Acetic acid (ECMDB00042) (M2MDB000012)

General function:

Involved in pyridoxal phosphate binding

Specific function:

O(4)-succinyl-L-homoserine + L-cysteine = L- cystathionine + succinate

Gene Name:

metB

Uniprot ID:

P00935

Molecular weight:

41550

Reactions

General function:

Involved in magnesium ion binding

Specific function:

Pyruvate + ferricytochrome b1 + H(2)O = acetate + CO(2) + ferrocytochrome b1

Gene Name:

poxB

Uniprot ID:

P07003

Molecular weight:

62011

Reactions

General function:

Involved in kinase activity

Specific function:

Involved in the activation of acetate to acetyl CoA and the secretion of acetate. During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically

Gene Name:

ackA

Uniprot ID:

P0A6A3

Molecular weight:

43290

Reactions

General function:

Involved in UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity

Specific function:

The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal

Gene Name:

lpxC

Uniprot ID:

P0A725

Molecular weight:

33956

Reactions

General function:

Involved in carbon-carbon lyase activity

Specific function:

Represents a citryl-ACP lyase

Gene Name:

citE

Uniprot ID:

P0A9I1

Molecular weight:

33109

Reactions

General function:

Involved in acylphosphatase activity

Specific function:

An acylphosphate + H(2)O = a carboxylate + phosphate

Gene Name:

yccX

Uniprot ID:

P0AB65

Molecular weight:

10300

Reactions

General function:

Involved in cysteine biosynthetic process from serine

Specific function:

O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate

Gene Name:

cysK

Uniprot ID:

P0ABK5

Molecular weight:

34489

Reactions

General function:

Involved in hydrolase activity

Specific function:

N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate

Gene Name:

nagA

Uniprot ID:

P0AF18

Molecular weight:

40949

Reactions

General function:

Involved in kinase activity

Specific function:

ATP + propanoate = ADP + propanoyl phosphate

Gene Name:

tdcD

Uniprot ID:

P11868

Molecular weight:

43384

Reactions

General function:

Involved in cysteine biosynthetic process from serine

Specific function:

Two cysteine synthase enzymes are found. Both catalyze the same reaction. Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product

Gene Name:

cysM

Uniprot ID:

P16703

Molecular weight:

32664

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Involved in the breakdown of putrescine. Was previously shown to have a weak but measurable ALDH enzyme activity that prefers NADP over NAD as coenzyme

Gene Name:

puuC

Uniprot ID:

P23883

Molecular weight:

53418

Reactions

General function:

Involved in zinc ion binding

Specific function:

Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde

Gene Name:

argE

Uniprot ID:

P23908

Molecular weight:

42347

Reactions

General function:

Involved in acetate-CoA ligase activity

Specific function:

Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis

Gene Name:

acs

Uniprot ID:

P27550

Molecular weight:

72093

Reactions

General function:

Involved in ATP binding

Specific function:

Catalyzes two reactions:the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP

Gene Name:

purT

Uniprot ID:

P33221

Molecular weight:

42433

Reactions

General function:

Involved in oxidoreductase activity

Specific function:

Catalyzes the NADP-dependent oxidation of diverse aldehydes such as chloroacetaldehyde, acetaldehyde, propionaldehyde, benzaldehyde, mafosfamide, 4- hydroperoxycyclophosphamide. Its preferred substrates are acetaldehyde and chloroacetaldehyde

Gene Name:

aldB

Uniprot ID:

P37685

Molecular weight:

56306

General function:

Involved in hydrolase activity

Specific function:

N-acetyl-D-galactosamine 6-phosphate + H(2)O = D-galactosamine 6-phosphate + acetate

Gene Name:

agaA

Uniprot ID:

P42906

Molecular weight:

17519

Reactions

General function:

Energy production and conversion

Specific function:

Covalent carrier of the coenzyme of citrate lyase

Gene Name:

citD

Uniprot ID:

P69330

Molecular weight:

10689

General function:

Involved in citrate CoA-transferase activity

Specific function:

Represents a citrate:acetyl-ACP transferase

Gene Name:

citF

Uniprot ID:

P75726

Molecular weight:

55172

Reactions

General function:

Involved in CoA-transferase activity

Specific function:

Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA

Gene Name:

atoD

Uniprot ID:

P76458

Molecular weight:

23526

Reactions

General function:

Involved in CoA-transferase activity

Specific function:

Acyl-CoA + acetate = a fatty acid anion + acetyl-CoA

Gene Name:

atoA

Uniprot ID:

P76459

Molecular weight:

22960

Reactions

General function:

Involved in [citrate (pro-3S)-lyase] ligase activity

Specific function:

Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase

Gene Name:

citC

Uniprot ID:

P77390

Molecular weight:

40077

Reactions

General function:

Involved in prosthetic group biosynthetic process

Specific function:

Transfers 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein

Gene Name:

citX

Uniprot ID:

P0A6G5

Molecular weight:

20270

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

yjdM

Uniprot ID:

P0AFJ1

Molecular weight:

Not Available

General function:

polysaccharide catabolic process

Specific function:

ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF. It can also use chitobiose and chitotriose as substrates.

Gene Name:

chbG

Uniprot ID:

P37794

Molecular weight:

27773

Reactions