Identification
Name:Probable hypoxanthine oxidase XdhD
Synonyms:Not Available
Gene Name:xdhD
Enzyme Class:Not Available
Biological Properties
General Function:xanthine catabolic process
Specific Function:Probably has no xanthine dehydrogenase activity; however deletion results in increased adenine sensitivity, suggesting that this protein contributes to the conversion of adenine to guanine nucleotides during purine salvage.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
2 iron, 2 sulfur cluster binding
cytosol
flavin adenine dinucleotide binding
iron ion binding
molybdopterin cofactor binding
oxidoreductase activity, acting on the aldehyde or oxo group of donors
purine ribonucleoside salvage
xanthine catabolic process
xanthine dehydrogenase activity
xanthine oxidase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>2871
atgatcatccactttactttaaatggcgcgcctcaggagctaaccgttaatccaggcgaa
aacgtgcaaaagctgttgtttaacatgggaatgcactctgtacgcaacagtgatgatggt
ttcgggtttgccggttctgacgcaataatctttaacggtaatatcgttaacgcgtccttg
cttattgccgcacagttagagaaggcagatattcgtaccgcagaatctctgggcaaatgg
aacgagttaagtctggttcaacaggcaatggttgatgttggcgtggtgcagtctggttat
aacgatccagctgcagctctgattatcaccgatcttctcgatcgcatcgccgcacctacc
cgcgaagagatcgacgacgcgctttctggtttgttcagccgcgatgctggctggcagcaa
tactatcaggtcattgaactggcggttgcacgtaaaaataatccgcaggccaccattgat
atcgctccgactttccgtgacgacctagaagtcattggtaagcattatcctaaaactgat
gccgcgaaaatggtgcaggcgaaaccctgctatgttgaagaccgcgtaacggctgacgcc
tgcgtcattaaaatgttacgtagcccacacgctcacgcactgattactcatctggatgtc
agcaaagctgaagccttaccgggcgtcgttcacgttattactcacctgaattgcccggat
atctactataccccgggtggtcagagcgcaccggaaccgtcaccgcttgaccgccgtatg
ttcggcaagaaaatgcgtcacgtcggcgatcgtgttgctgcggtcgtcgcagaaagtgaa
gaaattgcgctcgaagcactgaagctcatcgacgttgaatatgaagtgcttaagccggta
atgtcgatcgacgaagcaatggcggaagatgcgcctgtcgtgcacgatgaaccggtggtg
tatgttgctggtgcgccagatactctggaagacgataacagccatgcagcccagcgcggc
gagcatatgatcatcaacttcccgatcggttctcgccctcgcaaaaatatcgccgccagt
attcatggtcatattggcgatatggacaaaggctttgccgatgccgatgtgatcattgag
cgaacctataactcaacgcaagcgcagcagtgcccgactgaaacacatatctgctttact
cgtatggacggcgatcgtctggttatccacgcctccacccaggtaccatggcacttacgc
cgccaggtcgcgcgcctcgtgggcatgaaacagcataaagttcatgtcattaaagagcga
gttggcggcggttttggttccaaacaggacatcctgctggaagaagtgtgcgcctgggca
acctgcgtgaccgggcgtccggtactgttccgctacacccgtgaagaagagtttattgct
aacacctctcgtcacgtcgcgaaagtcaccgtcaaactgggagcgaaaaaagatggtcgc
ctgacggcagtgaagatggatttccgcgccaacactggcccttacggcaaccactcactc
accgtaccgtgtaacggaccggcgctgtcgctgccgttatatccgtgcgataacgtcgat
ttccaggtcaccacctactacagcaacatttgcccaaatggtgcttatcagggttatggc
gcaccgaaaggtaacttcgctatcaccatggcattagcggaactggctgaacagttacag
atcgaccaactggaaattatcgaacgtaaccgggtacacgaagggcaagagctgaaaatt
ctcggtgcaatcggtgaaggtaaagcgccgacctccgttccttccgccgccagctgtgca
ctggaagagatcctgcgtcagggtcgcgagatgatccaatggtcgtcaccgaaaccgcaa
aatggtgactggcacatcggtcgcggcgtcgccattatcatgcagaaatcgggtatcccg
gatatcgatcaggctaactgcatgatcaaactggaatcggacggcacctttatcgttcat
tctggcggtgcggatattggtactggtctggatactgtagtgacgaaactggcagcagaa
gtgctgcactgcccaccgcaggacgtgcatgttatctccggtgataccgatcatgcgttg
tttgataaaggcgcatatgcctcgtccggtacttgcttctcgggtaacgcggcgcgtttg
gcagcggaaaatctacgggagaaaattctgttccacggcgcgcaaatgttgggtgagcca
gtggcagatgttcaactggcaacgccgggcgtcgtgcgcggcaagaaaggcgaagttagt
ttcggggatattgcccataaaggcgaaaccggcaccggctttggttcactggtgggaact
ggcagttatatcacgcctgatttcgccttcccgtatggcgcaaacttcgctgaagttgcc
gtcaacacgcgtacgggtgaaatccgcctggataaattctacgccttgctggactgcggt
acaccggtcaatccagagttagcgttgggacaaatctacggtgccaccctgcgtgctatc
ggccacagtatgagcgaagagatcatttatgacgccgaaggtcacccgttaacgcgtgat
ttacgcagttacggcgcaccgaaaattggtgacattccgcgtgatttccgcgctgtgctg
gtgccgagcgacgataaagtcggcccgttcggggcgaaatcgatctcggaaatcggtgta
aatggcgcagctccggcgattgctaccgcaattcacgatgcatgcggcatctggttacgc
gaatggcatttcacaccggagaaaatactcactgcgctggaaaaaatataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:956
Protein Molecular Weight:103517
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Probable hypoxanthine oxidase XdhD
MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFAGSDAIIFNGNIVNASL
LIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPT
REEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATIDIAPTFRDDLEVIGKHYPKTD
AAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHLDVSKAEALPGVVHVITHLNCPD
IYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVVAESEEIALEALKLIDVEYEVLKPV
MSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNSHAAQRGEHMIINFPIGSRPRKNIAAS
IHGHIGDMDKGFADADVIIERTYNSTQAQQCPTETHICFTRMDGDRLVIHASTQVPWHLR
RQVARLVGMKQHKVHVIKERVGGGFGSKQDILLEEVCAWATCVTGRPVLFRYTREEEFIA
NTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVD
FQVTTYYSNICPNGAYQGYGAPKGNFAITMALAELAEQLQIDQLEIIERNRVHEGQELKI
LGAIGEGKAPTSVPSAASCALEEILRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIP
DIDQANCMIKLESDGTFIVHSGGADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHAL
FDKGAYASSGTCFSGNAARLAAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVS
FGDIAHKGETGTGFGSLVGTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCG
TPVNPELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVL
VPSDDKVGPFGAKSISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI
References
External Links:
ResourceLink
Uniprot ID:Q46814
Uniprot Name:XDHD_ECOLI
CCDB:XDHD_ECOLI
General Reference:Not Available