Reaction Details
Reaction:
1.0Thumb+3.0Thumb1.0Thumb+1.0Thumb+2.0Thumb+1.0Thumb+1.0Thumb
1.0Guanosine triphosphate + 3.0Water ↔ 1.02,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + 1.0Formic acid + 2.0Hydrogen ion + 1.0Pyrophosphate + 1.02,5-diamino-6-hydroxy-4-(5-phospho-D-ribosylamino)pyrimidine
Enzymes:
External Links:
ResourceLink
Kegg Reaction ID:R00425
EcoCyc Reaction ID:GTP-CYCLOHYDRO-II-RXN
References:
  • Uniprot Consortium (2012). "Reorganizing the protein space at the Universal Protein Resource (UniProt)." Nucleic Acids Res 40:D71-D75. Pubmed: 22102590
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831