Gene Name:
- ompC
- Uniprot ID:
- P06996
- Molecular weight:
- 40368